Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lançar-Benba J et al. | Purification of the rat-liver mitochondrial dicarboxylate carrier by affinity chromatography on immobilized malate dehydrogenase. | 1994 | Biochim. Biophys. Acta | pmid:8142418 |
Nikiforov AA and Ostretsova IB | Stimulation of weak organic acid uptake in rat renal tubules by cadmium and nystatin. | 1994 | Biochem. Pharmacol. | pmid:8135857 |
Tassani V et al. | Anaplerotic effect of propionyl carnitine in rat heart mitochondria. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8135845 |
Beattie DS et al. | Oxidation of NADH by a rotenone and antimycin-sensitive pathway in the mitochondrion of procyclic Trypanosoma brucei brucei. | 1994 | Mol. Biochem. Parasitol. | pmid:8078526 |
Henshaw R et al. | Malonate produces striatal lesions by indirect NMDA receptor activation. | 1994 | Brain Res. | pmid:8069700 |
Boland NI et al. | Characterization of follicular energy metabolism. | 1994 | Hum. Reprod. | pmid:8046010 |
Reiss U and Rothstein M | Age-related changes in isocitrate lyase from the free living nematode, Turbatrix aceti. | 1975 | J. Biol. Chem. | pmid:803500 |
Beal MF et al. | Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. | 1994 | Ann. Neurol. | pmid:7998775 |
Ray S et al. | Inhibition of electron flow through complex I of the mitochondrial respiratory chain of Ehrlich ascites carcinoma cells by methylglyoxal. | 1994 | Biochem. J. | pmid:7945267 |
Kim YS and Kim EJ | A plasmid responsible for malonate assimilation in Pseudomonas fluorescens. | 1994 | Plasmid | pmid:7846146 |