Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Lin X et al. Acetate represents a major product of heptanoate and octanoate beta-oxidation in hepatocytes isolated from neonatal piglets. 1996 Biochem. J. pmid:8761477
Albers DS et al. Damage to dopaminergic nerve terminals in mice by combined treatment of intrastriatal malonate with systemic methamphetamine or MPTP. 1996 Brain Res. pmid:8773791
Bazzett TJ et al. Synergistic effects of chronic exposure to subthreshold concentrations of quinolinic acid and malonate in the rat striatum. 1996 Brain Res. pmid:8773793
Connop BP et al. Attenuation of malonate-induced degeneration of the nigrostriatal pathway by inhibitors of nitric oxide synthase. 1996 Neuropharmacology pmid:8793908
Klein BY et al. Opposing effects on mitochondrial membrane potential by malonate and levamisole, whose effect on cell-mediated mineralization is antagonistic. 1996 J. Cell. Biochem. pmid:8825423
Arihara K et al. Contribution of the glycolytic pathway to enzymatic metmyoglobin reduction in myocytes. 1996 Biochem. Mol. Biol. Int. pmid:8850528
Podell M et al. Methylmalonic and malonic aciduria in a dog with progressive encephalomyelopathy. 1996 Metab Brain Dis pmid:8869944
Geddes JW et al. Hippocampal damage and cytoskeletal disruption resulting from impaired energy metabolism. Implications for Alzheimer disease. 1996 May-Aug Mol. Chem. Neuropathol. pmid:8871943
Hu JZ et al. High resolution 1H spectra of powdered solids observed by Hahn echo pulse sequence with magic-angle spinning. 1996 Solid State Nucl Magn Reson pmid:8925269
Borutaite V et al. Kinetic analysis of changes in activity of heart mitochondrial oxidative phosphorylation system induced by ischemia. 1996 J. Mol. Cell. Cardiol. pmid:8930814