| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abscess | D000038 | 13 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hemoglobinopathies | D006453 | 7 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hemorrhagic Fever with Renal Syndrome | D006480 | 3 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fernandez-Gomez FJ et al. | Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway. | 2005 | Br. J. Pharmacol. | pmid:15655518 |
| Paucard A et al. | Time course of oxidative stress, lesion and edema after intrastriatal injection of malonate in rat: effect of alpha-phenyl-N-tert-butylnitrone. | 2005 | Fundam Clin Pharmacol | pmid:15660960 |
| Innocenti A et al. | Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15664815 |
| Thatcher GR et al. | Novel nitrates as NO mimetics directed at Alzheimer's disease. | 2004 | J. Alzheimers Dis. | pmid:15665418 |
| Lee GY et al. | Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester. | 2005 | Thromb. Res. | pmid:15668191 |
| pmid:15673245 | ||||
| Bufetov EN et al. | [Effect of malonate on the structural and functional changes of wheat Triticum aestivum L. root cells]. | 2004 | Tsitologiia | pmid:15704878 |
| Larson SB et al. | Crystallographic structure of the T=1 particle of brome mosaic virus. | 2005 | J. Mol. Biol. | pmid:15713465 |
| Hurth MA et al. | Impaired pH homeostasis in Arabidopsis lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast. | 2005 | Plant Physiol. | pmid:15728336 |
| pmid:15730253 | ||||
| Bozdech Z and Ginsburg H | Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes. | 2005 | Malar. J. | pmid:15774020 |
| pmid:15780274 | ||||
| Kaya K et al. | Selective control of toxic Microcystis water blooms using lysine and malonic acid: an enclosure experiment. | 2005 | Environ. Toxicol. | pmid:15793822 |
| Kapich AN et al. | Involvement of lipid peroxidation in the degradation of a non-phenolic lignin model compound by manganese peroxidase of the litter-decomposing fungus Stropharia coronilla. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15796893 |
| Scheer JM et al. | Malonate-assisted purification of human caspases. | 2005 | Protein Expr. Purif. | pmid:15802232 |
| pmid:15804432 | ||||
| Mokhova EN and Khailova LS | Involvement of mitochondrial inner membrane anion carriers in the uncoupling effect of fatty acids. | 2005 | Biochemistry Mosc. | pmid:15807654 |
| Ishikura S et al. | Structural and functional characterization of rabbit and human L-gulonate 3-dehydrogenase. | 2005 | J. Biochem. | pmid:15809331 |
| pmid:15836236 | ||||
| Diao ZY et al. | [Establishment of the organotypic model of amyotrophic lateral sclerosis from the SD rats' spinal cord]. | 2005 | Beijing Da Xue Xue Bao | pmid:15841139 |
| pmid:15845418 | ||||
| pmid:15845422 | ||||
| Mitreva M et al. | Investigating hookworm genomes by comparative analysis of two Ancylostoma species. | 2005 | BMC Genomics | pmid:15854223 |
| pmid:15862280 | ||||
| pmid:15864796 | ||||
| Sebban M et al. | Tautomerism and 1H, 13C and 15N NMR spectral assignments of some nitro derivatives of malonic acid diamide. | 2005 | Magn Reson Chem | pmid:15864818 |
| Maloney PC et al. | Measurement of the substrate dissociation constant of a solubilized membrane carrier. Substrate stabilization of OxlT, the anion exchange protein of Oxalobacter formigenes. | 1992 | J. Biol. Chem. | pmid:1587833 |
| Azurmendi HF et al. | Half-of-the-sites binding of reactive intermediates and their analogues to 4-oxalocrotonate tautomerase and induced structural asymmetry of the enzyme. | 2005 | Biochemistry | pmid:15909987 |
| pmid:15917184 | ||||
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| pmid:15941271 | ||||
| pmid:15941297 | ||||
| Nguyen TH et al. | Conformations, energies, and intramolecular hydrogen bonds in dicarboxylic acids: implications for the design of synthetic dicarboxylic acid receptors. | 2005 | J Comput Chem | pmid:15962275 |
| Fernandez-Gomez FJ et al. | Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. | 2005 | Neuroscience | pmid:15964487 |
| pmid:15969532 | ||||
| Kachlicki P et al. | Profiling isoflavone conjugates in root extracts of lupine species with LC/ESI/MSn systems. | 2005 | J Mass Spectrom | pmid:15971291 |
| Lorenzo M et al. | Inhibition of laccase activity from Trametes versicolor by heavy metals and organic compounds. | 2005 | Chemosphere | pmid:15993161 |
| Lorenc-Koci E et al. | 1,2,3,4-Tetrahydroisoquinoline protects terminals of dopaminergic neurons in the striatum against the malonate-induced neurotoxicity. | 2005 | Brain Res. | pmid:16004976 |
| de Lago E et al. | UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | 2006 | Eur Neuropsychopharmacol | pmid:16006105 |
| Wycherley G et al. | Oxidative phosphorylation and the tricarboxylic acid cycle are essential for normal development of mouse ovarian follicles. | 2005 | Hum. Reprod. | pmid:16006477 |
| Sone N et al. | Adenosine triphosphate synthesis by electrochemical proton gradient in vesicles reconstituted from purified adenosine triphosphatase and phospholipids of thermophilic bacterium. | 1977 | J. Biol. Chem. | pmid:16011 |
| pmid:16018587 | ||||
| pmid:16018886 | ||||
| Mizuarai S et al. | Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. | 2005 | J. Biol. Chem. | pmid:16027120 |
| pmid:16028959 | ||||
| Baby SM et al. | Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells. | 2005 | Histochem. Cell Biol. | pmid:16034640 |
| pmid:16035004 | ||||
| pmid:16041743 | ||||
| pmid:16046907 | ||||
| pmid:16081081 |