Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nam KH et al. | Insight into the antibacterial drug design and architectural mechanism of peptide recognition from the E. faecium peptide deformylase structure. | 2009 | Proteins | pmid:18831047 |
| Maertens B et al. | Gene optimization mechanisms: a multi-gene study reveals a high success rate of full-length human proteins expressed in Escherichia coli. | 2010 | Protein Sci. | pmid:20506237 |
| McPherson A | A comparison of salts for the crystallization of macromolecules. | 2001 | Protein Sci. | pmid:11266627 |
| Jung JW et al. | The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies. | 2000 | Protein Sci. | pmid:10933494 |
| Scheer JM et al. | Malonate-assisted purification of human caspases. | 2005 | Protein Expr. Purif. | pmid:15802232 |
| Li J et al. | Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6. | 2013 | Protein Cell | pmid:23807634 |
| LIFSON N and STOLEN JA | Metabolism of C13-carboxyl-labeled malonate by the intact mouse. | 1950 | Proc. Soc. Exp. Biol. Med. | pmid:15440851 |
| Risquez A et al. | Effects of malonate administration on renal ammoniagenesis in intact dogs. | 1989 | Proc. Soc. Exp. Biol. Med. | pmid:2602392 |
| POTTER VR and SIMONSON H | Sequential blocking of metabolic pathways in vivo. | 1951 | Proc. Soc. Exp. Biol. Med. | pmid:14816386 |
| Calkins MJ et al. | Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15611470 |