Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lu GW et al. | Alteration of oxygen consumption and energy metabolism during repetitive exposure of mice to hypoxia. | 1999 | Neurochem. Res. | pmid:10344590 |
Chohnan S et al. | Cloning and characterization of mdc genes encoding malonate decarboxylase from Pseudomonas putida. | 1999 | FEMS Microbiol. Lett. | pmid:10339824 |
Matthews RT et al. | Novel free radical spin traps protect against malonate and MPTP neurotoxicity. | 1999 | Exp. Neurol. | pmid:10222114 |
Turnbull LB et al. | Excretion and biotransformation of carboxymethyl-cysteine in rat, dog, monkey and man. | 1978 | Xenobiotica | pmid:102086 |
Schulz JB et al. | Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. | 1998 | Cell Death Differ. | pmid:10203688 |
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