Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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McDowell EM | Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. A morphological and histochemical study of the pars recta during malonate poisoning. | 1974 | Virchows Arch B Cell Pathol | pmid:4210043 |
Giurov B | [Biochemical characteristics of the causative agent of fowl typhoid]. | 1986 | Vet Med Nauki | pmid:3765371 |
Dosch W | Rapid and direct gas chromatographic determination of oxalic acid in urine. | 1979 | Urol. Res. | pmid:505684 |
Zinich VN and Zobova NV | [Activation of succinate oxidase in the inner membrane of rat liver mitochondria]. | 1989 May-Jun | Ukr. Biokhim. Zh. | pmid:2546308 |
Davydov VV | [Metabolism of free malonic acid in rat tissues]. | 1991 Jan-Feb | Ukr. Biokhim. Zh. | pmid:2028517 |
Davydov VV et al. | [The effect of malonate on lipid biosynthesis in the liver]. | 1992 Nov-Dec | Ukr. Biokhim. Zh. | pmid:1488816 |
Mandrik KA et al. | [Kinetics of the inhibition of succinate dehydrogenase in bull adrenal cortex by malonate and oxaloacetate]. | 1983 Sep-Oct | Ukr. Biokhim. Zh. | pmid:6636310 |
Akopova OV et al. | [Estimation of ATP-dependent K(+)-channel contribution to potential-dependent potassium uptake in the rat brain mitochondria]. | 2014 Jan-Feb | Ukr Biochem J | pmid:24834715 |
Davydov VV and FreÄdin MI | [The effect of malonic acid on the rate of fibroblast proliferation in culture]. | 1993 | Tsitologiia | pmid:8322417 |
Bufetov EN et al. | [Effect of malonate on the structural and functional changes of wheat Triticum aestivum L. root cells]. | 2004 | Tsitologiia | pmid:15704878 |