Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gougoux A et al. | Maleate-induced bicarbonaturia in the dog: a carbonic anhydrase-independene effect. | 1976 | Am. J. Physiol. | pmid:10734 |
Uyemura SA et al. | Oxidative phosphorylation, Ca(2+) transport, and fatty acid-induced uncoupling in malaria parasites mitochondria. | 2000 | J. Biol. Chem. | pmid:10734123 |
Moy LY et al. | Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures. | 2000 | J. Neurochem. | pmid:10737624 |
Guidetti P et al. | In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum. | 2000 | Exp. Neurol. | pmid:10785450 |
Lin LZ et al. | Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. membranaceus. | 2000 | J Chromatogr A | pmid:10823504 |
Bew SP et al. | Kinetic resolution of alpha-acetoxy carboxylic acids with homochiral SuperQuats. | 2000 | Chirality | pmid:10824175 |
Sett S et al. | Avirulent mutants of Macrophomina phaseolina and Aspergillus fumigatus initiate infection in Phaseolus mungo in the presence of phaseolinone; levamisole gives protection. | 2000 | J. Biosci. | pmid:10824201 |
Kuijt J et al. | Quenched phosphorescence, a new detection method in capillary electrophoresis. | 2000 | Electrophoresis | pmid:10826674 |
Koo HM and Kim YS | Identification of active-site residues in Bradyrhizobium japonicum malonyl-coenzyme A synthetase. | 2000 | Arch. Biochem. Biophys. | pmid:10871057 |
Andreassen OA et al. | Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. | 2000 | J. Neurochem. | pmid:10899963 |