Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hara Y et al. | Generative force of self-oscillating gel. | 2014 | J Phys Chem B | pmid:24524539 |
| Preska Steinberg A et al. | Target Turing patterns and growth dynamics in the chlorine dioxide-iodine-malonic acid reaction. | 2014 | J Phys Chem A | pmid:24601764 |
| Ghorai S et al. | Hygroscopic properties of internally mixed particles composed of NaCl and water-soluble organic acids. | 2014 | Environ. Sci. Technol. | pmid:24437520 |
| Wang Y et al. | Dynamic metabolites profile of cerebral ischemia/reperfusion revealed by (1)H NMR-based metabolomics contributes to potential biomarkers. | 2014 | Int J Clin Exp Pathol | pmid:25120785 |
| Gueguen C et al. | Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition. | 2014 | PLoS ONE | pmid:24586272 |
| Barros-Miñones L et al. | Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate. | 2013 | Biochim. Biophys. Acta | pmid:23415811 |
| Bew SP et al. | Malonic acid half oxyesters and thioesters: solvent-free synthesis and DFT analysis of their enols. | 2013 | Org. Lett. | pmid:23876089 |
| Chen WN and Tan KY | "Malonate uptake and metabolism in Saccharomyces cerevisiae". | 2013 | Appl. Biochem. Biotechnol. | pmid:23813405 |
| Li J et al. | Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6. | 2013 | Protein Cell | pmid:23807634 |
| Bao X et al. | A chemical probe for lysine malonylation. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23533089 |
| Kumar A et al. | Synergistical neuroprotection of rofecoxib and statins against malonic acid induced Huntington's disease like symptoms and related cognitive dysfunction in rats. | 2013 | Eur. J. Pharmacol. | pmid:23562615 |
| MacCrehan WA and White CM | Simplified ultrasonically- and microwave-assisted solvent extractions for the determination of ginsenosides in powdered Panax ginseng rhizomes using liquid chromatography with UV absorbance or electrospray mass spectrometric detection. | 2013 | Anal Bioanal Chem | pmid:23564283 |
| Darvas M et al. | Molecular dynamics simulations of the water adsorption around malonic acid aerosol models. | 2013 | Phys Chem Chem Phys | pmid:23702947 |
| Zhou S et al. | Production of 3-hydroxypropionic acid from glycerol by recombinant Pseudomonas denitrificans. | 2013 | Biotechnol. Bioeng. | pmid:23775313 |
| Minato Y et al. | Malonate inhibits virulence gene expression in Vibrio cholerae. | 2013 | PLoS ONE | pmid:23675480 |
| Zhang X et al. | Atomic force microscopy study of the effects of water-soluble fullerenes on the elasticity of living plant cells. | 2013 | Chem Asian J | pmid:23929723 |
| Valdeolivas S et al. | The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. | 2013 | Cell Death Dis | pmid:24136226 |
| Yuan HN et al. | Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: synthesis of β-amino esters and anti-HIV drug DPC 083. | 2013 | Chemistry | pmid:24150893 |
| Sundermann U et al. | Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. | 2013 | ACS Chem. Biol. | pmid:23181268 |
| Barros-Miñones L et al. | Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate. | 2013 | Br. J. Pharmacol. | pmid:23186227 |