Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Guyot MC et al. | Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats. | 1997 | Neuroscience | pmid:9300407 |
Beal MF and Matthews RT | Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases. | 1997 | Mol. Aspects Med. | pmid:9266519 |
Garcia-Delgado GA et al. | A comparison of various Haemophilus somnus strains. | 1977 | Can. J. Comp. Med. | pmid:922555 |
Meigs RA and Sheean LA | Mitochondria from human term placenta. III. The role of respiration and energy generation in progesterone biosynthesis. | 1977 | Biochim. Biophys. Acta | pmid:922026 |
Hoenke S et al. | Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli. | 1997 | Eur. J. Biochem. | pmid:9208947 |
Yano S et al. | A new case of malonyl coenzyme A decarboxylase deficiency presenting with cardiomyopathy. | 1997 | Eur. J. Pediatr. | pmid:9177981 |
Wang R et al. | A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases. | 1997 | Bioorg. Med. Chem. | pmid:9158864 |
Magliozzo RS and Marcinkeviciene JA | The role of Mn(II)-peroxidase activity of mycobacterial catalase-peroxidase in activation of the antibiotic isoniazid. | 1997 | J. Biol. Chem. | pmid:9083004 |
Zeevalk GD et al. | In vivo vulnerability of dopamine neurons to inhibition of energy metabolism. | 1997 | Eur. J. Pharmacol. | pmid:9059843 |
Affourtit C et al. | Kinetic interaction between oxidases and dehydrogenases in plant mitochondria. | 1997 | Biochem. Soc. Trans. | pmid:9056958 |