Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Barros-Miñones L et al. | Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate. | 2013 | Biochim. Biophys. Acta | pmid:23415811 |
Yuan HN et al. | Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: synthesis of β-amino esters and anti-HIV drug DPC 083. | 2013 | Chemistry | pmid:24150893 |
Sundermann U et al. | Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. | 2013 | ACS Chem. Biol. | pmid:23181268 |
Barros-Miñones L et al. | Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate. | 2013 | Br. J. Pharmacol. | pmid:23186227 |
Salem AA et al. | Application of quantitative nuclear magnetic resonance spectroscopy for the determination ofamantadine and acyclovir in plasma and pharmaceutical samples. | 2012 Nov-Dec | J AOAC Int | pmid:23451380 |
Mahendradas P et al. | Unilateral conjunctival ulcer due to Stenotrophomonas maltophilia infection. | 2012 Mar-Apr | Indian J Ophthalmol | pmid:22446910 |
Yokoi T et al. | Formation of octacalcium phosphates with co-incorporated succinate and suberate ions. | 2012 | Dalton Trans | pmid:22249371 |
Scalliet G et al. | Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. | 2012 | PLoS ONE | pmid:22536383 |
Laurido C et al. | Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model. | 2012 | ScientificWorldJournal | pmid:22536130 |
Peng Y et al. | Poly[[μ(2)-1,3-bis-(imidazol-1-ylmeth-yl)benzene][μ(2)-2,2'-dihy-droxy-1,1'-methyl-enebis(naphthalene-3-carboxyl-ato)]zinc]. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22346812 |