Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Andreassen OA et al. | Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. | 2001 | Exp. Neurol. | pmid:11161607 |
Van Westerlaak MG et al. | Chronic mitochondrial inhibition induces glutamate-mediated corticomotoneuron death in an organotypic culture model. | 2001 | Exp. Neurol. | pmid:11161628 |
Piasecka M et al. | Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. | 2001 | Andrologia | pmid:11167513 |
Mossakowski MJ et al. | Effect of sodium glutamate on the morphology and histochemistry of experimental gliopathy induced in vitro by ammonia and sodium malonate. | 1975 Jan-Mar | Neuropatol Pol | pmid:1118055 |
Ruiz-Pérez C et al. | Magnetic coupling through the carbon skeleton of malonate in two polymorphs of ([Cu(bpy)(H2O)][Cu(bpy)(mal)(H2O)])(ClO4)2 (H2mal = malonic acid; bpy = 2,2'-bipyridine). | 2000 | Inorg Chem | pmid:11196779 |
Meldrum A et al. | Role of corticostriatal and nigrostriatal inputs in malonate-induced striatal toxicity. | 2001 | Neuroreport | pmid:11201098 |
pmid:11211254 | ||||
Matharu A et al. | Contributions of the substrate-binding arginine residues to maleate-induced closure of the active site of Escherichia coli aspartate aminotransferase. | 2001 | Eur. J. Biochem. | pmid:11248682 |
Lancaster CR et al. | A third crystal form of Wolinella succinogenes quinol:fumarate reductase reveals domain closure at the site of fumarate reduction. | 2001 | Eur. J. Biochem. | pmid:11248702 |
Kavitha J and Subbaraju GV | Synthesis of N-[3,4-dimethoxyphenyl)propanoyl]pyrrole, a metabolite of Piper brachystachyum. | 2000 | J Asian Nat Prod Res | pmid:11252681 |