Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:12862486 | ||||
Wang SC et al. | Reactions of trans-3-chloroacrylic acid dehalogenase with acetylene substrates: consequences of and evidence for a hydration reaction. | 2003 | Biochemistry | pmid:12873137 |
pmid:12876372 | ||||
pmid:12880697 | ||||
Renné P et al. | The Arabidopsis mutant dct is deficient in the plastidic glutamate/malate translocator DiT2. | 2003 | Plant J. | pmid:12887583 |
Newell DR et al. | Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK. | 2003 | Br. J. Cancer | pmid:12888809 |
pmid:12895096 | ||||
pmid:12898627 | ||||
pmid:12904032 | ||||
Shefer TV et al. | Effect of sodium succinate on gas exchange in rats with barbiturate-induced coma. | 2003 | Bull. Exp. Biol. Med. | pmid:12910308 |
Furin A et al. | Synthesis, characterization and preliminary cytotoxicity assays of poly(ethylene glycol)-malonato-Pt-DACH conjugates. | 2003 Jul-Aug | Eur J Med Chem | pmid:12932905 |
pmid:12950184 | ||||
Ehrhart J and Zeevalk GD | Cooperative interaction between ascorbate and glutathione during mitochondrial impairment in mesencephalic cultures. | 2003 | J. Neurochem. | pmid:12950457 |
pmid:12971763 | ||||
pmid:12971787 | ||||
Kölker S et al. | Methylmalonic acid, a biochemical hallmark of methylmalonic acidurias but no inhibitor of mitochondrial respiratory chain. | 2003 | J. Biol. Chem. | pmid:12972416 |
BUSCH H and POTTER VR | Studies on tissue metabolism by means of in vivo metabolic blocking technics. I. A survey of changes induced by malonate in tissues of tumor-bearing rats. | 1952 | Cancer Res. | pmid:12978997 |
pmid:12999621 | ||||
pmid:12999622 | ||||
BUSCH H and POTTER VR | Succinate accumulation in vivo following injection of malonate. | 1952 | J. Biol. Chem. | pmid:12999717 |