Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Nerve Degeneration D009410 53 associated lipids
Parkinson Disease D010300 53 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Nervous System Diseases D009422 37 associated lipids
Fever D005334 35 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Memory Disorders D008569 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Diarrhea D003967 32 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Karakikes I et al. Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. 2009 PLoS ONE pmid:19649297
Brown AK et al. Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. 2009 PLoS ONE pmid:19609444
Pistollato F et al. Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. 2009 PLoS ONE pmid:19587783
Lallous N et al. The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers. 2011 PLoS ONE pmid:22096602
Oberto J et al. The HU regulon is composed of genes responding to anaerobiosis, acid stress, high osmolarity and SOS induction. 2009 PLoS ONE pmid:19194530
Tiziani S et al. Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. 2009 PLoS ONE pmid:19158949
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Finley LW et al. Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. 2011 PLoS ONE pmid:21858060
Jeong YS et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. 2011 PLoS ONE pmid:21811631
Rogers GW et al. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. 2011 PLoS ONE pmid:21799747
Ruiz M et al. A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. 2012 PLoS ONE pmid:23056435
Egea PF et al. Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. 2008 PLoS ONE pmid:18953414
Eloe EA et al. Going deeper: metagenome of a hadopelagic microbial community. 2011 PLoS ONE pmid:21629664
Lin H et al. The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. 2011 PLoS ONE pmid:21552483
García-Torres I et al. Identification of amino acids that account for long-range interactions in two triosephosphate isomerases from pathogenic trypanosomes. 2011 PLoS ONE pmid:21533154
Rudrappa T et al. Cyanogenic pseudomonads influence multitrophic interactions in the rhizosphere. 2008 PLoS ONE pmid:18446201
Thomas B et al. Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. 2011 PLoS ONE pmid:21304957
Qi M et al. Genome sequence analyses of Pseudomonas savastanoi pv. glycinea and subtractive hybridization-based comparative genomics with nine pseudomonads. 2011 PLoS ONE pmid:21304594
Kubicek J et al. Controlled in meso phase crystallization--a method for the structural investigation of membrane proteins. 2012 PLoS ONE pmid:22536388
Kil DY et al. Age and diet affect gene expression profiles in canine liver tissue. 2010 PLoS ONE pmid:20967283
Shi T et al. cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. 2010 PLoS ONE pmid:20957031
Mailloux RJ et al. The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. 2007 PLoS ONE pmid:17668068
Wise JK et al. Temporal gene expression profiling during rat femoral marrow ablation-induced intramembranous bone regeneration. 2010 PLoS ONE pmid:20957030
Pradhan RK et al. Characterization of membrane potential dependency of mitochondrial Ca2+ uptake by an improved biophysical model of mitochondrial Ca2+ uniporter. 2010 PLoS ONE pmid:20949039
Wu L et al. Comparative metaproteomic analysis on consecutively Rehmannia glutinosa-monocultured rhizosphere soil. 2011 PLoS ONE pmid:21655235
Mochel F et al. Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. 2007 PLoS ONE pmid:17653274
Hanin A et al. Screening of in vivo activated genes in Enterococcus faecalis during insect and mouse infections and growth in urine. 2010 PLoS ONE pmid:20686694
Psychogios N et al. The human serum metabolome. 2011 PLoS ONE pmid:21359215
Granjon T et al. Structure-function relations in oxaloacetate decarboxylase complex. Fluorescence and infrared approaches to monitor oxomalonate and Na(+) binding effect. 2010 PLoS ONE pmid:20543879
Amoêdo ND et al. Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. 2011 PLoS ONE pmid:21789245
Shimshek DR et al. The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy. 2010 PLoS ONE pmid:20368804
Lim S et al. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. 2011 PLoS ONE pmid:21931779
Gonzalvez F et al. Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin. 2010 PLoS ONE pmid:20179769
Zhao JS et al. Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation. 2010 PLoS ONE pmid:20174598
Smejkalová H et al. Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. 2010 PLoS ONE pmid:20957036
Hagemann TL et al. Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival. 2012 PLoS ONE pmid:22693571
Ferramosca A et al. A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats. 2012 PLoS ONE pmid:22685607
Anand K et al. Structural analyses of the Slm1-PH domain demonstrate ligand binding in the non-canonical site. 2012 PLoS ONE pmid:22574179
Tao X et al. Digital gene expression analysis based on integrated de novo transcriptome assembly of sweet potato [Ipomoea batatas (L.) Lam]. 2012 PLoS ONE pmid:22558397
Xiao L et al. Transcriptome of protoplasts reprogrammed into stem cells in Physcomitrella patens. 2012 PLoS ONE pmid:22545152
Scalliet G et al. Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. 2012 PLoS ONE pmid:22536383
Xu XM et al. Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. 2009 PLoS ONE pmid:19865480
Perrot O et al. Quantitative assessment of stereotyped and challenged locomotion after lesion of the striatum: a 3D kinematic study in rats. 2009 PLoS ONE pmid:19859550
Gueguen C et al. Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition. 2014 PLoS ONE pmid:24586272
Trushina E et al. Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. 2012 PLoS ONE pmid:22393443
Tran QM et al. Out of plane distortions of the heme b of Escherichia coli succinate dehydrogenase. 2012 PLoS ONE pmid:22393428
Totir M et al. Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization. 2012 PLoS ONE pmid:22393408
Zuno-Floriano FG et al. Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety. 2012 PLoS ONE pmid:22363586
Fujii T and Albarède F Ab initio calculation of the Zn isotope effect in phosphates, citrates, and malates and applications to plants and soil. 2012 PLoS ONE pmid:22363478
Wang N et al. Changes in soybean global gene expression after application of lipo-chitooligosaccharide from Bradyrhizobium japonicum under sub-optimal temperature. 2012 PLoS ONE pmid:22348109