Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Winograd B et al. | Phase I study of ethylenediamine platinum(II) malonate (NSC 146 068), a second generation platinum analogue. | 1986 | Cancer Res. | pmid:3948186 |
Aoyama H et al. | Acute poisoning by intentional ingestion of thallous malonate. | 1986 | Hum Toxicol | pmid:3804358 |
Rawsthorne S and Larue TA | Metabolism under Microaerobic Conditions of Mitochondria from Cowpea Nodules. | 1986 | Plant Physiol. | pmid:16664950 |
Latipää PM et al. | Regulation of palmitoylcarnitine oxidation in isolated rat liver mitochondria. Role of the redox state of NAD(H). | 1986 | Biochim. Biophys. Acta | pmid:3002483 |
Brown GC and Brand MD | Changes in permeability to protons and other cations at high proton motive force in rat liver mitochondria. | 1986 | Biochem. J. | pmid:3010957 |
Beavis AD and Lehninger AL | The upper and lower limits of the mechanistic stoichiometry of mitochondrial oxidative phosphorylation. Stoichiometry of oxidative phosphorylation. | 1986 | Eur. J. Biochem. | pmid:3015613 |
Hederstedt L and Hatefi Y | Modification of bovine heart succinate dehydrogenase with ethoxyformic anhydride and rose bengal: evidence for essential histidyl residues protectable by substrates. | 1986 | Arch. Biochem. Biophys. | pmid:3717948 |
Kaplan RS and Pedersen PL | Isolation and reconstitution of the n-butylmalonate-sensitive dicarboxylate transporter from rat liver mitochondria. | 1985 | J. Biol. Chem. | pmid:4019514 |
Zell A et al. | Model for calcium binding to gamma-carboxyglutamic acid residues of proteins: crystal structure of calcium alpha-ethylmalonate. | 1985 | Biochemistry | pmid:3978091 |
Affranchino JL et al. | Respiratory control in mitochondria from Trypanosoma cruzi. | 1985 | Mol. Biochem. Parasitol. | pmid:3903495 |
Ullrich KJ et al. | Contraluminal sulfate transport in the proximal tubule of the rat kidney. III. Specificity: disulfonates, di- and tri-carboxylates and sulfocarboxylates. | 1985 | Pflugers Arch. | pmid:4059021 |
Bourke E et al. | Effects of inhibitors of the tricarboxylic acid cycle on glutamine utilization in the intact dog kidney. Renal glutamine utilization following TCA cycle blockade. | 1985 | Contrib Nephrol | pmid:4064698 |
Zoratti M and Petronilli V | Multiple relationships between rate of oxidative phosphorylation and delta microH in rat liver mitochondria. | 1985 | FEBS Lett. | pmid:4065342 |
Saint-Macary M and Foucher B | Comparative partial purification of the active dicarboxylate transport system of rat liver, kidney and heart mitochondria. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084286 |
Andrews PA et al. | Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion. | 1985 | Cancer Res. | pmid:4063975 |
Kim YS and Bang SK | Malonyl coenzyme A synthetase. Purification and properties. | 1985 | J. Biol. Chem. | pmid:3921541 |
Mikkelsen J et al. | Stoichiometry of substrate binding to rat liver fatty acid synthetase. | 1985 | Biochem. J. | pmid:4052054 |
Brooks CA et al. | Salicylhydroxamic acid potentiates germination of 'Waldmann's Green' lettuce seed. | 1985 | Plant Physiol. | pmid:11540836 |
Catia Sorgato M et al. | Partial uncoupling, or inhibition of electron transport rate, have equivalent effects on the relationship between the rate of ATP synthesis and proton-motive force in submitochondrial particles. | 1985 | FEBS Lett. | pmid:2982663 |
Marzulli D et al. | N-ethylmaleimide as oxidizing agent in biological and non-biological systems. | 1985 | Boll. Soc. Ital. Biol. Sper. | pmid:2983741 |
Dry IB and Wiskich JT | Inhibition of 2-oxoglutarate oxidation in plant mitochondria by pyruvate. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084285 |
Donaldson WE | Biotin effects on fatty acid synthesis in chicks. | 1985 | Ann. N. Y. Acad. Sci. | pmid:2861776 |
Scaduto RC and Schoolwerth AC | Effect of bicarbonate on glutamine and glutamate metabolism by rat kidney cortex mitochondria. | 1985 | Am. J. Physiol. | pmid:2864861 |
Seren S et al. | Current-voltage relationships for proton flow through the F0 sector of the ATP-synthase, carbonylcyanide-p-trifluoromethoxyphenylhydrazone or leak pathways in submitochondrial particles. | 1985 | Eur. J. Biochem. | pmid:2865136 |
Brown-Woodman PD et al. | Effects of malonic, maleic, citric and caffeic acids on the motility of human sperm and penetration of cervical mucus. | 1985 | Int. J. Fertil. | pmid:2867056 |
Müller SC et al. | The structure of the core of the spiral wave in the belousov-zhabotinskii reaction. | 1985 | Science | pmid:17797290 |
Vitorica J et al. | Impairment of glutamate uptake and absence of alterations in the energy-transducing ability of old rat brain mitochondria. | 1985 | Mech. Ageing Dev. | pmid:2985886 |
Woelders H et al. | The phosphate potential maintained by mitochondria in State 4 is proportional to the proton-motive force. | 1985 | FEBS Lett. | pmid:2981706 |
Vayer P et al. | Conversion of gamma-hydroxybutyrate to gamma-aminobutyrate in vitro. | 1985 | J. Neurochem. | pmid:2863327 |
Nefelova MV et al. | [Nonactin biosynthesis. The incorporation of precursors into the antibiotic molecule]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:3840667 |
Krausse R and Ullmann U | Studies on the identification of Campylobacter species using biochemical tests and high-performance liquid chromatography. | 1985 | Zentralbl Bakteriol Mikrobiol Hyg A | pmid:3911663 |
Affranchino JL and Stoppani AO | [Existence of 2 sites of oxidative phosphorylation in Trypanosoma cruzi]. | 1985 | Rev. Argent. Microbiol. | pmid:3916670 |
Stefancich G et al. | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-quinoline-3-carb oxylic acid, a new fluorinated compounds of oxacin family with high broad-spectrum antibacterial activities. | 1985 | Farmaco Sci | pmid:3926533 |
Ferchichi M et al. | Production of methanethiol from methionine by Brevibacterium linens CNRZ 918. | 1985 | J. Gen. Microbiol. | pmid:3989511 |
Svanas GW and Weiner H | Enzymatic requirement for cyanamide inactivation of rat liver aldehyde dehydrogenase. | 1985 | Biochem. Pharmacol. | pmid:3994742 |
Oliver DJ and Walker GH | Characterization of the transport of oxaloacetate by pea leaf mitochondria. | 1984 | Plant Physiol. | pmid:16663855 |
Khalifah RG and Morley PJ | A carbon-13 NMR comparative study of metal ion substitutions in human carbonic anhydrase I carboxymethylated at active-site histidine-200. | 1984 | Arch. Biochem. Biophys. | pmid:6431907 |
Crossin MC et al. | Perturbation of ribosome subunit interaction by glutaraldehyde fixation. | 1984 | Biophys. Chem. | pmid:6435698 |
Kalckar HM and Ullrey DB | Hexose uptake regulation mediated through aerobic pathways: schism in a fibroblast mutant. | 1984 | Fed. Proc. | pmid:6538853 |
Robinet D et al. | Separation of haemoglobins using a monodisperse cation exchanger. | 1984 | J. Chromatogr. | pmid:6490765 |
Matern U et al. | N-malonyltransferases from peanut. | 1984 | Arch. Biochem. Biophys. | pmid:6497391 |
Boquist L | Alloxan effects on mitochondria: study of oxygen consumption, fluxes of Mg2+, Ca2+, K+ and adenine nucleotides, membrane potential and volume change in vitro. | 1984 | Diabetologia | pmid:6500198 |
Lebedev OE et al. | [Inhibitory analysis of the functions of the oxidative metabolic systems of tumor cells in tissue culture]. | 1984 | Tsitologiia | pmid:6474574 |
Kotlyar AB and Vinogradov AD | Evidence for an essential arginine residue in the substrate binding site of the mammalian succinate dehydrogenase. | 1984 | Biochem. Int. | pmid:6477618 |
Chen SC | Fluorometric determination of malonic acid with dicyclohexylcarbodiimide. | 1984 | Anal. Biochem. | pmid:6486406 |
Long SD et al. | Succinate dehydrogenase in various tissues of Anodonta couperiana, Elliptio buckleyi and Mercenaria campechiensis (Mollusca: Bivalvia). | 1984 | Comp. Biochem. Physiol., B | pmid:6467909 |
van der Vijgh WJ et al. | Determination of ethylenediamineplatinum(II) malonate in infusion fluids, human plasma and urine by high-performance liquid chromatography. | 1984 | J. Chromatogr. | pmid:6511851 |
Kok WT et al. | Determination of oxalic acid in biological matrices by liquid chromatography with amperometric detection. | 1984 | J. Chromatogr. | pmid:6526899 |
Lenartowicz E and Savina MV | Intramitochondrial reductive carboxylation of 2-oxoglutarate in adipose tissue and its contribution to fatty acid synthesis. | 1984 | Int. J. Biochem. | pmid:6530009 |
Ficsor G et al. | Comparison of methods for detecting mitomycin C- and ethyl nitrosourea-induced germ cell damage in mice: sperm enzyme activities, sperm motility, and testis weight. | 1984 | Environ Mutagen | pmid:6428870 |
Mitzen EJ and Koeppen AH | Malonate, malonyl-coenzyme A, and acetyl-coenzyme A in developing rat brain. | 1984 | J. Neurochem. | pmid:6429279 |
Kotlyar AB and Vinogradov AD | Interaction of the membrane-bound succinate dehydrogenase with substrate and competitive inhibitors. | 1984 | Biochim. Biophys. Acta | pmid:6691982 |
Russell JB and Van Soest PJ | In vitro ruminal fermentation of organic acids common in forage. | 1984 | Appl. Environ. Microbiol. | pmid:6696413 |
Huber KW and Lutz WK | Methylation of DNA by incubation with methylamine and nitrite. | 1984 | Carcinogenesis | pmid:6705144 |
Sagi SR et al. | Thallimetric oxidations-IV Estimation of malonic acid. | 1984 | Talanta | pmid:18963570 |
Ito E et al. | Effects of 2,4-dinitrophenol and other metabolic inhibitors on the thermograms of Ehrlich ascites carcinoma cells registered with a microcalorimeter. | 1984 | Cancer Res. | pmid:6713397 |
Brown GK et al. | Malonyl coenzyme A decarboxylase deficiency. | 1984 | J. Inherit. Metab. Dis. | pmid:6145813 |
Ksenzenko M et al. | Relationships between the effects of redox potential, alpha-thenoyltrifluoroacetone and malonate on O(2) and H2O2 generation by submitochondrial particles in the presence of succinate and antimycin. | 1984 | FEBS Lett. | pmid:6090204 |
Huang EM et al. | Succinate potentiates the action of platelet agonists. | 1984 | Thromb. Res. | pmid:6095483 |
Williams WL et al. | Indirect inactivation of rabbit reticulocyte initiation factor eIF-2 by helenalin and bis(helenalinyl) malonate. | 1984 | Biochemistry | pmid:6095903 |
Duszyński J et al. | Homeostasis of the protonmotive force in phosphorylating mitochondria. | 1984 | Biochim. Biophys. Acta | pmid:6095904 |
Wingrove DE et al. | Glucagon effects on the membrane potential and calcium uptake rate of rat liver mitochondria. | 1984 | J. Biol. Chem. | pmid:6204980 |
Costa LE et al. | Stoichiometry of mitochondrial H+ translocation coupled to succinate oxidation at level flow. | 1984 | J. Biol. Chem. | pmid:6232269 |
Nakae Y and Shono M | Kinetic behaviour of succinate dehydrogenase of three fibre types in skeletal muscle. I. Effects of temperature and a competitive inhibitor. | 1984 | Histochem. J. | pmid:6210273 |
Kotliar AB and Vinogradov AD | [Interaction of succinate dehydrogenase and oxaloacetate]. | 1984 | Biokhimiia | pmid:6733163 |
Abraham DJ et al. | Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. | 1984 | J. Med. Chem. | pmid:6747995 |
Yagi T et al. | Modulation of the kinetics and the steady-state level of intermediates of mitochondrial coupled reactions by inhibitors and uncouplers. | 1984 | Biochemistry | pmid:6712922 |
Kotliar AB and Vinogradov AD | [Dissociation constants of succinate dehydrogenase complexes with succinate, fumarate and malonate]. | 1984 | Biokhimiia | pmid:6722218 |
Wozniak AJ et al. | Inhibition of etoposide-induced DNA damage and cytotoxicity in L1210 cells by dehydrogenase inhibitors and other agents. | 1984 | Cancer Res. | pmid:6318974 |
Dahl KH and Dunn MF | Carboxymethylated liver alcohol dehydrogenase: kinetic and thermodynamic characterization of reactions with substrates and inhibitors. | 1984 | Biochemistry | pmid:6397230 |
Mandrik KA et al. | [Kinetics of the inhibition of succinate dehydrogenase in bull adrenal cortex by malonate and oxaloacetate]. | 1983 Sep-Oct | Ukr. Biokhim. Zh. | pmid:6636310 |
Chappell J and Beevers H | Transport of dicarboxylic acids in castor bean mitochondria. | 1983 | Plant Physiol. | pmid:16663021 |
Reibach PH and Streeter JG | Metabolism of C-labeled photosynthate and distribution of enzymes of glucose metabolism in soybean nodules. | 1983 | Plant Physiol. | pmid:16663058 |
Kennedy RA et al. | Germination of Echinochloa crus-galli (Barnyard Grass) Seeds under Anaerobic Conditions : Respiration and Response to Metabolic Inhibitors. | 1983 | Plant Physiol. | pmid:16663086 |
Davis LC and Nordin P | Sugar and organic Acid constituents in white clover. | 1983 | Plant Physiol. | pmid:16663119 |
Mukherjee KD | Lipid biosynthesis in developing mustard seed: formation of triacylglycerols from endogenous and exogenous Fatty acids. | 1983 | Plant Physiol. | pmid:16663345 |
Godbole SS et al. | Immobilization of fumarase by entrapment of rat liver mitochondria in polyacrylamide gel using gamma rays. | 1983 | Biotechnol. Bioeng. | pmid:18548549 |
Tallitsch RB | Further observations of aldosterone response in barnacle muscle fibers. | 1983 | Am. J. Physiol. | pmid:6614162 |
Tomaszewska B et al. | Phosphoenolpyruvate carboxylase from the roots of yellow lupin (Lupinus luteus). | 1983 | Acta Biochim. Pol. | pmid:6673422 |
Hegardt FG et al. | Inactivation of rat liver HMG-CoA reductase phosphatases by polycarboxylic acids. | 1983 | J. Lipid Res. | pmid:6631216 |
Ogawa H et al. | Xanthommatin formation in rat liver mitochondria and its inhibition by respiratory chain substrates. | 1983 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6662501 |
Hansen TL and Andersen H | Succinate dehydrogenase activity in cultured human skin fibroblasts and amniotic fluid cells. A methodological study. | 1983 | Histochemistry | pmid:6874423 |
Cutbush SD et al. | The antitumor complex ethylenediamine platinum (II) malonate: x-ray structure analysis, and studies of its stability in solution. | 1983 | J. Inorg. Biochem. | pmid:6875536 |
Bonomi F et al. | Modification of the thermodynamic properties of the electron-transferring groups in mitochondrial succinate dehydrogenase upon binding of succinate. | 1983 | Eur. J. Biochem. | pmid:6884342 |
Liou YF et al. | Investigation of sesquiterpene lactones as protein synthesis inhibitors of P-388 lymphocytic leukemia cells. | 1983 | Biochim. Biophys. Acta | pmid:6824673 |
Wanders RJ et al. | Bicarbonate and the pathway of glutamate oxidation in isolated rat-liver mitochondria. | 1983 | Eur. J. Biochem. | pmid:6852031 |
Chorev M and Goodman M | Partially modified retro-inverso peptides. Comparative Curtius rearrangements to prepare 1,1-diaminoalkane derivatives. | 1983 | Int. J. Pept. Protein Res. | pmid:6853027 |
Saint-Macary M and Foucher B | Reconstitution of the dicarboxylate exchange activity by incorporation into liposomes of a Triton-extract of mitochondrial rat-liver inner membranes. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6860337 |
Matern U | Acylhydrolases from parsley (Petroselinum hortense). Relative distribution and properties of four esterases hydrolyzing malonic acid hemiesters of flavonoid glucosides. | 1983 | Arch. Biochem. Biophys. | pmid:6870256 |
LaNoue KF et al. | Ammonia formation in isolated rat liver mitochondria. | 1983 | J. Biol. Chem. | pmid:6130094 |
Schoolwerth AC et al. | Glutamate transprot in rat kidney mitochondria. | 1983 | J. Biol. Chem. | pmid:6130095 |
Matern U et al. | Conformational changes of apigenin 7-O-(6-O-malonylglucoside), a vacuolar pigment from parsley, with solvent composition and proton concentration. | 1983 | Eur. J. Biochem. | pmid:6303788 |
Ainscough EW et al. | Spectroscopic studies on copper (II) complexes of human lactoferrin. | 1983 | J. Inorg. Biochem. | pmid:6304246 |
Simpson DP | Citrate excretion: a window on renal metabolism. | 1983 | Am. J. Physiol. | pmid:6338740 |
Christopherson RI et al. | Chorismate mutase-prephenate dehydrogenase from Escherichia coli: spatial relationship of the mutase and dehydrogenase sites. | 1983 | Biochemistry | pmid:6342665 |
Lenzen S and Panten U | Characterization of succinate dehydrogenase and alpha-glycerophosphate dehydrogenase in pancreatic islets. | 1983 | Biochem Med | pmid:6360162 |
Wan AS et al. | Long-acting contraceptive agents: levonorgestrel esters of unsaturated acids. | 1983 | Steroids | pmid:6419407 |
Yamaguchi M et al. | Role of zinc as an activator of mitochondrial function in rat liver. | 1982 | Biochem. Pharmacol. | pmid:6212062 |
Decoux G et al. | [Rapid method for the determination of urinary oxalic acid by gas liquid chromatography (author's transl)]. | 1982 | Clin. Chim. Acta | pmid:7067145 |
Fioravanti CF | Mitochondrial NADH oxidase activity of adult Hymenolepis diminuta (Cestoda). | 1982 | Comp. Biochem. Physiol., B | pmid:7128112 |