Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:20681687 | ||||
| Balk M et al. | (Per)chlorate reduction by an acetogenic bacterium, Sporomusa sp., isolated from an underground gas storage. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20680263 |
| pmid:20680195 | ||||
| pmid:20678924 | ||||
| pmid:20672844 | ||||
| Ojha B et al. | 2-Alkylmalonic acid: amphiphilic chelator and a potent inhibitor of metalloenzyme. | 2010 | J Phys Chem B | pmid:20669918 |
| Bordel S et al. | Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes. | 2010 | PLoS Comput. Biol. | pmid:20657658 |
| pmid:20652202 | ||||
| Chakraborty B et al. | Stage specific developmental changes in the mitochondrial and surface membrane associated redox systems of Leishmania donovani promastigote and amastigote. | 2010 | Biochemistry Mosc. | pmid:20618140 |
| Bujacz G et al. | Cryoprotection properties of salts of organic acids: a case study for a tetragonal crystal of HEW lysozyme. | 2010 | Acta Crystallogr. D Biol. Crystallogr. | pmid:20606259 |
| George GM et al. | Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. | 2010 | Plant Physiol. | pmid:20605913 |
| pmid:20603552 | ||||
| pmid:20603179 | ||||
| Blum Y et al. | A factor model to analyze heterogeneity in gene expression. | 2010 | BMC Bioinformatics | pmid:20598132 |
| Chen AM et al. | Identification of a TRAP transporter for malonate transport and its expression regulated by GtrA from Sinorhizobium meliloti. | 2010 | Res. Microbiol. | pmid:20594941 |
| Gawarammana I et al. | Fructose-1, 6-diphosphate (FDP) as a novel antidote for yellow oleander-induced cardiac toxicity: a randomized controlled double blind study. | 2010 | BMC Emerg Med | pmid:20587052 |
| Menes RJ et al. | Halomonas vilamensis sp. nov., isolated from high-altitude Andean lakes. | 2011 | Int. J. Syst. Evol. Microbiol. | pmid:20584819 |
| Hullatti KK and Sharada MS | Comparative phytochemical investigation of the sources of ayurvedic drug patha: a chromatographic fingerprinting analysis. | 2010 | Indian J Pharm Sci | pmid:20582188 |
| Connor SC et al. | Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010 | Mol Biosyst | pmid:20567778 |
| Rellán-Alvarez R et al. | Changes in the proteomic and metabolic profiles of Beta vulgaris root tips in response to iron deficiency and resupply. | 2010 | BMC Plant Biol. | pmid:20565974 |
| Blaquiere N et al. | Decarboxylative ketone aldol reactions: development and mechanistic evaluation under metal-free conditions. | 2009 | J. Org. Chem. | pmid:20560569 |
| pmid:20544094 | ||||
| Granjon T et al. | Structure-function relations in oxaloacetate decarboxylase complex. Fluorescence and infrared approaches to monitor oxomalonate and Na(+) binding effect. | 2010 | PLoS ONE | pmid:20543879 |
| Bräutigam A et al. | An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species. | 2011 | Plant Physiol. | pmid:20543093 |
| Kamga CK et al. | Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria. | 2010 | Am. J. Physiol., Cell Physiol. | pmid:20538765 |
| Chattopadhyay K et al. | Mechanistic origin of the stereodivergence in decarboxylative allylation. | 2010 | Org. Lett. | pmid:20533852 |
| Kokubo K et al. | Synthesis and regiochemistry of [60]fullerenyl 2-methylmalonate bisadducts and their facile electron-accepting properties. | 2010 | J. Org. Chem. | pmid:20524640 |
| Jay D et al. | Study of the interaction of cadmium with membrane-bound succinate dehydrogenase. | 1991 | J. Bioenerg. Biomembr. | pmid:2050657 |
| Maertens B et al. | Gene optimization mechanisms: a multi-gene study reveals a high success rate of full-length human proteins expressed in Escherichia coli. | 2010 | Protein Sci. | pmid:20506237 |
| Yadav AV et al. | Co-crystals: a novel approach to modify physicochemical properties of active pharmaceutical ingredients. | 2009 | Indian J Pharm Sci | pmid:20502540 |
| Wanders RJ et al. | The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. | 2010 | J. Inherit. Metab. Dis. | pmid:20490924 |
| Taghavi S et al. | Genome sequence of the plant growth promoting endophytic bacterium Enterobacter sp. 638. | 2010 | PLoS Genet. | pmid:20485560 |
| Kellmann R et al. | Biosynthesis and molecular genetics of polyketides in marine dinoflagellates. | 2010 | Mar Drugs | pmid:20479965 |
| pmid:20470251 | ||||
| pmid:20452633 | ||||
| pmid:20449464 | ||||
| pmid:20449431 | ||||
| pmid:20449105 | ||||
| pmid:20449083 | ||||
| Chhabra S et al. | Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus. | 2010 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:20445263 |
| Dobritsa AA et al. | LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. | 2010 | Plant Physiol. | pmid:20442277 |
| RodrÃguez E et al. | Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. | 2010 | Int. J. Biol. Sci. | pmid:20440403 |
| Marreddy RK et al. | Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. | 2010 | PLoS ONE | pmid:20436673 |
| pmid:20429523 | ||||
| Rey B et al. | Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. | 2010 | BMC Physiol. | pmid:20426850 |
| pmid:20415500 | ||||
| Miller MC et al. | Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis. | 2010 | Microbiology (Reading, Engl.) | pmid:20413552 |
| pmid:20411968 | ||||
| Xu Q et al. | Discovery and comparative profiling of microRNAs in a sweet orange red-flesh mutant and its wild type. | 2010 | BMC Genomics | pmid:20398412 |
| Lukyanova LD et al. | Energotropic effect of succinate-containing derivatives of 3-hydroxypyridine. | 2009 | Bull. Exp. Biol. Med. | pmid:20396747 |
| pmid:20394417 | ||||
| Hara Y et al. | Molecular design and functional control of novel self-oscillating polymers. | 2010 | Int J Mol Sci | pmid:20386662 |
| Alcorn T and Juers DH | Progress in rational methods of cryoprotection in macromolecular crystallography. | 2010 | Acta Crystallogr. D Biol. Crystallogr. | pmid:20382989 |
| pmid:20380447 | ||||
| pmid:20380411 | ||||
| Rhee EP et al. | Metabolite profiling identifies markers of uremia. | 2010 | J. Am. Soc. Nephrol. | pmid:20378825 |
| Shimshek DR et al. | The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy. | 2010 | PLoS ONE | pmid:20368804 |
| Yuan X et al. | Disordered plane waves in the transition between target and antitarget patterns. | 2009 | Phys Rev E Stat Nonlin Soft Matter Phys | pmid:20365248 |
| Pope FD et al. | Studies of single aerosol particles containing malonic acid, glutaric acid, and their mixtures with sodium chloride. I. Hygroscopic growth. | 2010 | J Phys Chem A | pmid:20361768 |
| Kumar P et al. | Huntington's disease: pathogenesis to animal models. | 2010 Jan-Feb | Pharmacol Rep | pmid:20360611 |
| Jha SS et al. | Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages. | 2010 | BMC Microbiol. | pmid:20359357 |
| pmid:20358995 | ||||
| pmid:20355711 | ||||
| Seifert EL et al. | Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. | 2010 | PLoS ONE | pmid:20352092 |
| RANDLES CI and BIRKELAND JM | The effects of malic and malonic acids on methylene blue reduction by bacteria. | 1947 | J. Bacteriol. | pmid:20344612 |
| pmid:20333341 | ||||
| Dolezal P et al. | The essentials of protein import in the degenerate mitochondrion of Entamoeba histolytica. | 2010 | PLoS Pathog. | pmid:20333239 |
| pmid:20329785 | ||||
| Kissen R et al. | Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. | 2010 | BMC Genomics | pmid:20307264 |
| Xu H et al. | Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: effects of antipsychotics. | 2010 | Front Behav Neurosci | pmid:20305752 |
| Yaya AR et al. | Synthesis of 17 alpha-substituted ethynylestradiols: potential ligands for drug vectors. | 2010 | Steroids | pmid:20302883 |
| Gupta M et al. | Hydroxyapatite supported caesium carbonate as a new recyclable solid base catalyst for the Knoevenagel condensation in water. | 2009 | Beilstein J Org Chem | pmid:20300501 |
| FORSSMAN S and LINDSTEN T | A contribution to the pharmacodynamics of malonic, succinic, citric, aconitic, alpha-ketoglutaric and glutamic acid. | 1946 | Acta Pharmacol Toxicol (Copenh) | pmid:20295477 |
| GALAT A | Ethyl formylaminomalonate; an intermediate in the synthesis of amino acids. | 1947 | J. Am. Chem. Soc. | pmid:20292485 |
| Davydov VV | [Metabolism of free malonic acid in rat tissues]. | 1991 Jan-Feb | Ukr. Biokhim. Zh. | pmid:2028517 |
| SCHOFIELD K and SIMPSON JC | The preparation of quinoline derivatives from aromatic amines and ethyl ethoxymethylenemalonate. | 1946 | J Chem Soc | pmid:20282482 |
| pmid:20235502 | ||||
| pmid:20225879 | ||||
| Ruhaak LR et al. | Glycan labeling strategies and their use in identification and quantification. | 2010 | Anal Bioanal Chem | pmid:20225063 |
| Calkins MJ et al. | Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition. | 2010 | Toxicol. Sci. | pmid:20211941 |
| pmid:20210392 | ||||
| pmid:20210347 | ||||
| Kalonia H et al. | Targeting oxidative stress attenuates malonic acid induced Huntington like behavioral and mitochondrial alterations in rats. | 2010 | Eur. J. Pharmacol. | pmid:20188726 |
| Higa A et al. | Iron deficiency induces changes in riboflavin secretion and the mitochondrial electron transport chain in hairy roots of Hyoscyamus albus. | 2010 | J. Plant Physiol. | pmid:20181408 |
| Gonzalvez F et al. | Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin. | 2010 | PLoS ONE | pmid:20179769 |
| pmid:20178364 | ||||
| Xue ZY et al. | exo-Selective asymmetric 1,3-dipolar cycloaddition of azomethine ylides with alkylidene malonates catalyzed by AgOAc/TF-BiphamPhos. | 2010 | Chem. Commun. (Camb.) | pmid:20177630 |
| Raymond F et al. | Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue. | 2010 | BMC Genomics | pmid:20175888 |
| Zhao JS et al. | Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation. | 2010 | PLoS ONE | pmid:20174598 |
| pmid:20163152 | ||||
| Wu TY et al. | Synthesis and characterization of organic dyes containing various donors and acceptors. | 2010 | Int J Mol Sci | pmid:20162019 |
| Maeda S et al. | Active polymer gel actuators. | 2010 | Int J Mol Sci | pmid:20162001 |
| Gobert GN et al. | Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. | 2010 | PLoS Negl Trop Dis | pmid:20161728 |
| Sasaki T et al. | Closing plant stomata requires a homolog of an aluminum-activated malate transporter. | 2010 | Plant Cell Physiol. | pmid:20154005 |
| Bhattacharyya A and Pakrashi A | Requirement of an extracellular energy substrate for the guinea pig sperm acrosome reaction induced by calcium ionophore. | 1991 | Mol. Reprod. Dev. | pmid:2015088 |
| Trost BM et al. | A concise enantioselective synthesis of (-)-ranirestat. | 2010 | Org. Lett. | pmid:20148531 |
| Tonouchi A | Isolation and characterization of a novel facultative anaerobic filamentous fungus from Japanese rice field soil. | 2009 | Int J Microbiol | pmid:20148171 |
| pmid:20138130 | ||||
| Fortney K et al. | Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging. | 2010 | Genome Biol. | pmid:20128910 |
| Hinkle PC et al. | Mechanistic stoichiometry of mitochondrial oxidative phosphorylation. | 1991 | Biochemistry | pmid:2012815 |