Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Neoplasms D009369 13 associated lipids
Bacterial Infections D001424 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Abscess D000038 13 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Alzheimer Disease D000544 76 associated lipids
Teratoma D013724 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Nervous System Diseases D009422 37 associated lipids
Brain Edema D001929 20 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Nerve Degeneration D009410 53 associated lipids
Fever D005334 35 associated lipids
Catalepsy D002375 30 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Parkinson Disease D010300 53 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Insulin Resistance D007333 99 associated lipids
Memory Disorders D008569 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Neoplasms, Muscle Tissue D009379 2 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Schurr A and Gozal E Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress. 2011 Front Pharmacol pmid:22275901
Liu D Poly[[μ(2)-1,2-bis-(4-pyrid-yl)ethene](μ(3)-1,3-phenyl-enediacetato)-cadmium]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219828
Li ZS and Ng SW catena-Poly[[[(2,2'-bipyridine-κN,N')cobalt(II)]-μ-(E)-3,3'-(but-2-ene-2,3-di-yl)dibenzoato-κO,O':O'',O'''] hemihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219789
Jiang GQ et al. Hexa-μ(2)-acetato-κO:O'-(azido-κN)bis-(methanol-κO)-μ(3)-oxido-trichromium(III) methanol monosolvate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219738
Myking S et al. Candidate gene analysis of spontaneous preterm delivery: new insights from re-analysis of a case-control study using case-parent triads and control-mother dyads. 2011 BMC Med. Genet. pmid:22208904
Guo HM 5-tert-Butyl 3-ethyl 1-isopropyl-4,5,6,7-tetra-hydro-1H-pyrazolo-[4,3-c]pyridine-3,5-dicarboxyl-ate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22199750
Chen HR et al. Poly[[tetra-aqua-μ(4)-fumarato-di-μ(3)-fumarato-dineodymium(III)] trihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22199526
Shi D et al. A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris. 2011 PLoS ONE pmid:22174908
Schiff M et al. Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin mice. 2011 PLoS ONE pmid:22174907
Montavon TJ et al. Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers. 2011 Nat Chem pmid:22169871
Hench J et al. A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. 2011 PLoS ONE pmid:22162770
Singh SK et al. Coal Depolymerising Activity and Haloperoxidase Activity of Mn Peroxidase from Fomes durissimus MTCC-1173. 2011 Bioinorg Chem Appl pmid:22162670
Paul D et al. Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. 2011 PLoS ONE pmid:21386900
Fejes A et al. Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives. 2011 Curr Neuropharmacol pmid:22131946
Park SR et al. Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering. 2011 J. Microbiol. Biotechnol. pmid:22127124
Miller SE et al. The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. 2011 Cell pmid:22118466
Lallous N et al. The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers. 2011 PLoS ONE pmid:22096602
Quarrie R et al. Ischemic preconditioning decreases mitochondrial proton leak and reactive oxygen species production in the postischemic heart. 2011 J. Surg. Res. pmid:21035133
Hidaka M and Yoshida R Self-oscillating gel composed of thermosensitive polymer exhibiting higher LCST. 2011 J Control Release pmid:21130818
Padalkar VS et al. Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding. 2011 Chem Cent J pmid:22067202
Walash MI et al. Determination of oxybutynin in pharmaceuticals via reaction with mixed acids anhydrides: application to content uniformity testing. 2011 J Fluoresc pmid:21046437
Li Z 4,4'-[p-Phenyl-enebis(-oxy)]dibutanoic acid. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22065827
Guo HM 6-Benzyl 4-ethyl 2-chloro-5,6,7,8-tetra-hydro-pyrido[4,3-d]pyrimidine-4,6-di-carboxyl-ate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22065115
Deng YF Poly[[[μ(3)-5-(pyridine-4-carboxamido)-isophthalato]{μ(3)-5-[(pyridin-1-ium-4-yl)carbonyl-amino]-isophthalato}-neodymium(III)] dihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22058886
Troxell B et al. The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets. 2011 BMC Microbiol. pmid:22017966
Merlino A et al. Improving protein crystal quality by the without-oil microbatch method: crystallization and preliminary X-ray diffraction analysis of glutathione synthetase from Pseudoalteromonas haloplanktis. 2011 Int J Mol Sci pmid:22016660
Sivagnanam K et al. Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose. 2011 Proteome Sci pmid:22008648
Pon J et al. Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control. 2011 Malar. J. pmid:22029897
Rajeev L et al. Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium. 2011 Genome Biol. pmid:21992415
Li C and Zhou HM The role of manganese superoxide dismutase in inflammation defense. 2011 Enzyme Res pmid:21977313
Wang DZ et al. Homology-Driven Proteomics of Dinoflagellates with Unsequenced Genomes Using MALDI-TOF/TOF and Automated De Novo Sequencing. 2011 Evid Based Complement Alternat Med pmid:21977052
Hamby SE et al. In Silico identification of pathogenic strains of Cronobacter from Biochemical data reveals association of inositol fermentation with pathogenicity. 2011 BMC Microbiol. pmid:21933417
Phan I et al. Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. 2011 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:21904061
Abendroth J et al. BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis. 2011 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:21904058
Qiu G et al. Efficient assembly of 1-(1H-imidazol-1-yl)-3-methylene-1H-indenes via tandem reaction of (2-(alkynyl)benzylidene)malonates with imidazoles. 2011 ACS Comb Sci pmid:21247119
Ojha B and Das G Role of hydrophobic and polar interactions for BSA-amphiphile composites. 2011 Chem. Phys. Lipids pmid:21185815
Prakash M et al. Crystal growth, structural, optical, dielectric and thermal studies of an amino acid based organic NLO material: L-phenylalanine L-phenylalaninium malonate. 2011 Spectrochim Acta A Mol Biomol Spectrosc pmid:21943710
Rogers GW et al. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. 2011 PLoS ONE pmid:21799747
Garcia-Fernandez M et al. Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats. 2011 J Transl Med pmid:21798010
Holder JW et al. Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development. 2011 PLoS Genet. pmid:21931557
Xi ZX et al. Brain cannabinoid CBâ‚‚ receptors modulate cocaine's actions in mice. 2011 Nat. Neurosci. pmid:21785434
Di Bella S et al. Salmonella enterica ssp. arizonae infection in a 43-year-old Italian man with hypoglobulinemia: a case report and review of the literature. 2011 J Med Case Rep pmid:21781321
Zhao W et al. Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis. 2011 Mol Neurodegener pmid:21771318
Zeng WL 3-(2,4-Dichloro-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21754756
Zeng WL 5-(3,4-Dimethyl-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21754745
Sy A et al. Poly[di-μ-aqua-diaqua-di-μ(6)-malonato-cobalt(II)dipotassium(I)]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21754320
Zhou YH Di-μ-glutarato-κO:O-bis-[aqua-(1,10-phenanthroline-κN,N')copper(II)]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21753943
Hutcheson SW et al. Carbohydrase systems of Saccharophagus degradans degrading marine complex polysaccharides. 2011 Mar Drugs pmid:21731555
Lim IT and Choi KY One-dimensional hydrogen-bonded infinite chain from nickel(II) tetraaza macrocyclic complex and 1,2-cyclopentanedicarboxylate ligand. 2011 Int J Mol Sci pmid:21731438
Brand MD and Nicholls DG Assessing mitochondrial dysfunction in cells. 2011 Biochem. J. pmid:21726199
Hsieh YC et al. MPP(+)-induced toxicity in the presence of dopamine is mediated by COX-2 through oxidative stress. 2011 Naunyn Schmiedebergs Arch. Pharmacol. pmid:21667279
Treberg JR et al. Evidence for two sites of superoxide production by mitochondrial NADH-ubiquinone oxidoreductase (complex I). 2011 J. Biol. Chem. pmid:21659507
Mamtimin B et al. Plasma metabonomic analysis with ¹H nuclear magnetic resonance revealing the relationship of different tumors and the disease homology theory of traditional Uyghur medicine. 2011 Chin J Integr Med pmid:21390577
Lillehoj HS et al. Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens. 2011 BMC Proc pmid:21645315
Lin S and Cronan JE Closing in on complete pathways of biotin biosynthesis. 2011 Mol Biosyst pmid:21437340
Eloe EA et al. Going deeper: metagenome of a hadopelagic microbial community. 2011 PLoS ONE pmid:21629664
Vajpayee V et al. Self-assembled arene-ruthenium-based rectangles for the selective sensing of multi-carboxylate anions. 2011 Chemistry pmid:21611989
Wang YY and Tsay YF Arabidopsis nitrate transporter NRT1.9 is important in phloem nitrate transport. 2011 Plant Cell pmid:21571952
Zeng WL 3-(4-Fluoro-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21522968
Aghabozorg H et al. Bis(2-amino-4-methyl-pyridinium) bis-(pyridine-2,6-dicarboxyl-ato)cuprate(II). 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21522859
Zhao YY catena-Poly[[diaqua-cobalt(II)]-μ-4,4'-[1,4-phenyl-enebis(-oxy)]dibutano-ato-κO,O':O'',O''']. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21522824
Aghabozorg H et al. Bis(2,3-diamino-pyridinium) bis-(μ-pyridine-2,6-dicarboxyl-ato)-κO,N,O:O;κO:O,N,O-bis-[aqua-(pyridine-2,6-dicarboxyl-ato-κO,N,O)bis-muthate(III)] tetra-hydrate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21522286
Ringstrand B et al. The preparation of 3-substituted-1,5-dibromopentanes as precursors to heteracyclohexanes. 2011 Beilstein J Org Chem pmid:21512596
Cano KE et al. NMR-based metabolomic analysis of the molecular pathogenesis of therapy-related myelodysplasia/acute myeloid leukemia. 2011 J. Proteome Res. pmid:21510650
Dharmarajan L et al. Structure of an archaeal-type phosphoenolpyruvate carboxylase sensitive to inhibition by aspartate. 2011 Proteins pmid:21491491
Matar-Merheb R et al. Structuring detergents for extracting and stabilizing functional membrane proteins. 2011 PLoS ONE pmid:21483854
Sorokin DY et al. Culturable diversity of lithotrophic haloalkaliphilic sulfate-reducing bacteria in soda lakes and the description of Desulfonatronum thioautotrophicum sp. nov., Desulfonatronum thiosulfatophilum sp. nov., Desulfonatronovibrio thiodismutans sp. nov., and Desulfonatronovibrio magnus sp. nov. 2011 Extremophiles pmid:21479878
Zhao J et al. MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. 2011 Plant Cell pmid:21467581
Ling AS et al. A zinc finger protein, TbZC3H20, stabilizes two developmentally regulated mRNAs in trypanosomes. 2011 J. Biol. Chem. pmid:21467035
Gallo M et al. MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. 2011 PLoS ONE pmid:21448454
Kurakin A The self-organizing fractal theory as a universal discovery method: the phenomenon of life. 2011 Theor Biol Med Model pmid:21447162
Damrauer SM et al. A20 modulates lipid metabolism and energy production to promote liver regeneration. 2011 PLoS ONE pmid:21437236
Pryde KR and Hirst J Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer. 2011 J. Biol. Chem. pmid:21393237
Lo Iacono L et al. A carbon monoxide-releasing molecule (CORM-3) uncouples mitochondrial respiration and modulates the production of reactive oxygen species. 2011 Free Radic. Biol. Med. pmid:21382478
Antkiewicz-Michaluk L et al. Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release. 2011 Neurotox Res pmid:21069490
Wissler L et al. Back to the sea twice: identifying candidate plant genes for molecular evolution to marine life. 2011 BMC Evol. Biol. pmid:21226908
Facchinelli F and Weber AP The metabolite transporters of the plastid envelope: an update. 2011 Front Plant Sci pmid:22645538
Ramachandran VK et al. Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics. 2011 Genome Biol. pmid:22018401
Darandeh N and Hadavi E Effect of Pre-Harvest Foliar Application of Citric Acid and Malic Acid on Chlorophyll Content and Post-Harvest Vase Life of Lilium cv. Brunello. 2011 Front Plant Sci pmid:22639626
Takahashi H et al. Evolutionary relationships and functional diversity of plant sulfate transporters. 2011 Front Plant Sci pmid:22629272
Iacopetta D et al. A novel subfamily of mitochondrial dicarboxylate carriers from Drosophila melanogaster: biochemical and computational studies. 2011 Biochim. Biophys. Acta pmid:21130726
Hering-Smith KS et al. Calcium sensitivity of dicarboxylate transport in cultured proximal tubule cells. 2011 Am. J. Physiol. Renal Physiol. pmid:21123491
Pagani I et al. Complete genome sequence of Marivirga tractuosa type strain (H-43). 2011 Stand Genomic Sci pmid:21677852
Tomasiak TM et al. Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase. 2011 J. Biol. Chem. pmid:21098488
Lejon S et al. Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. 2011 J. Biol. Chem. pmid:21047798
Odendaal AY et al. Isomeric trimethylene and ethylene pendant-armed cross-bridged tetraazamacrocycles and in vitro/in vivo comparisions of their copper(II) complexes. 2011 Inorg Chem pmid:21381676
Li SY et al. Inherently chiral calixarenes: synthesis, optical resolution, chiral recognition and asymmetric catalysis. 2011 Int J Mol Sci pmid:21339996
Hoye TR et al. Allylmalonate as an activator subunit for the initiation of relay ring-closing metathesis reactions. 2011 Angew. Chem. Int. Ed. Engl. pmid:21344570
Wu L et al. Comparative metaproteomic analysis on consecutively Rehmannia glutinosa-monocultured rhizosphere soil. 2011 PLoS ONE pmid:21655235
Kim SH et al. Metabolic profiling and predicting the free radical scavenging activity of guava (Psidium guajava L.) leaves according to harvest time by 1H-nuclear magnetic resonance spectroscopy. 2011 Biosci. Biotechnol. Biochem. pmid:21670527
Psychogios N et al. The human serum metabolome. 2011 PLoS ONE pmid:21359215
Bräutigam A et al. An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species. 2011 Plant Physiol. pmid:20543093
Amoêdo ND et al. Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. 2011 PLoS ONE pmid:21789245
Lim S et al. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. 2011 PLoS ONE pmid:21931779
de Graaf RM et al. The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. 2011 Mol. Biol. Evol. pmid:21378103
Edwards TE et al. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. 2011 BMC Struct. Biol. pmid:21995815
Li JV et al. Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections. 2011 Am. J. Trop. Med. Hyg. pmid:21212208
Wang YQ et al. Manganese(II)-carboxylate-pseudohalide systems derived from 1,4-bis(4-carboxylatopyridinium-1-methylene)benzene: structures and magnetism. 2011 Dalton Trans pmid:21915428
Bondia-Pons I et al. Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. 2011 Nutr J pmid:22011443
Zhao Y et al. Two- and three-dimensional silver(I)-organic networks generated from mono- and dicarboxylphenylethynes. 2011 Inorg Chem pmid:21859129