Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Miki T | [Inhibitors of complex I and II of the mitochondrial respiratory chain]. | 2002 | Nippon Rinsho | pmid:12013844 |
pmid:12020876 | ||||
Nørbaek R et al. | Anthocyanins from flowers of Cichorium intybus. | 2002 | Phytochemistry | pmid:12031425 |
Saito N et al. | Acylated anthocyanins from the blue-violet flowers of Anemone coronaria. | 2002 | Phytochemistry | pmid:12031427 |
Shin S et al. | Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature. | 2002 | EMBO J. | pmid:12032064 |
DoganKoruznjak J et al. | Synthesis, photochemical synthesis and antitumor evaluation of novel derivatives of thieno[3',2':4,5]thieno[2,3-c]quinolones. | 2002 | Chem. Pharm. Bull. | pmid:12036023 |
Uenishi J and Hamada M | Stereospecific substitution of enantiomerically pure 1-(2-pyridinyl)ethyl methanesulfonate with beta-dicarbony compounds. | 2002 | Chem. Pharm. Bull. | pmid:12036035 |
pmid:12049975 | ||||
pmid:12051770 | ||||
pmid:12054936 | ||||
Ogier de Baulny H and Saudubray JM | Branched-chain organic acidurias. | 2002 | Semin Neonatol | pmid:12069539 |
Zeevalk GD et al. | Protection of malonate-induced GABA but not dopamine loss by GABA transporter blockade in rat striatum. | 2002 | Exp. Neurol. | pmid:12093096 |
Dedeoglu A et al. | Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid. | 2002 | Exp. Neurol. | pmid:12093104 |
Hassel B et al. | Cerebral dicarboxylate transport and metabolism studied with isotopically labelled fumarate, malate and malonate. | 2002 | J. Neurochem. | pmid:12124442 |
Pain F et al. | In vivo quantification of localized neuronal activation and inhibition in the rat brain using a dedicated high temporal-resolution beta +-sensitive microprobe. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12136134 |
Liang X et al. | Structure and dynamics of metallomacrocycles: recognition of zinc xylyl-bicyclam by an HIV coreceptor. | 2002 | J. Am. Chem. Soc. | pmid:12149014 |
Saraswathi NT and Vijayan M | X-ray studies on crystalline complexes involving amino acids and peptides. XXXIX. Crystal structures of malonic acid complexes of DL- and L-histidine. Preservation of aggregation pattern on reversal of chirality. | 2002 | Acta Crystallogr., B | pmid:12149565 |
pmid:12154133 | ||||
Rancan F et al. | Cytotoxicity and photocytotoxicity of a dendritic C(60) mono-adduct and a malonic acid C(60) tris-adduct on Jurkat cells. | 2002 | J. Photochem. Photobiol. B, Biol. | pmid:12167314 |
pmid:12182598 |