Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Li J et al. | Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6. | 2013 | Protein Cell | pmid:23807634 |
Scheer JM et al. | Malonate-assisted purification of human caspases. | 2005 | Protein Expr. Purif. | pmid:15802232 |
Maertens B et al. | Gene optimization mechanisms: a multi-gene study reveals a high success rate of full-length human proteins expressed in Escherichia coli. | 2010 | Protein Sci. | pmid:20506237 |
McPherson A | A comparison of salts for the crystallization of macromolecules. | 2001 | Protein Sci. | pmid:11266627 |
Jung JW et al. | The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies. | 2000 | Protein Sci. | pmid:10933494 |
Nam KH et al. | Insight into the antibacterial drug design and architectural mechanism of peptide recognition from the E. faecium peptide deformylase structure. | 2009 | Proteins | pmid:18831047 |
Dharmarajan L et al. | Structure of an archaeal-type phosphoenolpyruvate carboxylase sensitive to inhibition by aspartate. | 2011 | Proteins | pmid:21491491 |
Hariharan M and Allewell NM | Effects of the T-->R transition on the electrostatic properties of E. coli aspartate transcarbamylase. | 1998 | Proteins | pmid:9714159 |
Sivagnanam K et al. | Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose. | 2011 | Proteome Sci | pmid:22008648 |
Okoli AS et al. | Effects of human and porcine bile on the proteome of Helicobacter hepaticus. | 2012 | Proteome Sci | pmid:22533459 |