Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ermayanti TM et al. | Stimulation of synthesis and release of swainosonine from transformed roots of Swainsona galegifolia. | 1994 | Phytochemistry | pmid:7764877 |
Klein BY et al. | Analysis of cell-mediated mineralization in culture of bone-derived embryonic cells with neurofibromatosis. | 1995 | J. Cell. Biochem. | pmid:7768987 |
Kirschner PB et al. | Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats. | 1995 | J. Cereb. Blood Flow Metab. | pmid:7790410 |
Nieva-Gomez D and Konisky J | Membrane changes in Escherichia coli induced by colicin Ia and agents known to disrupt energy transduction. | 1976 | Biochemistry | pmid:779829 |
Oldendorf WH et al. | Transient blood-brain barrier passage of polar compounds at low pH. | 1994 | Am. J. Physiol. | pmid:7810722 |
Brand MD et al. | The sum of flux control coefficients in the electron-transport chain of mitochondria. | 1994 | Eur. J. Biochem. | pmid:7813471 |
Kim YS and Kim EJ | A plasmid responsible for malonate assimilation in Pseudomonas fluorescens. | 1994 | Plasmid | pmid:7846146 |
Ray S et al. | Inhibition of electron flow through complex I of the mitochondrial respiratory chain of Ehrlich ascites carcinoma cells by methylglyoxal. | 1994 | Biochem. J. | pmid:7945267 |
Beal MF et al. | Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. | 1994 | Ann. Neurol. | pmid:7998775 |
Reiss U and Rothstein M | Age-related changes in isocitrate lyase from the free living nematode, Turbatrix aceti. | 1975 | J. Biol. Chem. | pmid:803500 |