Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Karakikes I et al. | Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. | 2009 | PLoS ONE | pmid:19649297 |
Brown AK et al. | Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. | 2009 | PLoS ONE | pmid:19609444 |
Tiziani S et al. | Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. | 2009 | PLoS ONE | pmid:19158949 |
Seifert EL et al. | Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. | 2010 | PLoS ONE | pmid:20352092 |
Finley LW et al. | Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. | 2011 | PLoS ONE | pmid:21858060 |
Ruiz M et al. | A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | 2012 | PLoS ONE | pmid:23056435 |
Lin H et al. | The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. | 2011 | PLoS ONE | pmid:21552483 |
GarcÃa-Torres I et al. | Identification of amino acids that account for long-range interactions in two triosephosphate isomerases from pathogenic trypanosomes. | 2011 | PLoS ONE | pmid:21533154 |
Thomas B et al. | Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. | 2011 | PLoS ONE | pmid:21304957 |
Qi M et al. | Genome sequence analyses of Pseudomonas savastanoi pv. glycinea and subtractive hybridization-based comparative genomics with nine pseudomonads. | 2011 | PLoS ONE | pmid:21304594 |
Kubicek J et al. | Controlled in meso phase crystallization--a method for the structural investigation of membrane proteins. | 2012 | PLoS ONE | pmid:22536388 |
Kil DY et al. | Age and diet affect gene expression profiles in canine liver tissue. | 2010 | PLoS ONE | pmid:20967283 |
Shi T et al. | cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. | 2010 | PLoS ONE | pmid:20957031 |
Smejkalová H et al. | Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. | 2010 | PLoS ONE | pmid:20957036 |
Xiao L et al. | Transcriptome of protoplasts reprogrammed into stem cells in Physcomitrella patens. | 2012 | PLoS ONE | pmid:22545152 |
Scalliet G et al. | Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. | 2012 | PLoS ONE | pmid:22536383 |
Gueguen C et al. | Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition. | 2014 | PLoS ONE | pmid:24586272 |
Zuno-Floriano FG et al. | Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety. | 2012 | PLoS ONE | pmid:22363586 |
Fujii T and Albarède F | Ab initio calculation of the Zn isotope effect in phosphates, citrates, and malates and applications to plants and soil. | 2012 | PLoS ONE | pmid:22363478 |
Wang N et al. | Changes in soybean global gene expression after application of lipo-chitooligosaccharide from Bradyrhizobium japonicum under sub-optimal temperature. | 2012 | PLoS ONE | pmid:22348109 |