Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Minato Y et al. | Malonate inhibits virulence gene expression in Vibrio cholerae. | 2013 | PLoS ONE | pmid:23675480 |
Zhang X et al. | Atomic force microscopy study of the effects of water-soluble fullerenes on the elasticity of living plant cells. | 2013 | Chem Asian J | pmid:23929723 |
Valdeolivas S et al. | The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. | 2013 | Cell Death Dis | pmid:24136226 |
Yuan HN et al. | Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: synthesis of β-amino esters and anti-HIV drug DPC 083. | 2013 | Chemistry | pmid:24150893 |
Salem AA et al. | Application of quantitative nuclear magnetic resonance spectroscopy for the determination ofamantadine and acyclovir in plasma and pharmaceutical samples. | 2012 Nov-Dec | J AOAC Int | pmid:23451380 |
Mahendradas P et al. | Unilateral conjunctival ulcer due to Stenotrophomonas maltophilia infection. | 2012 Mar-Apr | Indian J Ophthalmol | pmid:22446910 |
Liu Q et al. | Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells. | 2012 | Small | pmid:22508680 |
Liew CW et al. | Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis. | 2012 | J. Biol. Chem. | pmid:22589546 |
Ashrafian H et al. | Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. | 2012 | Cell Metab. | pmid:22405071 |
Merewitz EB et al. | Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. | 2012 | J. Exp. Bot. | pmid:22131157 |