Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Karakikes I et al. Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. 2009 PLoS ONE pmid:19649297
Brown AK et al. Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. 2009 PLoS ONE pmid:19609444
Pistollato F et al. Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. 2009 PLoS ONE pmid:19587783
Shi D et al. A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris. 2011 PLoS ONE pmid:22174908
Schiff M et al. Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin mice. 2011 PLoS ONE pmid:22174907
Tiziani S et al. Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. 2009 PLoS ONE pmid:19158949
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Finley LW et al. Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. 2011 PLoS ONE pmid:21858060
Jeong YS et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. 2011 PLoS ONE pmid:21811631
Rogers GW et al. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. 2011 PLoS ONE pmid:21799747
Ruiz M et al. A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. 2012 PLoS ONE pmid:23056435
Egea PF et al. Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. 2008 PLoS ONE pmid:18953414
Hashimoto T et al. Evidence for the mitochondrial lactate oxidation complex in rat neurons: demonstration of an essential component of brain lactate shuttles. 2008 PLoS ONE pmid:18698340
Lin H et al. The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. 2011 PLoS ONE pmid:21552483
García-Torres I et al. Identification of amino acids that account for long-range interactions in two triosephosphate isomerases from pathogenic trypanosomes. 2011 PLoS ONE pmid:21533154
Matar-Merheb R et al. Structuring detergents for extracting and stabilizing functional membrane proteins. 2011 PLoS ONE pmid:21483854
Minato Y et al. Malonate inhibits virulence gene expression in Vibrio cholerae. 2013 PLoS ONE pmid:23675480
Gallo M et al. MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. 2011 PLoS ONE pmid:21448454
Kim J et al. Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. 2008 PLoS ONE pmid:18335064
Boily G et al. SirT1 regulates energy metabolism and response to caloric restriction in mice. 2008 PLoS ONE pmid:18335035
Rakhimova E et al. Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection. 2008 PLoS ONE pmid:18301762
Rudrappa T et al. Cyanogenic pseudomonads influence multitrophic interactions in the rhizosphere. 2008 PLoS ONE pmid:18446201
Qi M et al. Genome sequence analyses of Pseudomonas savastanoi pv. glycinea and subtractive hybridization-based comparative genomics with nine pseudomonads. 2011 PLoS ONE pmid:21304594
Yang L et al. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. 2009 PLoS ONE pmid:19484125
Hauser PM et al. Comparative genomics suggests that the fungal pathogen pneumocystis is an obligate parasite scavenging amino acids from its host's lungs. 2010 PLoS ONE pmid:21188143
Kubicek J et al. Controlled in meso phase crystallization--a method for the structural investigation of membrane proteins. 2012 PLoS ONE pmid:22536388
Shi T et al. cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. 2010 PLoS ONE pmid:20957031
Wise JK et al. Temporal gene expression profiling during rat femoral marrow ablation-induced intramembranous bone regeneration. 2010 PLoS ONE pmid:20957030
Pradhan RK et al. Characterization of membrane potential dependency of mitochondrial Ca2+ uptake by an improved biophysical model of mitochondrial Ca2+ uniporter. 2010 PLoS ONE pmid:20949039
Edwards TE et al. Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. 2010 PLoS ONE pmid:20862217
Hagopian K et al. Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice. 2010 PLoS ONE pmid:20856881
Sripadi P et al. Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry. 2010 PLoS ONE pmid:20830293
Granjon T et al. Structure-function relations in oxaloacetate decarboxylase complex. Fluorescence and infrared approaches to monitor oxomalonate and Na(+) binding effect. 2010 PLoS ONE pmid:20543879
Amoêdo ND et al. Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. 2011 PLoS ONE pmid:21789245
Gonzalvez F et al. Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin. 2010 PLoS ONE pmid:20179769
Zhao JS et al. Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation. 2010 PLoS ONE pmid:20174598
Smejkalová H et al. Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. 2010 PLoS ONE pmid:20957036
Hagemann TL et al. Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival. 2012 PLoS ONE pmid:22693571
Ferramosca A et al. A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats. 2012 PLoS ONE pmid:22685607
Chen JW et al. Phenotypic and transcriptomic response of auxotrophic Mycobacterium avium subsp. paratuberculosis leuD mutant under environmental stress. 2012 PLoS ONE pmid:22675497
Khodadad CL and Foster JS Metagenomic and metabolic profiling of nonlithifying and lithifying stromatolitic mats of Highborne Cay, The Bahamas. 2012 PLoS ONE pmid:22662280
Tomita Y et al. Genome and transcriptome analysis of the food-yeast Candida utilis. 2012 PLoS ONE pmid:22629373
Scalliet G et al. Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. 2012 PLoS ONE pmid:22536383
Xu XM et al. Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. 2009 PLoS ONE pmid:19865480
Wong YH et al. Involvement of Wnt signaling pathways in the metamorphosis of the bryozoan Bugula neritina. 2012 PLoS ONE pmid:22448242
Perrot O et al. Quantitative assessment of stereotyped and challenged locomotion after lesion of the striatum: a 3D kinematic study in rats. 2009 PLoS ONE pmid:19859550
Wang N et al. Changes in soybean global gene expression after application of lipo-chitooligosaccharide from Bradyrhizobium japonicum under sub-optimal temperature. 2012 PLoS ONE pmid:22348109
Gobert GN et al. Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. 2010 PLoS Negl Trop Dis pmid:20161728
Wu J et al. Metabolic changes reveal the development of schistosomiasis in mice. 2010 PLoS Negl Trop Dis pmid:20824219
Holder JW et al. Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development. 2011 PLoS Genet. pmid:21931557