Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Aklujkar M et al. | The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments. | 2010 | BMC Genomics | pmid:20828392 |
RodrÃguez E et al. | Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. | 2010 | Int. J. Biol. Sci. | pmid:20440403 |
Ojha B et al. | 2-Alkylmalonic acid: amphiphilic chelator and a potent inhibitor of metalloenzyme. | 2010 | J Phys Chem B | pmid:20669918 |
Pope FD et al. | Studies of single aerosol particles containing malonic acid, glutaric acid, and their mixtures with sodium chloride. II. Liquid-state vapor pressures of the acids. | 2010 | J Phys Chem A | pmid:20799753 |
Müller BA and Dhalla NS | Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart. | 2010 | Curr Cardiol Rev | pmid:22043201 |
Yaya AR et al. | Synthesis of 17 alpha-substituted ethynylestradiols: potential ligands for drug vectors. | 2010 | Steroids | pmid:20302883 |
Mao Z et al. | Water-compatible iminium activation: highly enantioselective organocatalytic Michael addition of malonates to α,β-unsaturated enones. | 2010 | J. Org. Chem. | pmid:20936828 |
Galley HF | Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis. | 2010 | Crit Care | pmid:20804578 |
Cervellati R et al. | Experimental and mechanistic investigation of an iodomalonic acid-based Briggs-Rauscher oscillator and its perturbations by resorcinol. | 2010 | J Phys Chem A | pmid:21082849 |
Wilhelm EA et al. | Anticonvulsant effect of (E)-2-benzylidene-4-phenyl-1,3-diselenole in a pilocarpine model in mice. | 2010 | Life Sci. | pmid:20888349 |
Bazil JN et al. | Modeling mitochondrial bioenergetics with integrated volume dynamics. | 2010 | PLoS Comput. Biol. | pmid:20052270 |
Taghavi S et al. | Genome sequence of the plant growth promoting endophytic bacterium Enterobacter sp. 638. | 2010 | PLoS Genet. | pmid:20485560 |
Hauser PM et al. | Comparative genomics suggests that the fungal pathogen pneumocystis is an obligate parasite scavenging amino acids from its host's lungs. | 2010 | PLoS ONE | pmid:21188143 |
RÃos G et al. | Identification of a GCC transcription factor responding to fruit colour change events in citrus through the transcriptomic analyses of two mutants. | 2010 | BMC Plant Biol. | pmid:21159189 |
Cabral JP | Water microbiology. Bacterial pathogens and water. | 2010 | Int J Environ Res Public Health | pmid:21139855 |
Li S et al. | Constructing a fish metabolic network model. | 2010 | Genome Biol. | pmid:21114829 |
Furrow SD and Aurentz DJ | Reactions of iodomalonic acid, diiodomalonic acid, and other organics in the Briggs-Rauscher oscillating system. | 2010 | J Phys Chem A | pmid:20121222 |
Kalonia H et al. | Targeting oxidative stress attenuates malonic acid induced Huntington like behavioral and mitochondrial alterations in rats. | 2010 | Eur. J. Pharmacol. | pmid:20188726 |
Lee KY et al. | The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies. | 2010 | Microb. Cell Fact. | pmid:21092328 |
Higa A et al. | Iron deficiency induces changes in riboflavin secretion and the mitochondrial electron transport chain in hairy roots of Hyoscyamus albus. | 2010 | J. Plant Physiol. | pmid:20181408 |
Binukumar BK et al. | Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes. | 2010 | Mol Brain | pmid:21073741 |
Xue ZY et al. | exo-Selective asymmetric 1,3-dipolar cycloaddition of azomethine ylides with alkylidene malonates catalyzed by AgOAc/TF-BiphamPhos. | 2010 | Chem. Commun. (Camb.) | pmid:20177630 |
Kobayashi S et al. | Chiral zirconium complex as Brønsted base catalyst in asymmetric direct-type Mannich reactions. | 2010 | Chem Asian J | pmid:20099294 |
Pisarenko AN et al. | Rapid analysis of perchlorate, chlorate and bromate ions in concentrated sodium hypochlorite solutions. | 2010 | Anal. Chim. Acta | pmid:20103127 |
Smith MA et al. | The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. | 2010 | J. Biol. Chem. | pmid:20106978 |
Cowen D et al. | A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20034791 |
Axelrod HL et al. | Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris. | 2010 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:20944231 |
Letek M et al. | The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. | 2010 | PLoS Genet. | pmid:20941392 |
Vermeulen RC et al. | Patients with chronic fatigue syndrome performed worse than controls in a controlled repeated exercise study despite a normal oxidative phosphorylation capacity. | 2010 | J Transl Med | pmid:20937116 |
Paul D et al. | Complete genome and comparative analysis of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5. | 2010 | BMC Genomics | pmid:20863402 |
Edwards TE et al. | Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. | 2010 | PLoS ONE | pmid:20862217 |
Hagopian K et al. | Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice. | 2010 | PLoS ONE | pmid:20856881 |
Gao X et al. | Engineered polyketide biosynthesis and biocatalysis in Escherichia coli. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20853106 |
Gong M et al. | The evolutionary trajectory of mitochondrial carrier family during metazoan evolution. | 2010 | BMC Evol. Biol. | pmid:20843381 |
Baek JG et al. | Metabolite profiling of Cheonggukjang, a fermented soybean paste, inoculated with various Bacillus strains during fermentation. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20834151 |
Sripadi P et al. | Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry. | 2010 | PLoS ONE | pmid:20830293 |
Nurmohamed S et al. | Molecular recognition between Escherichia coli enolase and ribonuclease E. | 2010 | Acta Crystallogr. D Biol. Crystallogr. | pmid:20823555 |
Hou Y et al. | Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages. | 2010 | Proteome Sci | pmid:20822545 |
Kajiro H et al. | Flexible two-dimensional square-grid coordination polymers: structures and functions. | 2010 | Int J Mol Sci | pmid:21152303 |
Chattopadhyay K et al. | Mechanistic origin of the stereodivergence in decarboxylative allylation. | 2010 | Org. Lett. | pmid:20533852 |
Maertens B et al. | Gene optimization mechanisms: a multi-gene study reveals a high success rate of full-length human proteins expressed in Escherichia coli. | 2010 | Protein Sci. | pmid:20506237 |
Wanders RJ et al. | The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. | 2010 | J. Inherit. Metab. Dis. | pmid:20490924 |
Kellmann R et al. | Biosynthesis and molecular genetics of polyketides in marine dinoflagellates. | 2010 | Mar Drugs | pmid:20479965 |
Chhabra S et al. | Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus. | 2010 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:20445263 |
Marreddy RK et al. | Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. | 2010 | PLoS ONE | pmid:20436673 |
Rey B et al. | Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. | 2010 | BMC Physiol. | pmid:20426850 |
Miller MC et al. | Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis. | 2010 | Microbiology (Reading, Engl.) | pmid:20413552 |
Maeda S et al. | Active polymer gel actuators. | 2010 | Int J Mol Sci | pmid:20162001 |
Gobert GN et al. | Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. | 2010 | PLoS Negl Trop Dis | pmid:20161728 |
Sasaki T et al. | Closing plant stomata requires a homolog of an aluminum-activated malate transporter. | 2010 | Plant Cell Physiol. | pmid:20154005 |
Trost BM et al. | A concise enantioselective synthesis of (-)-ranirestat. | 2010 | Org. Lett. | pmid:20148531 |
Fortney K et al. | Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging. | 2010 | Genome Biol. | pmid:20128910 |
Hahn MW et al. | Limnohabitans australis sp. nov., isolated from a freshwater pond, and emended description of the genus Limnohabitans. | 2010 | Int. J. Syst. Evol. Microbiol. | pmid:20118294 |
Goncalves S et al. | Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples. | 2010 | BMC Biochem. | pmid:20109171 |
Licht TR et al. | Effects of apples and specific apple components on the cecal environment of conventional rats: role of apple pectin. | 2010 | BMC Microbiol. | pmid:20089145 |
Varela C et al. | New structural and functional defects in polyphosphate deficient bacteria: a cellular and proteomic study. | 2010 | BMC Microbiol. | pmid:20067623 |
Yoshida R | Design of self-oscillating gels and application to biomimetic actuators. | 2010 | Sensors (Basel) | pmid:22294901 |
McKinlay JB et al. | A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. | 2010 | BMC Genomics | pmid:21118570 |
Wu J et al. | Metabolic changes reveal the development of schistosomiasis in mice. | 2010 | PLoS Negl Trop Dis | pmid:20824219 |
Liu HT et al. | Poly[[diaqua-(μ(4)-l-tartrato)(μ(2)-l-tartrato)dizinc(II)] tetra-hydrate]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21580485 |
Shi ZF et al. | Triaqua-(1,10-phenanthroline-2,9-dicarboxyl-ato)cobalt(II) dihydrate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21580484 |
Liang WX | 2-Carb-oxy-1-(3-nitro-phen-yl)ethanaminium perchlorate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579810 |
Hemamalini M and Fun HK | 2-Amino-5-chloro-pyridinium 2-carb-oxy-acetate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579558 |
Hemamalini M and Fun HK | 2-Amino-5-methyl-pyridinium 2-carb-oxy-acetate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579546 |
Dobritsa AA et al. | LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. | 2010 | Plant Physiol. | pmid:20442277 |
Liu SX et al. | Dimethyl 2-(2,4,6-trimethoxy-benz-yl)malonate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579465 |
Liu SX et al. | Dimethyl 2-(2-quinolylmeth-yl)malonate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579464 |
Shahani T et al. | Dimethyl 4-(3,4-dimethoxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579441 |
Wilseck ZM and Laduca RL | Poly[[μ(4)-bis-(4-pyridyl-carbon-yl)piperazine-κN:N':O:O']bis-(thio-cyanato-κN)cobalt(II)]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579345 |
Pochodylo AL and Laduca RL | catena-Poly[[diaqua-cadmium(II)]bis-(μ-2,2-dimethyl-butane-dioato-κO,O':O'',O''')[diaqua-cadmium(II)]-μ-1,4-bis-(3-pyridylmeth-yl)piperazine-κN:N]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579341 |
Win YF et al. | Poly[[aquadi-μ(3)-malonato-hexaphenyl-ditin(IV)] acetone solvate]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579332 |
Chen YM and Xie QF | [Malonato(2-)-κO,O']bis-(1,10-phenanthroline-κN,N')zinc(II) penta-hydrate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522585 |
Guo ML et al. | Poly[tetra-aqua-di-μ(4)-malonato-barium(II)cadmium(II)]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522548 |
Guo ML | Poly[diaqua-μ(3)-4-nitro-phthalato-copper(II)]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522547 |
Demetrius LA et al. | Cancer proliferation and therapy: the Warburg effect and quantum metabolism. | 2010 | Theor Biol Med Model | pmid:20085650 |
Scotti C et al. | Cell-cycle inhibition by Helicobacter pylori L-asparaginase. | 2010 | PLoS ONE | pmid:21085483 |
Luévano-MartÃnez LA et al. | Identification of the mitochondrial carrier that provides Yarrowia lipolytica with a fatty acid-induced and nucleotide-sensitive uncoupling protein-like activity. | 2010 | Biochim. Biophys. Acta | pmid:19766093 |
Kumar P et al. | Huntington's disease: pathogenesis to animal models. | 2010 Jan-Feb | Pharmacol Rep | pmid:20360611 |
Park SR et al. | Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering. | 2011 | J. Microbiol. Biotechnol. | pmid:22127124 |
Miller SE et al. | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. | 2011 | Cell | pmid:22118466 |
Lallous N et al. | The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers. | 2011 | PLoS ONE | pmid:22096602 |
Quarrie R et al. | Ischemic preconditioning decreases mitochondrial proton leak and reactive oxygen species production in the postischemic heart. | 2011 | J. Surg. Res. | pmid:21035133 |
Hidaka M and Yoshida R | Self-oscillating gel composed of thermosensitive polymer exhibiting higher LCST. | 2011 | J Control Release | pmid:21130818 |
Walash MI et al. | Determination of oxybutynin in pharmaceuticals via reaction with mixed acids anhydrides: application to content uniformity testing. | 2011 | J Fluoresc | pmid:21046437 |
Phan I et al. | Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. | 2011 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:21904061 |
Holder JW et al. | Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development. | 2011 | PLoS Genet. | pmid:21931557 |
Mamtimin B et al. | Plasma metabonomic analysis with ¹H nuclear magnetic resonance revealing the relationship of different tumors and the disease homology theory of traditional Uyghur medicine. | 2011 | Chin J Integr Med | pmid:21390577 |
Lillehoj HS et al. | Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens. | 2011 | BMC Proc | pmid:21645315 |
Eloe EA et al. | Going deeper: metagenome of a hadopelagic microbial community. | 2011 | PLoS ONE | pmid:21629664 |
Vajpayee V et al. | Self-assembled arene-ruthenium-based rectangles for the selective sensing of multi-carboxylate anions. | 2011 | Chemistry | pmid:21611989 |
Antkiewicz-Michaluk L et al. | Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release. | 2011 | Neurotox Res | pmid:21069490 |
Lejon S et al. | Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. | 2011 | J. Biol. Chem. | pmid:21047798 |
Odendaal AY et al. | Isomeric trimethylene and ethylene pendant-armed cross-bridged tetraazamacrocycles and in vitro/in vivo comparisions of their copper(II) complexes. | 2011 | Inorg Chem | pmid:21381676 |
Li SY et al. | Inherently chiral calixarenes: synthesis, optical resolution, chiral recognition and asymmetric catalysis. | 2011 | Int J Mol Sci | pmid:21339996 |
Hoye TR et al. | Allylmalonate as an activator subunit for the initiation of relay ring-closing metathesis reactions. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21344570 |
Wu L et al. | Comparative metaproteomic analysis on consecutively Rehmannia glutinosa-monocultured rhizosphere soil. | 2011 | PLoS ONE | pmid:21655235 |
Psychogios N et al. | The human serum metabolome. | 2011 | PLoS ONE | pmid:21359215 |
Lim S et al. | D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. | 2011 | PLoS ONE | pmid:21931779 |
de Graaf RM et al. | The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. | 2011 | Mol. Biol. Evol. | pmid:21378103 |
Zhao Y et al. | Two- and three-dimensional silver(I)-organic networks generated from mono- and dicarboxylphenylethynes. | 2011 | Inorg Chem | pmid:21859129 |