Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lançar-Benba J et al. | Purification of the rat-liver mitochondrial dicarboxylate carrier by affinity chromatography on immobilized malate dehydrogenase. | 1994 | Biochim. Biophys. Acta | pmid:8142418 |
| Nikiforov AA and Ostretsova IB | Stimulation of weak organic acid uptake in rat renal tubules by cadmium and nystatin. | 1994 | Biochem. Pharmacol. | pmid:8135857 |
| Tassani V et al. | Anaplerotic effect of propionyl carnitine in rat heart mitochondria. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8135845 |
| Beattie DS et al. | Oxidation of NADH by a rotenone and antimycin-sensitive pathway in the mitochondrion of procyclic Trypanosoma brucei brucei. | 1994 | Mol. Biochem. Parasitol. | pmid:8078526 |
| Henshaw R et al. | Malonate produces striatal lesions by indirect NMDA receptor activation. | 1994 | Brain Res. | pmid:8069700 |
| Boland NI et al. | Characterization of follicular energy metabolism. | 1994 | Hum. Reprod. | pmid:8046010 |
| Reiss U and Rothstein M | Age-related changes in isocitrate lyase from the free living nematode, Turbatrix aceti. | 1975 | J. Biol. Chem. | pmid:803500 |
| Beal MF et al. | Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. | 1994 | Ann. Neurol. | pmid:7998775 |
| Ray S et al. | Inhibition of electron flow through complex I of the mitochondrial respiratory chain of Ehrlich ascites carcinoma cells by methylglyoxal. | 1994 | Biochem. J. | pmid:7945267 |
| Kim YS and Kim EJ | A plasmid responsible for malonate assimilation in Pseudomonas fluorescens. | 1994 | Plasmid | pmid:7846146 |
| Brand MD et al. | The sum of flux control coefficients in the electron-transport chain of mitochondria. | 1994 | Eur. J. Biochem. | pmid:7813471 |
| Oldendorf WH et al. | Transient blood-brain barrier passage of polar compounds at low pH. | 1994 | Am. J. Physiol. | pmid:7810722 |
| Nieva-Gomez D and Konisky J | Membrane changes in Escherichia coli induced by colicin Ia and agents known to disrupt energy transduction. | 1976 | Biochemistry | pmid:779829 |
| Kirschner PB et al. | Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats. | 1995 | J. Cereb. Blood Flow Metab. | pmid:7790410 |
| Klein BY et al. | Analysis of cell-mediated mineralization in culture of bone-derived embryonic cells with neurofibromatosis. | 1995 | J. Cell. Biochem. | pmid:7768987 |
| Ermayanti TM et al. | Stimulation of synthesis and release of swainosonine from transformed roots of Swainsona galegifolia. | 1994 | Phytochemistry | pmid:7764877 |
| Dehning I and Schink B | Anaerobic degradation of malonate via malonyl-CoA by Sporomusa malonica, Klebsiella oxytoca, and Rhodobacter capsulatus. | 1994 | Antonie Van Leeuwenhoek | pmid:7710283 |
| Schuster H et al. | Substrate and product binding sites of yeast fatty acid synthase. Stoichiometry and binding kinetics of wild-type and in vitro mutated enzymes. | 1995 | Eur. J. Biochem. | pmid:7705357 |
| Davydov VV et al. | [Effect of malonate on various aspects of hepatic metabolism]. | 1994 Oct-Dec | Patol Fiziol Eksp Ter | pmid:7700705 |
| Byun HS and Kim YS | Assays for malonate decarboxylase. | 1994 | Anal. Biochem. | pmid:7695096 |