| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Teratoma | D013724 | 4 associated lipids |
| Hemoglobinopathies | D006453 | 7 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hoenke S et al. | Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. | 2000 | Biochemistry | pmid:11052675 |
| Koo JH et al. | The malonate decarboxylase operon of Acinetobacter calcoaceticus KCCM 40902 is regulated by malonate and the transcriptional repressor MdcY. | 2000 | J. Bacteriol. | pmid:11053382 |
| Tóth V and Emódy L | Proteus virulence: involvement of the pore forming alpha-hemolysin (a short review). | 2000 | Acta Microbiol Immunol Hung | pmid:11056765 |
| Ward OP and Singh A | Enzymatic asymmetric synthesis by decarboxylases. | 2000 | Curr. Opin. Biotechnol. | pmid:11102784 |
| Lee HY et al. | Identification and characterization of a novel transcriptional regulator, MatR, for malonate metabolism in Rhizobium leguminosarum bv. trifolii. | 2000 | Eur. J. Biochem. | pmid:11106435 |
| Ling F et al. | A role for MHR1, a gene required for mitochondrial genetic recombination, in the repair of damage spontaneously introduced in yeast mtDNA. | 2000 | Nucleic Acids Res. | pmid:11121487 |
| Ramaseshan M et al. | Solid phase combinatorial synthesis of a library of macro-heterocycles and related acyclic compounds. | 2000 Nov-Dec | J Comb Chem | pmid:11126291 |
| Kamo T et al. | Changes in the content and biosynthesis of phytoalexins in banana fruit. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11129580 |
| pmid:11141054 | ||||
| Dobosz M et al. | Synthesis of new derivatives of 3-benzyl-4-R-delta 2-1,2,4-triazolin-5-one and 3,3'-methylidyne bis(4-R-1,2,4-delta 2-triazolin-5-one). | 2000 May-Jun | Acta Pol Pharm | pmid:11143710 |
| Andreassen OA et al. | Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. | 2001 | Exp. Neurol. | pmid:11161607 |
| Van Westerlaak MG et al. | Chronic mitochondrial inhibition induces glutamate-mediated corticomotoneuron death in an organotypic culture model. | 2001 | Exp. Neurol. | pmid:11161628 |
| Piasecka M et al. | Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. | 2001 | Andrologia | pmid:11167513 |
| Mossakowski MJ et al. | Effect of sodium glutamate on the morphology and histochemistry of experimental gliopathy induced in vitro by ammonia and sodium malonate. | 1975 Jan-Mar | Neuropatol Pol | pmid:1118055 |
| Ruiz-Pérez C et al. | Magnetic coupling through the carbon skeleton of malonate in two polymorphs of ([Cu(bpy)(H2O)][Cu(bpy)(mal)(H2O)])(ClO4)2 (H2mal = malonic acid; bpy = 2,2'-bipyridine). | 2000 | Inorg Chem | pmid:11196779 |
| Meldrum A et al. | Role of corticostriatal and nigrostriatal inputs in malonate-induced striatal toxicity. | 2001 | Neuroreport | pmid:11201098 |
| pmid:11211254 | ||||
| Matharu A et al. | Contributions of the substrate-binding arginine residues to maleate-induced closure of the active site of Escherichia coli aspartate aminotransferase. | 2001 | Eur. J. Biochem. | pmid:11248682 |
| Lancaster CR et al. | A third crystal form of Wolinella succinogenes quinol:fumarate reductase reveals domain closure at the site of fumarate reduction. | 2001 | Eur. J. Biochem. | pmid:11248702 |
| Kavitha J and Subbaraju GV | Synthesis of N-[3,4-dimethoxyphenyl)propanoyl]pyrrole, a metabolite of Piper brachystachyum. | 2000 | J Asian Nat Prod Res | pmid:11252681 |
| McPherson A | A comparison of salts for the crystallization of macromolecules. | 2001 | Protein Sci. | pmid:11266627 |
| Stokes AH et al. | Attenuation of malonate toxicity in primary mesencephalic cultures using the GABA transport blocker, NO-711. | 2001 | J. Neurosci. Res. | pmid:11276050 |
| pmid:11292077 | ||||
| Demougeot C et al. | N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury. | 2001 | J. Neurochem. | pmid:11299303 |
| Nixdorf WL et al. | Enhancement of 3,4-methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate. | 2001 | J. Neurochem. | pmid:11299327 |
| Cotton FA et al. | The simplest supramolecular complexes containing pairs of Mo(2)(formamidinate)(3) units linked with various dicarboxylates: preparative methods, structures, and electrochemistry. | 2001 | Inorg Chem | pmid:11300824 |
| pmid:11312968 | ||||
| Toki K et al. | Anthocyanins from the scarlet flowers of Anemone coronaria. | 2001 | Phytochemistry | pmid:11314957 |
| pmid:11345467 | ||||
| pmid:11354672 | ||||
| pmid:11358255 | ||||
| Li D et al. | Heterologous expression of athermostable manganese peroxidase from Dichomitus squalens in Phanerochaete chrysosporium. | 2001 | Arch. Biochem. Biophys. | pmid:11368016 |
| Hall IH et al. | Specific inhibition of type II inosine monophosphate dehydrogenase activity of Tmolt4 T cell human leukaemia cells by 3-methoxy and di-benzohydroxamic acids, maleic hydrazide and malonic acids. | 2001 | J. Pharm. Pharmacol. | pmid:11370715 |
| Kremer L et al. | Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II. | 2001 | J. Biol. Chem. | pmid:11373295 |
| pmid:11388410 | ||||
| Pohl NL et al. | Remarkably broad substrate tolerance of malonyl-CoA synthetase, an enzyme capable of intracellular synthesis of polyketide precursors. | 2001 | J. Am. Chem. Soc. | pmid:11403625 |
| Marinier A et al. | Novel mimics of sialyl Lewis X: design, synthesis and biological activity of a series of 2- and 3-malonate substituted galactoconjugates. | 2001 | Bioorg. Med. Chem. | pmid:11408160 |
| Ehrhart J and Zeevalk GD | Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures. | 2001 | J. Neurochem. | pmid:11413233 |
| pmid:11421681 | ||||
| pmid:11421699 | ||||
| Plasterer TN et al. | Survey of human mitochondrial diseases using new genomic/proteomic tools. | 2001 | Genome Biol. | pmid:11423010 |
| Bundy JG et al. | An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress. | 2001 | FEBS Lett. | pmid:11434921 |
| pmid:11442368 | ||||
| Löhr W et al. | The azure dyes: their purification and physicochemical properties. II. Purification of azure B. | 1975 | Stain Technol | pmid:1145656 |
| Trost BM and Lee CB | Geminal dicarboxylates as carbonyl surrogates for asymmetric synthesis. Part I. Asymmetric addition of malonate nucleophiles. | 2001 | J. Am. Chem. Soc. | pmid:11457099 |
| pmid:11457100 | ||||
| pmid:11457183 | ||||
| pmid:11468376 | ||||
| Crompton M et al. | A kinetic study of sulphate transport in rat liver mitochondria. | 1975 | Biochem. J. | pmid:1147910 |
| pmid:11485332 |