Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alcorn T and Juers DH | Progress in rational methods of cryoprotection in macromolecular crystallography. | 2010 | Acta Crystallogr. D Biol. Crystallogr. | pmid:20382989 |
| RodrÃguez E et al. | Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. | 2010 | Int. J. Biol. Sci. | pmid:20440403 |
| Ivanova N et al. | Complete genome sequence of Gordonia bronchialis type strain (3410). | 2010 | Stand Genomic Sci | pmid:21304674 |
| Ojha B et al. | 2-Alkylmalonic acid: amphiphilic chelator and a potent inhibitor of metalloenzyme. | 2010 | J Phys Chem B | pmid:20669918 |
| Pope FD et al. | Studies of single aerosol particles containing malonic acid, glutaric acid, and their mixtures with sodium chloride. II. Liquid-state vapor pressures of the acids. | 2010 | J Phys Chem A | pmid:20799753 |
| Kalonia H et al. | Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats. | 2010 | Neuroscience | pmid:20813166 |
| Bermúdez E et al. | Mechanism of the organocatalyzed decarboxylative Knoevenagel-Doebner reaction. A theoretical study. | 2010 | J Phys Chem A | pmid:21105640 |
| Yaya AR et al. | Synthesis of 17 alpha-substituted ethynylestradiols: potential ligands for drug vectors. | 2010 | Steroids | pmid:20302883 |
| Seifert EL et al. | Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. | 2010 | PLoS ONE | pmid:20352092 |
| Galley HF | Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis. | 2010 | Crit Care | pmid:20804578 |
| Bujacz G et al. | Cryoprotection properties of salts of organic acids: a case study for a tetragonal crystal of HEW lysozyme. | 2010 | Acta Crystallogr. D Biol. Crystallogr. | pmid:20606259 |
| Xu Q et al. | Discovery and comparative profiling of microRNAs in a sweet orange red-flesh mutant and its wild type. | 2010 | BMC Genomics | pmid:20398412 |
| Wang YQ et al. | Diverse manganese(II) coordination polymers with mixed azide and zwitterionic dicarboxylate ligands: structure and magnetic properties. | 2010 | Inorg Chem | pmid:20095647 |
| Bazil JN et al. | Modeling mitochondrial bioenergetics with integrated volume dynamics. | 2010 | PLoS Comput. Biol. | pmid:20052270 |
| Kissen R et al. | Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. | 2010 | BMC Genomics | pmid:20307264 |
| Pope FD et al. | Studies of single aerosol particles containing malonic acid, glutaric acid, and their mixtures with sodium chloride. I. Hygroscopic growth. | 2010 | J Phys Chem A | pmid:20361768 |
| DiMauro S | Pathogenesis and treatment of mitochondrial myopathies: recent advances. | 2010 | Acta Myol | pmid:21314015 |
| Hara Y et al. | Molecular design and functional control of novel self-oscillating polymers. | 2010 | Int J Mol Sci | pmid:20386662 |
| Calkins MJ et al. | Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition. | 2010 | Toxicol. Sci. | pmid:20211941 |
| Lail K et al. | Complete genome sequence of Spirosoma linguale type strain (1). | 2010 | Stand Genomic Sci | pmid:21304700 |
| Liu B et al. | Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation. | 2010 | Mol. Cell. Biochem. | pmid:19851835 |
| Lee KY et al. | The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies. | 2010 | Microb. Cell Fact. | pmid:21092328 |
| Binukumar BK et al. | Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes. | 2010 | Mol Brain | pmid:21073741 |
| Li J et al. | A genome-wide association scan on estrogen receptor-negative breast cancer. | 2010 | Breast Cancer Res. | pmid:21062454 |
| Kök G et al. | The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose. | 2010 | Molecules | pmid:21042261 |
| Wu J et al. | Whole genome wide expression profiles of Vitis amurensis grape responding to downy mildew by using Solexa sequencing technology. | 2010 | BMC Plant Biol. | pmid:21029438 |
| Uemura T et al. | Unveiling thermal transitions of polymers in subnanometre pores. | 2010 | Nat Commun | pmid:20981011 |
| Kil DY et al. | Age and diet affect gene expression profiles in canine liver tissue. | 2010 | PLoS ONE | pmid:20967283 |
| Tang X et al. | Global gene profiling of laser-captured pollen mother cells indicates molecular pathways and gene subfamilies involved in rice meiosis. | 2010 | Plant Physiol. | pmid:20959420 |
| Frank S | Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease. | 2010 | Neuropsychiatr Dis Treat | pmid:20957126 |
| Dieng PS and Sirlin C | Recognition of chiral carboxylic anions by artificial receptors. | 2010 | Int J Mol Sci | pmid:20957098 |
| Nurmohamed S et al. | Molecular recognition between Escherichia coli enolase and ribonuclease E. | 2010 | Acta Crystallogr. D Biol. Crystallogr. | pmid:20823555 |
| Hou Y et al. | Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages. | 2010 | Proteome Sci | pmid:20822545 |
| Liu M et al. | Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel. | 2010 | Circ. Res. | pmid:20724705 |
| Taylor NL et al. | Analysis of the rice mitochondrial carrier family reveals anaerobic accumulation of a basic amino acid carrier involved in arginine metabolism during seed germination. | 2010 | Plant Physiol. | pmid:20720170 |
| Luang S et al. | Crystallisation of wild-type and variant forms of a recombinant plant enzyme β-D-glucan glucohydrolase from barley (Hordeum vulgare L.) and preliminary X-ray analysis. | 2010 | Int J Mol Sci | pmid:20717535 |
| Wingenter K et al. | Increased activity of the vacuolar monosaccharide transporter TMT1 alters cellular sugar partitioning, sugar signaling, and seed yield in Arabidopsis. | 2010 | Plant Physiol. | pmid:20709831 |
| Kagawa Y | ATP synthase: from single molecule to human bioenergetics. | 2010 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:20689227 |
| Hanin A et al. | Screening of in vivo activated genes in Enterococcus faecalis during insect and mouse infections and growth in urine. | 2010 | PLoS ONE | pmid:20686694 |
| Balk M et al. | (Per)chlorate reduction by an acetogenic bacterium, Sporomusa sp., isolated from an underground gas storage. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20680263 |
| Hagos Y and Wolff NA | Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity. | 2010 | Toxins (Basel) | pmid:22069672 |
| Bordel S et al. | Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes. | 2010 | PLoS Comput. Biol. | pmid:20657658 |
| Chakraborty B et al. | Stage specific developmental changes in the mitochondrial and surface membrane associated redox systems of Leishmania donovani promastigote and amastigote. | 2010 | Biochemistry Mosc. | pmid:20618140 |
| Marreddy RK et al. | Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. | 2010 | PLoS ONE | pmid:20436673 |
| Rey B et al. | Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. | 2010 | BMC Physiol. | pmid:20426850 |
| Miller MC et al. | Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis. | 2010 | Microbiology (Reading, Engl.) | pmid:20413552 |
| Rhee EP et al. | Metabolite profiling identifies markers of uremia. | 2010 | J. Am. Soc. Nephrol. | pmid:20378825 |
| Shimshek DR et al. | The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy. | 2010 | PLoS ONE | pmid:20368804 |
| Jha SS et al. | Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages. | 2010 | BMC Microbiol. | pmid:20359357 |
| el Khoury A and Atoui A | Ochratoxin a: general overview and actual molecular status. | 2010 | Toxins (Basel) | pmid:22069596 |
| Gauniya A et al. | Comparative bioavailability studies of citric acid and malonic acid based aspirin effervescent tablets. | 2010 | J Pharm Bioallied Sci | pmid:21814444 |
| Dolezal P et al. | The essentials of protein import in the degenerate mitochondrion of Entamoeba histolytica. | 2010 | PLoS Pathog. | pmid:20333239 |
| Wang YH et al. | Diastereoselective gamma-vinyl butyrolactone synthesis via gold catalyzed cyclization of allylic acetate. | 2010 | Chem. Commun. (Camb.) | pmid:20062867 |
| Varela C et al. | New structural and functional defects in polyphosphate deficient bacteria: a cellular and proteomic study. | 2010 | BMC Microbiol. | pmid:20067623 |
| Yoshida R | Design of self-oscillating gels and application to biomimetic actuators. | 2010 | Sensors (Basel) | pmid:22294901 |
| Li B and Wu LX | Poly[[hexa-aqua-(μ(2)-fumarato-κO,O:O,O)bis-(μ(3)-maleato-κO,O:O:O)disamarium(III)] hexa-hydrate]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589236 |
| Silva P et al. | catena-Poly[[triaqua-chlorido-μ(3)-malonato-cerium(III)] hemihydrate]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589218 |
| Zeng WL | (E)-2,2-Dimethyl-5-(3-phenyl-allyl-idene)-1,3-dioxane-4,6-dione. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589113 |
| Zeng WL et al. | 3-(4-Meth-oxy-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589023 |
| Zeng WL | 5-(4-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588707 |
| Zeng WL | 5-(4-Hy-droxy-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588666 |
| Quah CK et al. | 8-Hy-droxy-quinolinium 2-carb-oxy-acetate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588617 |
| Aiyub Z et al. | Tetra-μ-acetato-κO:O'-bis-[(N-ethyl-pyrimidin-2-amine)-copper(II)](Cu-Cu). | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588567 |
| Wu DH and Wu QQ | 4-Ethyl-anilinium 2-carb-oxy-acetate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588444 |
| Meskini I et al. | Diethyl 2-[(3,5-dimethyl-1H-pyrazol-1-yl)(4-meth-oxy-phen-yl)meth-yl]propane-dioate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588286 |
| Wu J et al. | Metabolic changes reveal the development of schistosomiasis in mice. | 2010 | PLoS Negl Trop Dis | pmid:20824219 |
| Dobritsa AA et al. | LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. | 2010 | Plant Physiol. | pmid:20442277 |
| Win YF et al. | Poly[[aquadi-μ(3)-malonato-hexaphenyl-ditin(IV)] acetone solvate]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579332 |
| Chen YM and Xie QF | [Malonato(2-)-κO,O']bis-(1,10-phenanthroline-κN,N')zinc(II) penta-hydrate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522585 |
| Guo ML et al. | Poly[tetra-aqua-di-μ(4)-malonato-barium(II)cadmium(II)]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522548 |
| Guo ML | Poly[diaqua-μ(3)-4-nitro-phthalato-copper(II)]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522547 |
| Guo ML et al. | Poly[[μ(2)-aqua-tetraaquadi-μ(3)-malonato-nickel(II)strontium(II)] dihydrate]. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522545 |
| Benedito VA et al. | Genomic inventory and transcriptional analysis of Medicago truncatula transporters. | 2010 | Plant Physiol. | pmid:20023147 |
| Vieira N et al. | Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans. | 2010 | Mol. Microbiol. | pmid:19968788 |
| Demetrius LA et al. | Cancer proliferation and therapy: the Warburg effect and quantum metabolism. | 2010 | Theor Biol Med Model | pmid:20085650 |
| Scotti C et al. | Cell-cycle inhibition by Helicobacter pylori L-asparaginase. | 2010 | PLoS ONE | pmid:21085483 |
| Vaughan AM et al. | Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. | 2009 | Cell. Microbiol. | pmid:19068099 |
| Brown AK et al. | Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. | 2009 | PLoS ONE | pmid:19609444 |
| Casale A et al. | Sequestration of Alkyltin(IV) compounds in aqueous solution: formation, stability, and empirical relationships for the binding of dimethyltin(IV) cation by N- and O-donor ligands. | 2009 | Bioinorg Chem Appl | pmid:19590597 |
| Pistollato F et al. | Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. | 2009 | PLoS ONE | pmid:19587783 |
| Seppet E et al. | Mitochondria and energetic depression in cell pathophysiology. | 2009 | Int J Mol Sci | pmid:19564950 |
| Bryan CG et al. | Carbon and arsenic metabolism in Thiomonas strains: differences revealed diverse adaptation processes. | 2009 | BMC Microbiol. | pmid:19549320 |
| Kumasaka T et al. | Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. | 2009 | J. Biol. Chem. | pmid:19546224 |
| Tiziani S et al. | Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. | 2009 | PLoS ONE | pmid:19158949 |
| Zipse H et al. | Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. | 2009 | J. Am. Chem. Soc. | pmid:19128178 |
| Tran QT et al. | Chemical genomics of cancer chemopreventive dithiolethiones. | 2009 | Carcinogenesis | pmid:19126641 |
| Elliott JM et al. | Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation. | 2009 | J. Biol. Chem. | pmid:19117953 |
| Zeng WL et al. | 3-[(5-Methyl-furan-2-yl)methyl-ene]-1,5-dioxaspiro-[5.5]undecane-2,4-dione. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583701 |
| Zeng WL and Jian FF | 3-(2-Furylmethyl-ene)-1,5-dioxaspiro-[5.5]undecane-2,4-dione. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583569 |
| Soleimannejad J et al. | Poly[μ(2)-aqua-aqua-μ(4)-pyridine-2,4-dicarboxyl-ato-strontium]. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583378 |
| Burow LC et al. | Anaerobic central metabolic pathways active during polyhydroxyalkanoate production in uncultured cluster 1 Defluviicoccus enriched in activated sludge communities. | 2009 | FEMS Microbiol. Lett. | pmid:19622073 |
| Tsubogo T et al. | Chiral calcium catalysts with neutral coordinative ligands: enantioselective 1,4-addition reactions of 1,3-dicarbonyl compounds to nitroalkenes. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19862785 |
| Schmelz S et al. | AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. | 2009 | Nat. Chem. Biol. | pmid:19182782 |
| Dalla-Betta P and Schulte M | Calculation of the aqueous thermodynamic properties of citric acid cycle intermediates and precursors and the estimation of high temperature and pressure equation of state parameters. | 2009 | Int J Mol Sci | pmid:19582231 |
| Azuma Y and Ota M | An evaluation of minimal cellular functions to sustain a bacterial cell. | 2009 | BMC Syst Biol | pmid:19943949 |
| Tan Y et al. | Effects of precursor concentration and acidic sulfate in aqueous glyoxal-OH radical oxidation and implications for secondary organic aerosol. | 2009 | Environ. Sci. Technol. | pmid:19924930 |
| Spinks D et al. | Investigation of trypanothione reductase as a drug target in Trypanosoma brucei. | 2009 | ChemMedChem | pmid:19924760 |
| Pin C et al. | Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase. | 2009 | BMC Syst Biol | pmid:19917103 |
| Bar NS and Radde N | Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model. | 2009 | BMC Syst Biol | pmid:19903354 |
| Senoglu M et al. | Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve. | 2009 | J Brachial Plex Peripher Nerve Inj | pmid:19939272 |