Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Salinero KK et al. | Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation. | 2009 | BMC Genomics | pmid:19650930 |
| Kim MI et al. | In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents. | 2009 | Org. Lett. | pmid:19653678 |
| Yang L et al. | Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins. | 2009 | Neurobiol. Dis. | pmid:19660549 |
| pmid:19666236 | ||||
| Borutaite V et al. | Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release. | 2009 | J. Biomed. Sci. | pmid:19671187 |
| Yesilirmak F and Sayers Z | Heterelogous expression of plant genes. | 2009 | Int J Plant Genomics | pmid:19672459 |
| Burow LC et al. | Induction of membrane permeability in Escherichia coli mediated by lysis protein of the ColE7 operon. | 2009 | FEMS Microbiol. Lett. | pmid:19673051 |
| Zhao L et al. | Synergetic effect of ultrasound with dual fields for the degradation of nitrobenzene in aqueous solution. | 2009 | Environ. Sci. Technol. | pmid:19673312 |
| Ohta Y et al. | Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization. | 2009 | J. Org. Chem. | pmid:19673483 |
| Emamzadah S et al. | Cyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffraction. | 2009 | Acta Crystallogr. D Biol. Crystallogr. | pmid:19690369 |
| Yang HB et al. | Facile self-assembly of neutral dendritic metallocycles via oxygen-to-platinum coordination. | 2009 | J. Org. Chem. | pmid:19691266 |
| pmid:19695309 | ||||
| de Groot MJ et al. | Metabolite and reaction inference based on enzyme specificities. | 2009 | Bioinformatics | pmid:19696044 |
| Shoukry EM | Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents. | 2009 | Bioinorg Chem Appl | pmid:19696935 |
| Vyas P and Gulati A | Organic acid production in vitro and plant growth promotion in maize under controlled environment by phosphate-solubilizing fluorescent Pseudomonas. | 2009 | BMC Microbiol. | pmid:19698133 |
| Miyata N et al. | Enzymatic formation of manganese oxides by an Acremonium-like hyphomycete fungus, strain KR21-2. | 2004 | FEMS Microbiol. Ecol. | pmid:19712351 |
| Klimov AN et al. | [Does malonate take part in the synthesis of sterols?]. | 1990 | Biokhimiia | pmid:1972338 |
| pmid:19727504 | ||||
| pmid:19734282 | ||||
| Okrasa K et al. | Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19739187 |
| Choudhury SR et al. | Robust recognition of malonate and 2-amino-4-picolinium in conjunction with M(II) as a triad (M = Ni/Co/Mn): role of this highly stable hydrogen-bonded motif in driving supramolecular self-assembly. | 2009 | Dalton Trans | pmid:19759933 |
| pmid:19761198 | ||||
| Luévano-MartÃnez LA et al. | Identification of the mitochondrial carrier that provides Yarrowia lipolytica with a fatty acid-induced and nucleotide-sensitive uncoupling protein-like activity. | 2010 | Biochim. Biophys. Acta | pmid:19766093 |
| pmid:19772479 | ||||
| Ndinguri MW et al. | Peptide targeting of platinum anti-cancer drugs. | 2009 | Bioconjug. Chem. | pmid:19775102 |
| Foret J et al. | Synthesis and evaluation of non-hydrolyzable D-mannose 6-phosphate surrogates reveal 6-deoxy-6-dicarboxymethyl-D-mannose as a new strong inhibitor of phosphomannose isomerases. | 2009 | Bioorg. Med. Chem. | pmid:19783448 |
| Bringmann G et al. | Convergence in the biosynthesis of acetogenic natural products from plants, fungi, and bacteria. | Phytochemistry | pmid:19786287 | |
| Hoffman HE et al. | Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. | 2009 | J. Med. Chem. | pmid:19791805 |
| Rintala E et al. | Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. | 2009 | BMC Genomics | pmid:19804647 |
| pmid:19805876 | ||||
| Niimi M et al. | Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. | 2009 | J. Biomed. Sci. | pmid:19825180 |
| Goldstein P et al. | Clustering of protein domains for functional and evolutionary studies. | 2009 | BMC Bioinformatics | pmid:19832975 |
| pmid:19834936 | ||||
| pmid:19838755 | ||||
| Strickler MA et al. | Functional characterization of a Na(+)-coupled dicarboxylate transporter from Bacillus licheniformis. | 2009 | Biochim. Biophys. Acta | pmid:19840771 |
| Kozjak-Pavlovic V et al. | Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis. | 2009 | PLoS Pathog. | pmid:19851451 |
| Liu B et al. | Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation. | 2010 | Mol. Cell. Biochem. | pmid:19851835 |
| Baldwin A et al. | Multilocus sequence typing of Cronobacter sakazakii and Cronobacter malonaticus reveals stable clonal structures with clinical significance which do not correlate with biotypes. | 2009 | BMC Microbiol. | pmid:19852808 |
| pmid:19857862 | ||||
| Perrot O et al. | Quantitative assessment of stereotyped and challenged locomotion after lesion of the striatum: a 3D kinematic study in rats. | 2009 | PLoS ONE | pmid:19859550 |
| Tsubogo T et al. | Chiral calcium catalysts with neutral coordinative ligands: enantioselective 1,4-addition reactions of 1,3-dicarbonyl compounds to nitroalkenes. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19862785 |
| Ramel C et al. | Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate. | 2009 | BMC Biochem. | pmid:19863801 |
| pmid:19865168 | ||||
| Xu XM et al. | Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. | 2009 | PLoS ONE | pmid:19865480 |
| Bar NS and Radde N | Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model. | 2009 | BMC Syst Biol | pmid:19903354 |
| pmid:19907771 | ||||
| Bunik VI et al. | Effect of alpha-ketoglutarate and its structural analogues on hysteretic properties of alpha-ketoglutarate dehydrogenase. | 1991 | FEBS Lett. | pmid:1991504 |
| Pin C et al. | Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase. | 2009 | BMC Syst Biol | pmid:19917103 |
| pmid:19921052 | ||||
| pmid:19921898 | ||||
| Kagan ML et al. | Geometric phase shifts in chemical oscillators. | 1991 | Nature | pmid:1992353 |
| Spinks D et al. | Investigation of trypanothione reductase as a drug target in Trypanosoma brucei. | 2009 | ChemMedChem | pmid:19924760 |
| Tan Y et al. | Effects of precursor concentration and acidic sulfate in aqueous glyoxal-OH radical oxidation and implications for secondary organic aerosol. | 2009 | Environ. Sci. Technol. | pmid:19924930 |
| Senoglu M et al. | Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve. | 2009 | J Brachial Plex Peripher Nerve Inj | pmid:19939272 |
| pmid:19943692 | ||||
| Azuma Y and Ota M | An evaluation of minimal cellular functions to sustain a bacterial cell. | 2009 | BMC Syst Biol | pmid:19943949 |
| pmid:19957319 | ||||
| Stevens P and van Elsas JD | Genetic and phenotypic diversity of Ralstonia solanacearum biovar 2 strains obtained from Dutch waterways. | 2010 | Antonie Van Leeuwenhoek | pmid:19960250 |
| Spindler M et al. | Coenzyme Q10 effects in neurodegenerative disease. | 2009 | Neuropsychiatr Dis Treat | pmid:19966907 |
| Vieira N et al. | Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans. | 2010 | Mol. Microbiol. | pmid:19968788 |
| Wang Z et al. | Photochemical cycling of iron mediated by dicarboxylates: special effect of malonate. | 2010 | Environ. Sci. Technol. | pmid:20000366 |
| Gebhard S et al. | The low-affinity phosphate transporter PitA is dispensable for in vitro growth of Mycobacterium smegmatis. | 2009 | BMC Microbiol. | pmid:20003273 |
| Hamilton S et al. | The transcriptional programme of Salmonella enterica serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms. | 2009 | BMC Genomics | pmid:20003355 |
| Qureshi IA et al. | Crystallographic structure of ubiquitin in complex with cadmium ions. | 2009 | BMC Res Notes | pmid:20003470 |
| Partha R and Conyers JL | Biomedical applications of functionalized fullerene-based nanomaterials. | 2009 | Int J Nanomedicine | pmid:20011243 |
| Pieretti I et al. | The complete genome sequence of Xanthomonas albilineans provides new insights into the reductive genome evolution of the xylem-limited Xanthomonadaceae. | 2009 | BMC Genomics | pmid:20017926 |
| Benedito VA et al. | Genomic inventory and transcriptional analysis of Medicago truncatula transporters. | 2010 | Plant Physiol. | pmid:20023147 |
| Arambula JF et al. | Gadolinium texaphyrin (Gd-Tex)-malonato-platinum conjugates: synthesis and comparison with carboplatin in normal and Pt-resistant cell lines. | 2009 | Dalton Trans | pmid:20023913 |
| Cowen D et al. | A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20034791 |
| Duez S et al. | Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues. | 2010 | Bioorg. Med. Chem. | pmid:20036564 |
| Bazil JN et al. | Modeling mitochondrial bioenergetics with integrated volume dynamics. | 2010 | PLoS Comput. Biol. | pmid:20052270 |
| Moore PK and Horsthemke W | Three-dimensional patterns in the Lengyel-Rabai-Epstein model of the chlorine dioxide-iodine-malonic acid reaction. | 2009 | Chaos | pmid:20059212 |
| Wang YH et al. | Diastereoselective gamma-vinyl butyrolactone synthesis via gold catalyzed cyclization of allylic acetate. | 2010 | Chem. Commun. (Camb.) | pmid:20062867 |
| Varela C et al. | New structural and functional defects in polyphosphate deficient bacteria: a cellular and proteomic study. | 2010 | BMC Microbiol. | pmid:20067623 |
| Demetrius LA et al. | Cancer proliferation and therapy: the Warburg effect and quantum metabolism. | 2010 | Theor Biol Med Model | pmid:20085650 |
| Licht TR et al. | Effects of apples and specific apple components on the cecal environment of conventional rats: role of apple pectin. | 2010 | BMC Microbiol. | pmid:20089145 |
| Ichida K | What lies behind serum urate concentration? Insights from genetic and genomic studies. | 2009 | Genome Med | pmid:20090896 |
| Wang YQ et al. | Diverse manganese(II) coordination polymers with mixed azide and zwitterionic dicarboxylate ligands: structure and magnetic properties. | 2010 | Inorg Chem | pmid:20095647 |
| Kobayashi S et al. | Chiral zirconium complex as Brønsted base catalyst in asymmetric direct-type Mannich reactions. | 2010 | Chem Asian J | pmid:20099294 |
| Pisarenko AN et al. | Rapid analysis of perchlorate, chlorate and bromate ions in concentrated sodium hypochlorite solutions. | 2010 | Anal. Chim. Acta | pmid:20103127 |
| Smith MA et al. | The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. | 2010 | J. Biol. Chem. | pmid:20106978 |
| Goncalves S et al. | Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples. | 2010 | BMC Biochem. | pmid:20109171 |
| Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
| Hahn MW et al. | Limnohabitans australis sp. nov., isolated from a freshwater pond, and emended description of the genus Limnohabitans. | 2010 | Int. J. Syst. Evol. Microbiol. | pmid:20118294 |
| Furrow SD and Aurentz DJ | Reactions of iodomalonic acid, diiodomalonic acid, and other organics in the Briggs-Rauscher oscillating system. | 2010 | J Phys Chem A | pmid:20121222 |
| pmid:20123102 | ||||
| Hinkle PC et al. | Mechanistic stoichiometry of mitochondrial oxidative phosphorylation. | 1991 | Biochemistry | pmid:2012815 |
| Fortney K et al. | Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging. | 2010 | Genome Biol. | pmid:20128910 |
| pmid:20138130 | ||||
| Tonouchi A | Isolation and characterization of a novel facultative anaerobic filamentous fungus from Japanese rice field soil. | 2009 | Int J Microbiol | pmid:20148171 |
| Trost BM et al. | A concise enantioselective synthesis of (-)-ranirestat. | 2010 | Org. Lett. | pmid:20148531 |
| Bhattacharyya A and Pakrashi A | Requirement of an extracellular energy substrate for the guinea pig sperm acrosome reaction induced by calcium ionophore. | 1991 | Mol. Reprod. Dev. | pmid:2015088 |
| Sasaki T et al. | Closing plant stomata requires a homolog of an aluminum-activated malate transporter. | 2010 | Plant Cell Physiol. | pmid:20154005 |
| Gobert GN et al. | Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. | 2010 | PLoS Negl Trop Dis | pmid:20161728 |
| Maeda S et al. | Active polymer gel actuators. | 2010 | Int J Mol Sci | pmid:20162001 |
| Wu TY et al. | Synthesis and characterization of organic dyes containing various donors and acceptors. | 2010 | Int J Mol Sci | pmid:20162019 |
| pmid:20163152 | ||||
| Zhao JS et al. | Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation. | 2010 | PLoS ONE | pmid:20174598 |
| Raymond F et al. | Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue. | 2010 | BMC Genomics | pmid:20175888 |
| Xue ZY et al. | exo-Selective asymmetric 1,3-dipolar cycloaddition of azomethine ylides with alkylidene malonates catalyzed by AgOAc/TF-BiphamPhos. | 2010 | Chem. Commun. (Camb.) | pmid:20177630 |