Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shi D et al. | A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris. | 2011 | PLoS ONE | pmid:22174908 |
Schiff M et al. | Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin mice. | 2011 | PLoS ONE | pmid:22174907 |
Bauwens M et al. | Radioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers. | 2012 | PLoS ONE | pmid:22719886 |
Chojkier M et al. | Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study. | 2012 | PLoS ONE | pmid:22412837 |
Buck M | Direct infection and replication of naturally occurring hepatitis C virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures. | 2008 | PLoS ONE | pmid:18628977 |
Damrauer SM et al. | A20 modulates lipid metabolism and energy production to promote liver regeneration. | 2011 | PLoS ONE | pmid:21437236 |
Marreddy RK et al. | Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. | 2010 | PLoS ONE | pmid:20436673 |
Chanumolu SK et al. | UniDrug-target: a computational tool to identify unique drug targets in pathogenic bacteria. | 2012 | PLoS ONE | pmid:22431985 |
Tomita Y et al. | Genome and transcriptome analysis of the food-yeast Candida utilis. | 2012 | PLoS ONE | pmid:22629373 |
Thein M et al. | DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates. | 2012 | PLoS ONE | pmid:22590556 |