Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Edema D004487 152 associated lipids
Hemolysis D006461 131 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Brain Ischemia D002545 89 associated lipids
Alzheimer Disease D000544 76 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Parkinson Disease D010300 53 associated lipids
Nerve Degeneration D009410 53 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Nervous System Diseases D009422 37 associated lipids
Fever D005334 35 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Memory Disorders D008569 33 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Catalepsy D002375 30 associated lipids
Brain Diseases D001927 27 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Bacterial Infections D001424 21 associated lipids
Hyperglycemia D006943 21 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Brain Edema D001929 20 associated lipids
Ischemia D007511 18 associated lipids
Abscess D000038 13 associated lipids
Neoplasms D009369 13 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Teratoma D013724 4 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Neoplasms, Muscle Tissue D009379 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Holley AK et al. Manganese superoxide dismutase: guardian of the powerhouse. 2011 Int J Mol Sci pmid:22072939
Wolfenden R et al. Kinetic challenges facing oxalate, malonate, acetoacetate, and oxaloacetate decarboxylases. 2011 J. Am. Chem. Soc. pmid:21434608
Ghorai S et al. Spectroscopic evidence of keto-enol tautomerism in deliquesced malonic acid particles. 2011 J Phys Chem A pmid:21480651
Lafrance D et al. Mild decarboxylative activation of malonic acid derivatives by 1,1'-carbonyldiimidazole. 2011 Org. Lett. pmid:21488674
Beyer KD et al. Phase diagrams and water activities of aqueous ammonium salts of malonic acid. 2011 J Phys Chem A pmid:21428389
Barderas MG et al. Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases. 2011 J. Biomed. Biotechnol. pmid:21274272
Ranjith S et al. Diethyl 2-{[3-(2-meth-oxy-benz-yl)thio-phen-2-yl]methyl-idene}malonate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21837085
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Jeong YS et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. 2011 PLoS ONE pmid:21811631
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Kalaitzis JA et al. Policing starter unit selection of the enterocin type II polyketide synthase by the type II thioesterase EncL. 2011 Bioorg. Med. Chem. pmid:21531566
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Kolaj-Robin O et al. Biochemical and biophysical characterization of succinate: quinone reductase from Thermus thermophilus. 2011 Biochim. Biophys. Acta pmid:20951673
Eshkourfu R et al. Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide. 2011 J. Inorg. Biochem. pmid:21722616
Liu J et al. Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. 2011 Int J Mol Sci pmid:22072900
Menes RJ et al. Halomonas vilamensis sp. nov., isolated from high-altitude Andean lakes. 2011 Int. J. Syst. Evol. Microbiol. pmid:20584819
Ates O et al. Genome-scale reconstruction of metabolic network for a halophilic extremophile, Chromohalobacter salexigens DSM 3043. 2011 BMC Syst Biol pmid:21251315