Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Schurr A and Gozal E | Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress. | 2011 | Front Pharmacol | pmid:22275901 |
Roth S | Mathematics and biology: a Kantian view on the history of pattern formation theory. | 2011 | Dev. Genes Evol. | pmid:22086125 |
Holley AK et al. | Manganese superoxide dismutase: guardian of the powerhouse. | 2011 | Int J Mol Sci | pmid:22072939 |
Padalkar VS et al. | Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding. | 2011 | Chem Cent J | pmid:22067202 |
Li Z | 4,4'-[p-Phenyl-enebis(-oxy)]dibutanoic acid. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22065827 |
Guo HM | 6-Benzyl 4-ethyl 2-chloro-5,6,7,8-tetra-hydro-pyrido[4,3-d]pyrimidine-4,6-di-carboxyl-ate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22065115 |
Deng YF | Poly[[[μ(3)-5-(pyridine-4-carboxamido)-isophthalato]{μ(3)-5-[(pyridin-1-ium-4-yl)carbonyl-amino]-isophthalato}-neodymium(III)] dihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22058886 |
Jose DA et al. | Allosteric Pâ•O-based receptors for dicarboxylic acids. | 2011 | Org. Lett. | pmid:21667961 |
Hanif M et al. | From hydrolytically labile to hydrolytically stable Ru(II)-arene anticancer complexes with carbohydrate-derived co-ligands. | 2011 | J. Inorg. Biochem. | pmid:21194622 |
Wolfenden R et al. | Kinetic challenges facing oxalate, malonate, acetoacetate, and oxaloacetate decarboxylases. | 2011 | J. Am. Chem. Soc. | pmid:21434608 |
Sivananthan SN and Leavitt BR | Cystamine and ethyl-eicosapentaenoic acid treatment fail to prevent malonate-induced striatal toxicity in mice. | 2011 | Neurobiol. Aging | pmid:21741126 |
Ghorai S et al. | Spectroscopic evidence of keto-enol tautomerism in deliquesced malonic acid particles. | 2011 | J Phys Chem A | pmid:21480651 |
Lafrance D et al. | Mild decarboxylative activation of malonic acid derivatives by 1,1'-carbonyldiimidazole. | 2011 | Org. Lett. | pmid:21488674 |
Beyer KD et al. | Phase diagrams and water activities of aqueous ammonium salts of malonic acid. | 2011 | J Phys Chem A | pmid:21428389 |
Barderas MG et al. | Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases. | 2011 | J. Biomed. Biotechnol. | pmid:21274272 |
Qiu G et al. | Efficient assembly of 1-(1H-imidazol-1-yl)-3-methylene-1H-indenes via tandem reaction of (2-(alkynyl)benzylidene)malonates with imidazoles. | 2011 | ACS Comb Sci | pmid:21247119 |
Lau SK et al. | Transport genes and chemotaxis in Laribacter hongkongensis: a genome-wide analysis. | 2011 | Cell Biosci | pmid:21849034 |
Sun D et al. | Diethyl 2-{4-diethyl-amino-2-[(dimethyl-carbamothio-yl)-oxy]benzyl-idene}malonate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21837219 |
Ranjith S et al. | Diethyl 2-{[3-(2-meth-oxy-benz-yl)thio-phen-2-yl]methyl-idene}malonate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21837085 |
Zhou H et al. | Poly[[aqua-tris-(μ-benzene-1,4-dicarboxyl-ato)tricobalt(II)] methanol monosolvate monohydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836846 |
Jeong YS et al. | Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. | 2011 | PLoS ONE | pmid:21811631 |
Li N et al. | Experimental Study of Closed System in the Chlorine Dioxide-Iodide-Sulfuric Acid Reaction by UV-Vis Spectrophotometric Method. | 2011 | Int J Anal Chem | pmid:21808646 |
Rogers GW et al. | High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. | 2011 | PLoS ONE | pmid:21799747 |
Garcia-Fernandez M et al. | Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats. | 2011 | J Transl Med | pmid:21798010 |
Lin H et al. | The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. | 2011 | PLoS ONE | pmid:21552483 |
Ghasemzadeh A and Jaafar HZ | Effect of CO(2) enrichment on synthesis of some primary and secondary metabolites in ginger (Zingiber officinale Roscoe). | 2011 | Int J Mol Sci | pmid:21541046 |
GarcÃa-Torres I et al. | Identification of amino acids that account for long-range interactions in two triosephosphate isomerases from pathogenic trypanosomes. | 2011 | PLoS ONE | pmid:21533154 |
Kalaitzis JA et al. | Policing starter unit selection of the enterocin type II polyketide synthase by the type II thioesterase EncL. | 2011 | Bioorg. Med. Chem. | pmid:21531566 |
Zeng WL | 2,2-Dimethyl-5-[(5-methyl-furan-2-yl)methyl-idene]-1,3-dioxane-4,6-dione. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21523135 |
Zeng WL | 3-(4-Bromo-benzyl-idene)-1,5-dioxaspiro-[5.5]undecane-2,4-dione. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21523094 |
Zeng WL | 3-(4-Fluoro-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522968 |
Aghabozorg H et al. | Bis(2-amino-4-methyl-pyridinium) bis-(pyridine-2,6-dicarboxyl-ato)cuprate(II). | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522859 |
Zhao YY | catena-Poly[[diaqua-cobalt(II)]-μ-4,4'-[1,4-phenyl-enebis(-oxy)]dibutano-ato-κO,O':O'',O''']. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522824 |
Lackner G et al. | Evolution of an endofungal lifestyle: Deductions from the Burkholderia rhizoxinica genome. | 2011 | BMC Genomics | pmid:21539752 |
Qi M et al. | Genome sequence analyses of Pseudomonas savastanoi pv. glycinea and subtractive hybridization-based comparative genomics with nine pseudomonads. | 2011 | PLoS ONE | pmid:21304594 |
Kim J and Winfree E | Synthetic in vitro transcriptional oscillators. | 2011 | Mol. Syst. Biol. | pmid:21283141 |
Wissler L et al. | Back to the sea twice: identifying candidate plant genes for molecular evolution to marine life. | 2011 | BMC Evol. Biol. | pmid:21226908 |
Facchinelli F and Weber AP | The metabolite transporters of the plastid envelope: an update. | 2011 | Front Plant Sci | pmid:22645538 |
Sloan JL et al. | Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria. | 2011 | Nat. Genet. | pmid:21841779 |
Kolaj-Robin O et al. | Biochemical and biophysical characterization of succinate: quinone reductase from Thermus thermophilus. | 2011 | Biochim. Biophys. Acta | pmid:20951673 |
Alfares A et al. | Combined malonic and methylmalonic aciduria: exome sequencing reveals mutations in the ACSF3 gene in patients with a non-classic phenotype. | 2011 | J. Med. Genet. | pmid:21785126 |
Witkowski A et al. | Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis. | 2011 | J. Biol. Chem. | pmid:21846720 |
Tyson T et al. | Functional and highly porous scaffolds for biomedical applications. | 2011 | Macromol Biosci | pmid:21842506 |
Eshkourfu R et al. | Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide. | 2011 | J. Inorg. Biochem. | pmid:21722616 |
Liu J et al. | Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. | 2011 | Int J Mol Sci | pmid:22072900 |
Bräutigam A et al. | An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species. | 2011 | Plant Physiol. | pmid:20543093 |
Menes RJ et al. | Halomonas vilamensis sp. nov., isolated from high-altitude Andean lakes. | 2011 | Int. J. Syst. Evol. Microbiol. | pmid:20584819 |
Amoêdo ND et al. | Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. | 2011 | PLoS ONE | pmid:21789245 |
Li JV et al. | Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections. | 2011 | Am. J. Trop. Med. Hyg. | pmid:21212208 |
Ates O et al. | Genome-scale reconstruction of metabolic network for a halophilic extremophile, Chromohalobacter salexigens DSM 3043. | 2011 | BMC Syst Biol | pmid:21251315 |