Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Meldrum A et al. | Role of corticostriatal and nigrostriatal inputs in malonate-induced striatal toxicity. | 2001 | Neuroreport | pmid:11201098 |
Ruiz-Pérez C et al. | Magnetic coupling through the carbon skeleton of malonate in two polymorphs of ([Cu(bpy)(H2O)][Cu(bpy)(mal)(H2O)])(ClO4)2 (H2mal = malonic acid; bpy = 2,2'-bipyridine). | 2000 | Inorg Chem | pmid:11196779 |
Mossakowski MJ et al. | Effect of sodium glutamate on the morphology and histochemistry of experimental gliopathy induced in vitro by ammonia and sodium malonate. | 1975 Jan-Mar | Neuropatol Pol | pmid:1118055 |
Piasecka M et al. | Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. | 2001 | Andrologia | pmid:11167513 |
Van Westerlaak MG et al. | Chronic mitochondrial inhibition induces glutamate-mediated corticomotoneuron death in an organotypic culture model. | 2001 | Exp. Neurol. | pmid:11161628 |
Andreassen OA et al. | Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. | 2001 | Exp. Neurol. | pmid:11161607 |
Dobosz M et al. | Synthesis of new derivatives of 3-benzyl-4-R-delta 2-1,2,4-triazolin-5-one and 3,3'-methylidyne bis(4-R-1,2,4-delta 2-triazolin-5-one). | 2000 May-Jun | Acta Pol Pharm | pmid:11143710 |
pmid:11141054 | ||||
Kamo T et al. | Changes in the content and biosynthesis of phytoalexins in banana fruit. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11129580 |
Ramaseshan M et al. | Solid phase combinatorial synthesis of a library of macro-heterocycles and related acyclic compounds. | 2000 Nov-Dec | J Comb Chem | pmid:11126291 |
Ling F et al. | A role for MHR1, a gene required for mitochondrial genetic recombination, in the repair of damage spontaneously introduced in yeast mtDNA. | 2000 | Nucleic Acids Res. | pmid:11121487 |
Lee HY et al. | Identification and characterization of a novel transcriptional regulator, MatR, for malonate metabolism in Rhizobium leguminosarum bv. trifolii. | 2000 | Eur. J. Biochem. | pmid:11106435 |
Ward OP and Singh A | Enzymatic asymmetric synthesis by decarboxylases. | 2000 | Curr. Opin. Biotechnol. | pmid:11102784 |
Tóth V and Emódy L | Proteus virulence: involvement of the pore forming alpha-hemolysin (a short review). | 2000 | Acta Microbiol Immunol Hung | pmid:11056765 |
Koo JH et al. | The malonate decarboxylase operon of Acinetobacter calcoaceticus KCCM 40902 is regulated by malonate and the transcriptional repressor MdcY. | 2000 | J. Bacteriol. | pmid:11053382 |
Hoenke S et al. | Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. | 2000 | Biochemistry | pmid:11052675 |
Meldrum A et al. | Age-dependence of malonate-induced striatal toxicity. | 2000 | Exp Brain Res | pmid:11045358 |
Ouyang Q et al. | Transition from spirals to defect-mediated turbulence driven by a doppler instability. | 2000 | Phys. Rev. Lett. | pmid:11017437 |
Chaimbault C et al. | Physicochemical and crystallographic evidence for polymorphism of the racemic ethyl (2-chloromethyl-2,3-dihydro-5H-oxazolo [3, 2-a]pyrimidin-5-one)-6-carboxylate. | 2000 | J Pharm Sci | pmid:11015694 |
Knobling A et al. | Malonyl and palmityl transferase-less mutants of the yeast fatty-acid-synthetase complex. | 1975 | Eur. J. Biochem. | pmid:1100391 |