Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Bacterial Infections D001424 21 associated lipids
Hyperglycemia D006943 21 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Brain Diseases D001927 27 associated lipids
Catalepsy D002375 30 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Memory Disorders D008569 33 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Aklujkar M et al. The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments. 2010 BMC Genomics pmid:20828392
Alcorn T and Juers DH Progress in rational methods of cryoprotection in macromolecular crystallography. 2010 Acta Crystallogr. D Biol. Crystallogr. pmid:20382989
Rodríguez E et al. Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. 2010 Int. J. Biol. Sci. pmid:20440403
Ojha B et al. 2-Alkylmalonic acid: amphiphilic chelator and a potent inhibitor of metalloenzyme. 2010 J Phys Chem B pmid:20669918
Pope FD et al. Studies of single aerosol particles containing malonic acid, glutaric acid, and their mixtures with sodium chloride. II. Liquid-state vapor pressures of the acids. 2010 J Phys Chem A pmid:20799753
Kalonia H et al. Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats. 2010 Neuroscience pmid:20813166
Bermúdez E et al. Mechanism of the organocatalyzed decarboxylative Knoevenagel-Doebner reaction. A theoretical study. 2010 J Phys Chem A pmid:21105640
Yaya AR et al. Synthesis of 17 alpha-substituted ethynylestradiols: potential ligands for drug vectors. 2010 Steroids pmid:20302883
Galley HF Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis. 2010 Crit Care pmid:20804578
Xu Q et al. Discovery and comparative profiling of microRNAs in a sweet orange red-flesh mutant and its wild type. 2010 BMC Genomics pmid:20398412
Bazil JN et al. Modeling mitochondrial bioenergetics with integrated volume dynamics. 2010 PLoS Comput. Biol. pmid:20052270
Taghavi S et al. Genome sequence of the plant growth promoting endophytic bacterium Enterobacter sp. 638. 2010 PLoS Genet. pmid:20485560
Pope FD et al. Studies of single aerosol particles containing malonic acid, glutaric acid, and their mixtures with sodium chloride. I. Hygroscopic growth. 2010 J Phys Chem A pmid:20361768
DiMauro S Pathogenesis and treatment of mitochondrial myopathies: recent advances. 2010 Acta Myol pmid:21314015
Cabral JP Water microbiology. Bacterial pathogens and water. 2010 Int J Environ Res Public Health pmid:21139855
Li S et al. Constructing a fish metabolic network model. 2010 Genome Biol. pmid:21114829
Lee KY et al. The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies. 2010 Microb. Cell Fact. pmid:21092328
Binukumar BK et al. Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes. 2010 Mol Brain pmid:21073741
Li J et al. A genome-wide association scan on estrogen receptor-negative breast cancer. 2010 Breast Cancer Res. pmid:21062454
Kobayashi S et al. Chiral zirconium complex as Brønsted base catalyst in asymmetric direct-type Mannich reactions. 2010 Chem Asian J pmid:20099294
Pisarenko AN et al. Rapid analysis of perchlorate, chlorate and bromate ions in concentrated sodium hypochlorite solutions. 2010 Anal. Chim. Acta pmid:20103127
Kök G et al. The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose. 2010 Molecules pmid:21042261
Smith MA et al. The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. 2010 J. Biol. Chem. pmid:20106978
Wu J et al. Whole genome wide expression profiles of Vitis amurensis grape responding to downy mildew by using Solexa sequencing technology. 2010 BMC Plant Biol. pmid:21029438
Uemura T et al. Unveiling thermal transitions of polymers in subnanometre pores. 2010 Nat Commun pmid:20981011
Cowen D et al. A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH. 2010 Bioorg. Med. Chem. Lett. pmid:20034791
Gao X et al. Engineered polyketide biosynthesis and biocatalysis in Escherichia coli. 2010 Appl. Microbiol. Biotechnol. pmid:20853106
Gong M et al. The evolutionary trajectory of mitochondrial carrier family during metazoan evolution. 2010 BMC Evol. Biol. pmid:20843381
Baek JG et al. Metabolite profiling of Cheonggukjang, a fermented soybean paste, inoculated with various Bacillus strains during fermentation. 2010 Biosci. Biotechnol. Biochem. pmid:20834151
Sripadi P et al. Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry. 2010 PLoS ONE pmid:20830293
Nurmohamed S et al. Molecular recognition between Escherichia coli enolase and ribonuclease E. 2010 Acta Crystallogr. D Biol. Crystallogr. pmid:20823555
Hou Y et al. Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages. 2010 Proteome Sci pmid:20822545
Liu M et al. Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel. 2010 Circ. Res. pmid:20724705
Taylor NL et al. Analysis of the rice mitochondrial carrier family reveals anaerobic accumulation of a basic amino acid carrier involved in arginine metabolism during seed germination. 2010 Plant Physiol. pmid:20720170
Luang S et al. Crystallisation of wild-type and variant forms of a recombinant plant enzyme β-D-glucan glucohydrolase from barley (Hordeum vulgare L.) and preliminary X-ray analysis. 2010 Int J Mol Sci pmid:20717535
Wingenter K et al. Increased activity of the vacuolar monosaccharide transporter TMT1 alters cellular sugar partitioning, sugar signaling, and seed yield in Arabidopsis. 2010 Plant Physiol. pmid:20709831
Kagawa Y ATP synthase: from single molecule to human bioenergetics. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20689227
Hanin A et al. Screening of in vivo activated genes in Enterococcus faecalis during insect and mouse infections and growth in urine. 2010 PLoS ONE pmid:20686694
Wanders RJ et al. The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. 2010 J. Inherit. Metab. Dis. pmid:20490924
Kellmann R et al. Biosynthesis and molecular genetics of polyketides in marine dinoflagellates. 2010 Mar Drugs pmid:20479965
Chhabra S et al. Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus. 2010 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:20445263
Marreddy RK et al. Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. 2010 PLoS ONE pmid:20436673
Rey B et al. Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. 2010 BMC Physiol. pmid:20426850
Miller MC et al. Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis. 2010 Microbiology (Reading, Engl.) pmid:20413552
Rhee EP et al. Metabolite profiling identifies markers of uremia. 2010 J. Am. Soc. Nephrol. pmid:20378825
Shimshek DR et al. The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy. 2010 PLoS ONE pmid:20368804
Jha SS et al. Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages. 2010 BMC Microbiol. pmid:20359357
el Khoury A and Atoui A Ochratoxin a: general overview and actual molecular status. 2010 Toxins (Basel) pmid:22069596
Hahn MW et al. Limnohabitans australis sp. nov., isolated from a freshwater pond, and emended description of the genus Limnohabitans. 2010 Int. J. Syst. Evol. Microbiol. pmid:20118294
Goncalves S et al. Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples. 2010 BMC Biochem. pmid:20109171
Licht TR et al. Effects of apples and specific apple components on the cecal environment of conventional rats: role of apple pectin. 2010 BMC Microbiol. pmid:20089145
Varela C et al. New structural and functional defects in polyphosphate deficient bacteria: a cellular and proteomic study. 2010 BMC Microbiol. pmid:20067623
Yoshida R Design of self-oscillating gels and application to biomimetic actuators. 2010 Sensors (Basel) pmid:22294901
Li B and Wu LX Poly[[hexa-aqua-(μ(2)-fumarato-κO,O:O,O)bis-(μ(3)-maleato-κO,O:O:O)disamarium(III)] hexa-hydrate]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589236
Silva P et al. catena-Poly[[triaqua-chlorido-μ(3)-malonato-cerium(III)] hemihydrate]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589218
Zeng WL (E)-2,2-Dimethyl-5-(3-phenyl-allyl-idene)-1,3-dioxane-4,6-dione. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589113
Zeng WL et al. 3-(4-Meth-oxy-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589023
Zeng WL 5-(4-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588707
Zeng WL 5-(4-Hy-droxy-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588666
McKinlay JB et al. A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. 2010 BMC Genomics pmid:21118570
Wu J et al. Metabolic changes reveal the development of schistosomiasis in mice. 2010 PLoS Negl Trop Dis pmid:20824219
Dobritsa AA et al. LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. 2010 Plant Physiol. pmid:20442277
Liu SX et al. Dimethyl 2-(2,4,6-trimethoxy-benz-yl)malonate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579465
Liu SX et al. Dimethyl 2-(2-quinolylmeth-yl)malonate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579464
Shahani T et al. Dimethyl 4-(3,4-dimethoxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579441
Wilseck ZM and Laduca RL Poly[[μ(4)-bis-(4-pyridyl-carbon-yl)piperazine-κN:N':O:O']bis-(thio-cyanato-κN)cobalt(II)]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579345
Pochodylo AL and Laduca RL catena-Poly[[diaqua-cadmium(II)]bis-(μ-2,2-dimethyl-butane-dioato-κO,O':O'',O''')[diaqua-cadmium(II)]-μ-1,4-bis-(3-pyridylmeth-yl)piperazine-κN:N]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579341
Win YF et al. Poly[[aquadi-μ(3)-malonato-hexaphenyl-ditin(IV)] acetone solvate]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579332
Chen YM and Xie QF [Malonato(2-)-κO,O']bis-(1,10-phenanthroline-κN,N')zinc(II) penta-hydrate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21522585
Guo ML et al. Poly[tetra-aqua-di-μ(4)-malonato-barium(II)cadmium(II)]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21522548
Guo ML Poly[diaqua-μ(3)-4-nitro-phthalato-copper(II)]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21522547
Guo ML et al. Poly[[μ(2)-aqua-tetraaquadi-μ(3)-malonato-nickel(II)strontium(II)] dihydrate]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21522545
Benedito VA et al. Genomic inventory and transcriptional analysis of Medicago truncatula transporters. 2010 Plant Physiol. pmid:20023147
Demetrius LA et al. Cancer proliferation and therapy: the Warburg effect and quantum metabolism. 2010 Theor Biol Med Model pmid:20085650
Scotti C et al. Cell-cycle inhibition by Helicobacter pylori L-asparaginase. 2010 PLoS ONE pmid:21085483
Luévano-Martínez LA et al. Identification of the mitochondrial carrier that provides Yarrowia lipolytica with a fatty acid-induced and nucleotide-sensitive uncoupling protein-like activity. 2010 Biochim. Biophys. Acta pmid:19766093
Salinero KK et al. Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation. 2009 BMC Genomics pmid:19650930
Karakikes I et al. Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. 2009 PLoS ONE pmid:19649297
Wong HR et al. Identification of pediatric septic shock subclasses based on genome-wide expression profiling. 2009 BMC Med pmid:19624809
Gu J et al. Genomic and systems evolution in Vibrionaceae species. 2009 BMC Genomics pmid:19594870
Vaughan AM et al. Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. 2009 Cell. Microbiol. pmid:19068099
Brown AK et al. Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. 2009 PLoS ONE pmid:19609444
Casale A et al. Sequestration of Alkyltin(IV) compounds in aqueous solution: formation, stability, and empirical relationships for the binding of dimethyltin(IV) cation by N- and O-donor ligands. 2009 Bioinorg Chem Appl pmid:19590597
Rachid S et al. Unusual chemistry in the biosynthesis of the antibiotic chondrochlorens. 2009 Chem. Biol. pmid:19171307
Jørgensen TR et al. Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway. 2009 BMC Genomics pmid:19166577
Tiziani S et al. Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. 2009 PLoS ONE pmid:19158949
Zipse H et al. Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. 2009 J. Am. Chem. Soc. pmid:19128178
Tran QT et al. Chemical genomics of cancer chemopreventive dithiolethiones. 2009 Carcinogenesis pmid:19126641
Xie Z et al. Modules of co-regulated metabolites in turmeric (Curcuma longa) rhizome suggest the existence of biosynthetic modules in plant specialized metabolism. 2009 J. Exp. Bot. pmid:19073964
Burow LC et al. Anaerobic central metabolic pathways active during polyhydroxyalkanoate production in uncultured cluster 1 Defluviicoccus enriched in activated sludge communities. 2009 FEMS Microbiol. Lett. pmid:19622073
Chace DH et al. Quantification of malonylcarnitine in dried blood spots by use of MS/MS varies by stable isotope internal standard composition. 2009 Clin. Chim. Acta pmid:19041298
Hoffman HE et al. Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. 2009 J. Med. Chem. pmid:19791805
Tsubogo T et al. Chiral calcium catalysts with neutral coordinative ligands: enantioselective 1,4-addition reactions of 1,3-dicarbonyl compounds to nitroalkenes. 2009 Angew. Chem. Int. Ed. Engl. pmid:19862785
Hamilton S et al. The transcriptional programme of Salmonella enterica serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms. 2009 BMC Genomics pmid:20003355
Gebhard S et al. The low-affinity phosphate transporter PitA is dispensable for in vitro growth of Mycobacterium smegmatis. 2009 BMC Microbiol. pmid:20003273
Spindler M et al. Coenzyme Q10 effects in neurodegenerative disease. 2009 Neuropsychiatr Dis Treat pmid:19966907
Azuma Y and Ota M An evaluation of minimal cellular functions to sustain a bacterial cell. 2009 BMC Syst Biol pmid:19943949
Tan Y et al. Effects of precursor concentration and acidic sulfate in aqueous glyoxal-OH radical oxidation and implications for secondary organic aerosol. 2009 Environ. Sci. Technol. pmid:19924930
Senoglu M et al. Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve. 2009 J Brachial Plex Peripher Nerve Inj pmid:19939272
Juhnke HD et al. Production, characterization and determination of the real catalytic properties of the putative 'succinate dehydrogenase' from Wolinella succinogenes. 2009 Mol. Microbiol. pmid:19170876