Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shama SA | Determination of the thermodynamic parameters and stability constants of UO2(2+), Th4+, and Ce3+ complexes with some azo-benzene-N-malonic acid derivatives. | 2001 May-Jun | Ann Chim | pmid:11507839 |
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Pecori Vettori L et al. | [Synthesis of derivatives of 4,9-dimethoxy-5-methyl-7H-furo-(3,2-g)-1-benzopyrano-6-carboxy-7-one]. | 1975 | Farmaco Sci | pmid:1157923 |
Xia XG et al. | Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation. | 2001 | J. Neurochem. | pmid:11595758 |
Reszko AE et al. | Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. | 2001 | Anal. Biochem. | pmid:11673897 |
pmid:11679290 | ||||
pmid:11681943 | ||||
pmid:11695919 | ||||
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Hardin CD et al. | Myocardial metabolism of exogenous FDP is consistent with transport by a dicarboxylate transporter. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11709435 |
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pmid:11740090 | ||||
Boismare F and Lorenzo J | Study of the protection on afforded by nicergoline against the effects of cerebral ischemia in the cat. | 1975 | Arzneimittelforschung | pmid:1174043 |
Brown SP and Spiess HW | Advanced solid-state NMR methods for the elucidation of structure and dynamics of molecular, macromolecular, and supramolecular systems. | 2001 | Chem. Rev. | pmid:11740929 |
pmid:11743956 | ||||
Marek M and Stuchl I | Synchronization in two interacting oscillatory systems. | 1975 | Biophys. Chem. | pmid:1174646 |
Marek M and Svobodová E | Nonlinear phenomena in oscillatory systems of homogeneous reactions - experimental observations. | 1975 | Biophys. Chem. | pmid:1174649 |
Reeves CD et al. | Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations. | 2001 | Biochemistry | pmid:11747421 |
Soong CL et al. | Barbiturase, a novel zinc-containing amidohydrolase involved in oxidative pyrimidine metabolism. | 2002 | J. Biol. Chem. | pmid:11748240 |
pmid:11764151 | ||||
Demin OV et al. | [Kinetic modeling of energy metabolism and generation of active forms of oxygen in hepatocyte mitochondria]. | 2001 Nov-Dec | Mol. Biol. (Mosk.) | pmid:11771135 |
pmid:11772081 | ||||
Gorrell A et al. | Determinants of L-aspartate and IMP recognition in Escherichia coli adenylosuccinate synthetase. | 2002 | J. Biol. Chem. | pmid:11781326 |
Ozcan C et al. | Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11788400 |
Janausch IG et al. | C4-dicarboxylate carriers and sensors in bacteria. | 2002 | Biochim. Biophys. Acta | pmid:11803016 |
Cecchini G et al. | Succinate dehydrogenase and fumarate reductase from Escherichia coli. | 2002 | Biochim. Biophys. Acta | pmid:11803023 |
Yang XL et al. | Photo-induced cytotoxicity of malonic acid [C(60)]fullerene derivatives and its mechanism. | 2002 | Toxicol In Vitro | pmid:11812638 |
pmid:11825076 | ||||
pmid:11841298 | ||||
Okun JG et al. | Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity. | 2002 | J. Biol. Chem. | pmid:11847233 |
pmid:11853511 | ||||
pmid:11866611 | ||||
Peddicord MB and Weber SG | Nonaqueous affinity capillary electrophoresis investigation of small molecule molecular recognition. | 2002 | Electrophoresis | pmid:11870744 |
pmid:11879800 | ||||
Dimroth P and Hilbi H | Enzymic and genetic basis for bacterial growth on malonate. | 1997 | Mol. Microbiol. | pmid:11902724 |
Nelson ME and Priestley ND | Nonactin biosynthesis: the initial committed step is the condensation of acetate (malonate) and succinate. | 2002 | J. Am. Chem. Soc. | pmid:11902879 |
Onisko BC et al. | Identification of fonofos metabolites in Latuca sativa, Beta vulgaris, and Triticum aestivum by packed capillary flow fast atom bombardment tandem mass spectrometry. | 2002 | J. Agric. Food Chem. | pmid:11902934 |
Hansen DS et al. | Direct identification and susceptibility testing of enteric bacilli from positive blood cultures using VITEK (GNI+/GNS-GA). | 2002 | Clin. Microbiol. Infect. | pmid:11906499 |
Janssen U and Stoffel W | Disruption of mitochondrial beta -oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse. | 2002 | J. Biol. Chem. | pmid:11916962 |
pmid:11924854 |