Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:14904052 | ||||
LEE JS and LIFSON N | Studies on the conversion of acetate, lactate, and malonate to succinate in the intact rat. | 1951 | J. Biol. Chem. | pmid:14907712 |
pmid:14924659 | ||||
Hopwood DA | Cracking the polyketide code. | 2004 | PLoS Biol. | pmid:14966534 |
Murphy RC and Messer A | A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease. | 2004 | Brain Res. Mol. Brain Res. | pmid:14969746 |
pmid:14973627 | ||||
Cawthon D et al. | Investigation of proton conductance in liver mitochondria of broilers with pulmonary hypertension syndrome. | 2004 | Poult. Sci. | pmid:14979578 |
pmid:14982455 | ||||
Kiss C et al. | Cortical spreading depression augments kynurenate levels and reduces malonate toxicity in the rat cortex. | 2004 | Brain Res. | pmid:14988042 |
Taniguchi Y et al. | Differentiation of dicarboxylate transporters in mesophyll and bundle sheath chloroplasts of maize. | 2004 | Plant Cell Physiol. | pmid:14988489 |
Jeong J et al. | A nodule-specific dicarboxylate transporter from alder is a member of the peptide transporter family. | 2004 | Plant Physiol. | pmid:15001700 |
pmid:15004362 | ||||
Klivenyi P et al. | Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. | 2004 | J. Neurochem. | pmid:15009635 |
pmid:15022215 | ||||
pmid:15037207 | ||||
Ekaratanawong S et al. | Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. | 2004 | J. Pharmacol. Sci. | pmid:15037815 |
Kucera LS et al. | Synthesis and evaluation of a novel synthetic phosphocholine lipid-AZT conjugate that double-targets wild-type and drug resistant variants of HIV. | 2004 | Nucleosides Nucleotides Nucleic Acids | pmid:15043162 |
Asanuma T et al. | Protection against malonate-induced ischemic brain injury in rat by a cell-permeable peptidic c-Jun N-terminal kinase inhibitor, (L)-HIV-TAT48-57-PP-JBD20, observed by the apparent diffusion coefficient mapping magnetic resonance imaging method. | 2004 | Neurosci. Lett. | pmid:15050711 |
pmid:15051173 | ||||
pmid:15063527 | ||||
Zhang YQ and Keller NP | Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans. | 2004 | Mol. Microbiol. | pmid:15066039 |
pmid:15069502 | ||||
pmid:15074940 | ||||
Baud S et al. | gurke and pasticcino3 mutants affected in embryo development are impaired in acetyl-CoA carboxylase. | 2004 | EMBO Rep. | pmid:15088065 |
Maragos WF et al. | Striatal damage and oxidative stress induced by the mitochondrial toxin malonate are reduced in clorgyline-treated rats and MAO-A deficient mice. | 2004 | Neurochem. Res. | pmid:15098936 |
pmid:15120273 | ||||
pmid:15120856 | ||||
pmid:15124099 | ||||
pmid:15130601 | ||||
pmid:15135911 | ||||
Fleming I and Ramarao C | Decarboxylative elimination of enol triflates as a general synthesis of acetylenes. | 2004 | Org. Biomol. Chem. | pmid:15136807 |
Wu Q et al. | LC/UV/ESI-MS analysis of isoflavones in Edamame and Tofu soybeans. | 2004 | J. Agric. Food Chem. | pmid:15137811 |
pmid:15144199 | ||||
Perez J and Jeffries TW | Roles of manganese and organic acid chelators in regulating lignin degradation and biosynthesis of peroxidases by Phanerochaete chrysosporium. | 1992 | Appl. Environ. Microbiol. | pmid:1514788 |
pmid:15157075 | ||||
pmid:15157076 | ||||
Fleck J et al. | Intrastriatal malonate administration induces convulsive behaviour in rats. | 2004 | J. Inherit. Metab. Dis. | pmid:15159652 |
Liu SY et al. | Calix[4]arenes containing thiourea and amide moieties: neutral receptors towards alpha,omega-dicarboxylate anions. | 2004 | Org. Biomol. Chem. | pmid:15162208 |
Dickschat JS et al. | Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. | 2004 | Chembiochem | pmid:15174160 |
pmid:15180406 | ||||
pmid:15185315 | ||||
Zalups RK et al. | Human organic anion transporter 1 mediates cellular uptake of cysteine-S conjugates of inorganic mercury. | 2004 | Kidney Int. | pmid:15200431 |
Kanki R et al. | Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons. | 2004 | Brain Res. | pmid:15223368 |
Wang H and Shooter D | Low molecular weight dicarboxylic acids in PM10 in a city with intensive solid fuel burning. | 2004 | Chemosphere | pmid:15251287 |
pmid:15252513 | ||||
pmid:15258953 | ||||
Gołembiowska K and Dziubina A | Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats. | 2004 | Neuropharmacology | pmid:15275831 |
Solano-Serena F et al. | Degradation of isooctane by Mycobacterium austroafricanum IFP 2173: growth and catabolic pathway. | 2004 | J. Appl. Microbiol. | pmid:15281945 |
Zalups RK and Ahmad S | Homocysteine and the renal epithelial transport and toxicity of inorganic mercury: role of basolateral transporter organic anion transporter 1. | 2004 | J. Am. Soc. Nephrol. | pmid:15284288 |
pmid:15287799 |