Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sawai S et al. | Spontaneous symmetry breaking turing-type pattern formation in a confined Dictyostelium cell mass. | 2000 | Phys. Rev. Lett. | pmid:10970500 |
Aime S et al. | Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI. | 2000 | J. Biol. Inorg. Chem. | pmid:10968620 |
Li J and Copeland L | Role of malonate in chickpeas. | 2000 | Phytochemistry | pmid:10963451 |
Jung JW et al. | The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies. | 2000 | Protein Sci. | pmid:10933494 |
Dongmei H et al. | Synthesis and analgesic activity of N,N'-dicarbonyltryptamines. | 2000 | Prep. Biochem. Biotechnol. | pmid:10919562 |
Nath R et al. | Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10903889 |
Andreassen OA et al. | Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. | 2000 | J. Neurochem. | pmid:10899963 |
Koo HM and Kim YS | Identification of active-site residues in Bradyrhizobium japonicum malonyl-coenzyme A synthetase. | 2000 | Arch. Biochem. Biophys. | pmid:10871057 |
Kuijt J et al. | Quenched phosphorescence, a new detection method in capillary electrophoresis. | 2000 | Electrophoresis | pmid:10826674 |
Sett S et al. | Avirulent mutants of Macrophomina phaseolina and Aspergillus fumigatus initiate infection in Phaseolus mungo in the presence of phaseolinone; levamisole gives protection. | 2000 | J. Biosci. | pmid:10824201 |
Bew SP et al. | Kinetic resolution of alpha-acetoxy carboxylic acids with homochiral SuperQuats. | 2000 | Chirality | pmid:10824175 |
Lin LZ et al. | Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. membranaceus. | 2000 | J Chromatogr A | pmid:10823504 |
Guidetti P et al. | In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum. | 2000 | Exp. Neurol. | pmid:10785450 |
Moy LY et al. | Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures. | 2000 | J. Neurochem. | pmid:10737624 |
Uyemura SA et al. | Oxidative phosphorylation, Ca(2+) transport, and fatty acid-induced uncoupling in malaria parasites mitochondria. | 2000 | J. Biol. Chem. | pmid:10734123 |
Gougoux A et al. | Maleate-induced bicarbonaturia in the dog: a carbonic anhydrase-independene effect. | 1976 | Am. J. Physiol. | pmid:10734 |
Malcon C et al. | Neuroprotective effects of creatine administration against NMDA and malonate toxicity. | 2000 | Brain Res. | pmid:10727643 |
Malik N et al. | Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. | 2000 | J Control Release | pmid:10699277 |
Fitzgerald JW et al. | Reversal of succinate-mediated catabolite repression of alkylsulfatase in Pseudomonas aeruginosa by 2,4-dinitrophenol and by sodium malonate. | 1978 | Can. J. Microbiol. | pmid:106946 |
Kaal EC et al. | Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis. | 2000 | J. Neurochem. | pmid:10693948 |