Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kim YS and Lee JK | Evidence that two covalent intermediates, phosphoryl and malonyl enzymes, are formed during malonyl-coenzyme A synthetase catalysis. | 1986 | J. Biol. Chem. | pmid:3097006 |
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pmid:29311556 | ||||
Hall IH et al. | Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones. | 1988 Jan-Feb | Anticancer Res. | pmid:2895992 |
Koeppen AH and Riley KM | Effect of free malonate on the utilization of glutamate by rat brain mitochondria. | 1987 | J. Neurochem. | pmid:2881982 |
pmid:28777873 | ||||
Zoratti M et al. | ATP synthase-mediated proton fluxes and phosphorylation in rat liver mitochondria: dependence on delta mu H. | 1986 | Biochim. Biophys. Acta | pmid:2873837 |
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Brown-Woodman PD et al. | Effects of malonic, maleic, citric and caffeic acids on the motility of human sperm and penetration of cervical mucus. | 1985 | Int. J. Fertil. | pmid:2867056 |
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