Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:17173413 | ||||
Li S and Li XJ | Multiple pathways contribute to the pathogenesis of Huntington disease. | 2006 | Mol Neurodegener | pmid:17173700 |
Saito N et al. | 7-Polyacylated delphinidin 3,7-diglucosides from the blue flowers of Leschenaultia cv. Violet Lena. | 2007 | Phytochemistry | pmid:17174991 |
Salomons GS et al. | Clinical, enzymatic and molecular characterization of nine new patients with malonyl-coenzyme A decarboxylase deficiency. | 2007 | J. Inherit. Metab. Dis. | pmid:17186413 |
Luvisetto S et al. | Tracking of proton flow during transition from anaerobiosis to steady state. 2. Effect of cation uptake on the response of a hydrophobic membrane bound pH indicator. | 1991 | Eur. J. Biochem. | pmid:1718751 |
Zhang D et al. | Synthesis of indenes by the transition metal-mediated carboannulation of alkynes. | 2007 | J. Org. Chem. | pmid:17194107 |
Watts RJ et al. | Enhanced stability of hydrogen peroxide in the presence of subsurface solids. | 2007 | J. Contam. Hydrol. | pmid:17196706 |
pmid:17201003 | ||||
Lockyer AE et al. | Biomphalaria glabrata transcriptome: identification of cell-signalling, transcriptional control and immune-related genes from open reading frame expressed sequence tags (ORESTES). | 2007 | Dev. Comp. Immunol. | pmid:17208299 |
pmid:17212363 | ||||
Han C et al. | Photo-induced cold vapor generation with low molecular weight alcohol, aldehyde, or carboxylic acid for atomic fluorescence spectrometric determination of mercury. | 2007 | Anal Bioanal Chem | pmid:17216165 |
Nilwarangkoon S et al. | Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway. | 2007 | J. Pharmacol. Sci. | pmid:17220594 |
pmid:17226942 | ||||
Young KC et al. | Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex. | 2007 | Neurobiol. Dis. | pmid:17240155 |
pmid:17249750 | ||||
pmid:17252210 | ||||
pmid:17253690 | ||||
pmid:17257042 | ||||
Fortner KC and Shair MD | Stereoelectronic effects dictate mechanistic dichotomy between Cu(II)-catalyzed and enzyme-catalyzed reactions of malonic acid half thioesters. | 2007 | J. Am. Chem. Soc. | pmid:17263375 |
pmid:17263433 | ||||
Schneider S et al. | Crystallization and X-ray diffraction analysis of the DNA-remodelling protein DnaD from Bacillus subtilis. | 2007 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:17277452 |
Mizuno Y et al. | Crystal structure of Arabidopsis PII reveals novel structural elements unique to plants. | 2007 | Biochemistry | pmid:17279613 |
Volonterio A and Zanda M | Three-component, one-pot sequential synthesis of N-aryl, N'-alkyl barbiturates. | 2007 | Org. Lett. | pmid:17284045 |
pmid:17285171 | ||||
pmid:17290467 | ||||
pmid:17291117 | ||||
pmid:17299645 | ||||
Ravcheev DA et al. | Comparative genomic analysis of regulation of anaerobic respiration in ten genomes from three families of gamma-proteobacteria (Enterobacteriaceae, Pasteurellaceae, Vibrionaceae). | 2007 | BMC Genomics | pmid:17313674 |
pmid:17320475 | ||||
pmid:17335187 | ||||
pmid:17340670 | ||||
Tucker DL et al. | Characterization of Escherichia coli MG1655 grown in a low-shear modeled microgravity environment. | 2007 | BMC Microbiol. | pmid:17343762 |
Turner P et al. | Potential and utilization of thermophiles and thermostable enzymes in biorefining. | 2007 | Microb. Cell Fact. | pmid:17359551 |
Josyula AB et al. | Reduction in urinary arsenic with bottled-water intervention. | 2006 | J Health Popul Nutr | pmid:17366771 |
Ghosh AK et al. | Syntheses, crystal structures, and magnetic properties of metal-organic hybrid materials of Cu(II): effect of a long chain dicarboxylate backbone, and counteranion in their structural diversity. | 2007 | Inorg Chem | pmid:17373784 |
pmid:17385924 | ||||
Diener MD et al. | (212)Pb@C(60) and its water-soluble derivatives: synthesis, stability, and suitability for radioimmunotherapy. | 2007 | J. Am. Chem. Soc. | pmid:17394315 |
pmid:17405177 | ||||
Neretti N et al. | Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation. | 2007 | BMC Bioinformatics | pmid:17430560 |
Iversen C et al. | The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cronobacter dublinensis sp. nov. and Cronobacter genomospecies 1. | 2007 | BMC Evol. Biol. | pmid:17439656 |
pmid:17441070 | ||||
pmid:17442340 | ||||
Plush SE and Gunnlaugsson T | Luminescent sensing of dicarboxylates in water by a bismacrocyclic dinuclear Eu(III) conjugate. | 2007 | Org. Lett. | pmid:17447771 |
Aliverdieva DA et al. | Topography of the active site of the Saccharomyces cerevisiae plasmalemmal dicarboxylate transporter studied using lipophilic derivatives of its substrates. | 2007 | Biochemistry Mosc. | pmid:17447879 |
Wang GW and Li FB | Radical reactions of [60]fullerene mediated by manganese(III) acetate dihydrate. | 2007 Apr-May | J Nanosci Nanotechnol | pmid:17450885 |
Ostrow JD and Mukerjee P | Revalidation and rationale for high pKa values of unconjugated bilirubin. | 2007 | BMC Biochem. | pmid:17475001 |
pmid:17477523 | ||||
Chojnacki H | Proton transfer in some periodic molecular systems. | 2007 | J Mol Model | pmid:17479303 |
pmid:17488034 | ||||
Devereux M et al. | Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine). | 2006 | Bioinorg Chem Appl | pmid:17497019 |
pmid:17497909 | ||||
Puntel RL et al. | Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates. | 2007 | Life Sci. | pmid:17532009 |
Malvagia S et al. | Fatal malonyl CoA decarboxylase deficiency due to maternal uniparental isodisomy of the telomeric end of chromosome 16. | 2007 | Ann. Hum. Genet. | pmid:17535268 |
pmid:17550226 | ||||
Creaven BS et al. | Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenanthroline). | 2007 | J. Inorg. Biochem. | pmid:17555821 |
Schurr A and Payne RS | Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. | 2007 | Neuroscience | pmid:17560727 |
Himeno S et al. | Simultaneous determination of phosphonate, phosphate, and diphosphate by capillary electrophoresis using in-capillary complexation with Mo(VI). | 2007 | J Sep Sci | pmid:17566343 |
pmid:17567097 | ||||
Kim HI and Beauchamp JL | Cluster phase chemistry: collisions of vibrationally excited cationic dicarboxylic acid clusters with water molecules initiate dissociation of cluster components. | 2007 | J Phys Chem A | pmid:17569511 |
Fan R et al. | Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates. | 2007 | J. Org. Chem. | pmid:17585824 |
Chiu KP et al. | Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. | 2007 | BMC Cancer | pmid:17594473 |
Schwartz JM et al. | Observing metabolic functions at the genome scale. | 2007 | Genome Biol. | pmid:17594483 |
pmid:17604051 | ||||
Koponen IK et al. | Thermodynamic properties of malonic, succinic, and glutaric acids: evaporation rates and saturation vapor pressures. | 2007 | Environ. Sci. Technol. | pmid:17612170 |
Cinti DL et al. | Biochemical properties of rat liver mitochondrial aldehyde dehydrogenase with respect to oxidation of formaldehyde. | 1976 | J. Biol. Chem. | pmid:176156 |
pmid:17616229 | ||||
Carbone I et al. | Gene duplication, modularity and adaptation in the evolution of the aflatoxin gene cluster. | 2007 | BMC Evol. Biol. | pmid:17620135 |
pmid:17622422 | ||||
Karki S et al. | Powder X-ray diffraction as an emerging method to structurally characterize organic solids. | 2007 | Org. Lett. | pmid:17629292 |
Deguchi Y et al. | Transcriptome profiling of Lotus japonicus roots during arbuscular mycorrhiza development and comparison with that of nodulation. | 2007 | DNA Res. | pmid:17634281 |
Yip SF et al. | Room-temperature copper-catalyzed alpha-arylation of malonates. | 2007 | Org. Lett. | pmid:17637034 |
Pohl T et al. | Effects of the deletion of the Escherichia coli frataxin homologue CyaY on the respiratory NADH:ubiquinone oxidoreductase. | 2007 | BMC Biochem. | pmid:17650323 |
Mochel F et al. | Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. | 2007 | PLoS ONE | pmid:17653274 |
Shevela D et al. | Interactions of photosystem II with bicarbonate, formate and acetate. | Photosyn. Res. | pmid:17653834 | |
Panee J et al. | The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. | 2007 | Int. J. Biol. Sci. | pmid:17657281 |
pmid:17658772 | ||||
Dutertre S et al. | AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. | 2007 | EMBO J. | pmid:17660751 |
pmid:17667748 | ||||
Mailloux RJ et al. | The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. | 2007 | PLoS ONE | pmid:17668068 |
Epstein IR et al. | Coupled and forced patterns in reaction-diffusion systems. | 2008 | Philos Trans A Math Phys Eng Sci | pmid:17673412 |
D'Amelio M et al. | The apoptosome: emerging insights and new potential targets for drug design. | 2008 | Pharm. Res. | pmid:17674158 |
Lubkoll J and Wennemers H | Mimicry of polyketide synthases--enantioselective 1,4-addition reactions of malonic acid half-thioesters to nitroolefins. | 2007 | Angew. Chem. Int. Ed. Engl. | pmid:17680584 |
pmid:17691722 | ||||
pmid:17691784 | ||||
pmid:17696494 | ||||
pmid:17704772 | ||||
Vindal V et al. | GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. | 2007 | BMC Genomics | pmid:17714599 |
pmid:17723601 | ||||
Kenney WC et al. | Localization of the substrate and oxalacetate binding site of succinate dehydrogenase. | 1976 | J. Biol. Chem. | pmid:177411 |
Lovell TM et al. | Identification of a novel mammalian post-translational modification, phosphocholine, on placental secretory polypeptides. | 2007 | J. Mol. Endocrinol. | pmid:17766644 |
Müller SC et al. | The structure of the core of the spiral wave in the belousov-zhabotinskii reaction. | 1985 | Science | pmid:17797290 |
pmid:17828366 | ||||
Winfree AT | Scroll-shaped waves of chemical activity in three dimensions. | 1973 | Science | pmid:17835842 |
Chisholm MH | Mixed valence complexes involving MM quadruple bonds (M=Mo or W). | 2008 | Philos Trans A Math Phys Eng Sci | pmid:17846014 |
pmid:17850154 | ||||
Cao X et al. | Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology. | 2007 | BMC Neurosci | pmid:17868476 |
pmid:17883266 | ||||
Cerar J et al. | Analysis of sample of highly water-soluble Th-symmetric fullerenehexamalonic acid C66(COOH)12 by ion-chromatography and capillary electrophoresis. | 2007 | J Chromatogr A | pmid:17888933 |
pmid:17889996 | ||||
Davydov VV and Repetskaia AV | [Protective effect of malonic acid in hypoxic hypoxia]. | 1991 Sep-Oct | Fiziol Zh | pmid:1790806 |