| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypothyroidism | D007037 | 32 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Teratoma | D013724 | 4 associated lipids |
| Hemoglobinopathies | D006453 | 7 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| PARDEE AB and POTTER VR | Malonate inhibition of oxidations in the Krebs tricarboxylic acid cycle. | 1949 | J. Biol. Chem. | pmid:18112108 |
| GRUBER CM et al. | A toxicologic study of sodium malonate. | 1949 | Arch Int Pharmacodyn Ther | pmid:18152910 |
| LIFSON N and STOLEN JA | Metabolism of C13-carboxyl-labeled malonate by the intact mouse. | 1950 | Proc. Soc. Exp. Biol. Med. | pmid:15440851 |
| LEE JS and LIFSON N | Studies on the conversion of acetate, lactate, and malonate to succinate in the intact rat. | 1951 | J. Biol. Chem. | pmid:14907712 |
| RULON O | The modification of developmental pattern in the sand dollar by malonic acid. | 1951 | Physiol. Zool. | pmid:14807725 |
| POTTER VR and SIMONSON H | Sequential blocking of metabolic pathways in vivo. | 1951 | Proc. Soc. Exp. Biol. Med. | pmid:14816386 |
| LINDSAY JG et al. | C13 isotope effect in the decarboxylation of normal malonic acid. | 1951 | Can J Chem | pmid:14821851 |
| BUSCH H and POTTER VR | Succinate accumulation in vivo following injection of malonate. | 1952 | J. Biol. Chem. | pmid:12999717 |
| BUSCH H and POTTER VR | Studies on tissue metabolism by means of in vivo metabolic blocking technics. I. A survey of changes induced by malonate in tissues of tumor-bearing rats. | 1952 | Cancer Res. | pmid:12978997 |
| THORN MB | Inhibition by malonate of succinic dehydrogenase in heart-muscle preparations. | 1953 | Biochem. J. | pmid:13058948 |
| BUSCH H and POTTER VR | Studies on tissue metabolism by means of in vivo metabolic blocking technics. II. Metabolism of acetate-1-C14 in malonate-treated rats. | 1953 | Cancer Res. | pmid:13042804 |
| THORN MB | Malonate inhibition of succinic dehydrogenase. | 1953 | Biochem. J. | pmid:13037647 |
| WOLFE JB and RITTENBERG SC | Malonate decarboxylation by Pseudomonas fluorescens. III. The rôle of acetyl coenzyme A. | 1954 | J. Biol. Chem. | pmid:13192143 |
| WOLFE JB et al. | Malonate decarboxylation by Pseudomonas fluorescens. II. Magnesium dependency and trapping of active intermediates. | 1954 | J. Biol. Chem. | pmid:13192142 |
| WOLFE JB et al. | Malonate decarboxylation by Pseudomonas fluorescens. I. Observations with dry cells and cell-free preparations. | 1954 | J. Biol. Chem. | pmid:13192141 |
| HAYAISHI O | Enzymatic decarboxylation of malonic acid. | 1955 | J. Biol. Chem. | pmid:14392148 |
| WOLFE JB et al. | Malonate oxidation by dry cells and cell-free extracts of Pseudomonas fluorescens. | 1955 | J. Bacteriol. | pmid:14367265 |
| MOOKERJEA S and SADHU DP | Metabolic depression by arsenite and malonate and cholesterologenesis. | 1955 | Arch. Biochem. Biophys. | pmid:13259694 |
| NAKADA HI et al. | Degradation of malonic acid by rat tissues. | 1957 | J. Biol. Chem. | pmid:13428746 |
| VICKERY HB and PALMER JK | The metabolism of the organic acids of tobacco leaves. XII. Effect of culture of excised leaves in solutions of malonate at pH 4 to pH 7. | 1957 | J. Biol. Chem. | pmid:13416266 |
| ROSTENBERG A and GONZALEZ EL | The inhibition of perspiration by means of the topical application of malonic acid salts. | 1957 | J. Invest. Dermatol. | pmid:13491887 |
| VICKERY HB | The metabolism of the organic acids of tobacco leaves. XVI. Effect of culture of excised leaves in solutions of malonate. | 1959 | J. Biol. Chem. | pmid:13654379 |
| HOSOYA N and KAWADA N | Effect of estradiol, nucleotides and bicarbonate on the metabolism of glucose and malonate. | 1961 | J. Biochem. | pmid:13716089 |
| FAWAZ EN and FAWAZ G | Inhibition of glycolysis in rat skeletal muscle by malonate. | 1962 | Biochem. J. | pmid:13891870 |
| BU'LOCK JD et al. | Malonate as a biosynthetic intermediate in Penicillium urticae. | 1962 | J. Biol. Chem. | pmid:13874181 |
| CRAWFORD MA | The effects of fluoroacetate, malonate and acid-base balance on the renal disposal of citrate. | 1963 | Biochem. J. | pmid:14023730 |
| GOLLAKOTA KG and HALVORSON HO | BIOCHEMICAL CHANGES OCCURRING DURING SPORULATION OF BACILLUS CEREUS T. II. EFFECT OF ESTERS OF ORGANIC ACIDS ON SPORULATION. | 1963 | J. Bacteriol. | pmid:14047234 |
| FRIEDMAN SM et al. | ANTIBIOTIC GLYCOSIDES. V. A COMPARISON OF 2-METHYLMALONATE AND PROPIONATE AS PERCURSORS OF THE C21 BRANCHED CHAIN LACTONE IN ERYTHROMYCIN. | 1964 | J. Biol. Chem. | pmid:14209973 |
| SMITH JA and DELUCA HF | STRUCTURAL CHANGES IN ISOLATED LIVER MITOCHONDRIA OF RATS DURING ESSENTIAL FATTY ACID DEFICIENCY. | 1964 | J. Cell Biol. | pmid:14154491 |
| KOMINEK LA and HALVORSON HO | MODE OF INHIBITION OF SPORULATION OF BACILLUS CEREUS BY ETHYL MALONATE AND ETHYL SUCCINATE. | 1964 | J. Bacteriol. | pmid:14197898 |
| ROBBINS E et al. | DYNAMICS OF ACRIDINE ORANGE-CELL INTERACTION. II. DYE-INDUCED ULTRASTRUCTURAL CHANGES IN MULTIVESICULAR BODIES (ACRIDINE ORANGE PARTICLES). | 1964 | J. Cell Biol. | pmid:14154495 |
| QUAGLIARIELLO E et al. | THE OXIDATION OF GLUTAMATE BY RAT-LIVER MITOCHONDRIA. | 1965 | Biochem. J. | pmid:14342510 |
| BALAZS R | CONTROL OF GLUTAMATE OXIDATION IN BRAIN AND LIVER MITOCHONDRIAL SYSTEMS. | 1965 | Biochem. J. | pmid:14340100 |
| SMITH RM and OSBORNE-WHITE WS | METABOLISM OF PROPIONATE BY SHEEP LIVER. OXIDATION OF PROPIONATE BY HOMOGENATES. | 1965 | Biochem. J. | pmid:14340092 |
| GATENBECK S and BENTLEY R | NAPHTHAQUINONE BIOSYNTHESIS IN MOULDS: THE MECHANISM FOR FORMATION OF JAVANICIN. | 1965 | Biochem. J. | pmid:14348208 |
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| Dey SK et al. | Testicular dehydrogenases in toads after malonate treatment. | 1971 | Acta Histochem. | pmid:4998164 |
| Narayanan N and Eapen J | Effect of malonate, succinate and glucose, in vivo, on the uptake of Cesium-137 by pigeon (Columba livia) muscles. | 1971 | J. Radiat. Res. | pmid:5150020 |
| Jacoby B and Laties GG | Bicarbonate Fixation and Malate Compartmentation in Relation to Salt-induced Stoichiometric Synthesis of Organic Acid. | 1971 | Plant Physiol. | pmid:16657654 |
| Miller RJ and Koeppe DE | The effect of calcium and inhibitors on corn mitochondrial respiration. | 1971 | Plant Physiol. | pmid:16657714 |
| Kupriyanov VV and Saks VA | The effect of succinate, malonate and fumarate on the phosphorylating system of the submitochondrial particles. | 1972 | FEBS Lett. | pmid:4263927 |
| Khurana SC and Gupta CM | Polarography of Cd-malonate-oxalate complex. | 1972 | Talanta | pmid:18961180 |
| McDowell EM | Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. II. Effects of sodium malonate on proximal convoluted tubule. | 1972 | Am. J. Pathol. | pmid:5061663 |
| Dey SK and Deb C | Effect of sodium malonate on ovarian dehydrogenases. A histochemical study. | 1972 | Anat Anz | pmid:5063563 |
| Rafalski A and Raczyñska-Bojanowska K | Synthesis of malonate and methylmalonate and the formation of polyene antibiotics. | 1972 | Acta Biochim. Pol. | pmid:5036391 |
| Sluse FE et al. | Mechanism of the exchanges catalysed by the oxoglutarate translocatory of rat-heart mitochondria. Kinetics of the exchange reactions between 2-oxoglutarate, malate and malonate. | 1972 | Eur. J. Biochem. | pmid:5039837 |
| Dey SK et al. | Pentose phosphate pathway and steroidogenesis in the immature rat ovary after malonate treatment. | 1972 | Acta Endocrinol. | pmid:4677789 |
| Anthony C and Dunstan PM | A novel pathway for bacterial growth on malonate and beta-hydroxybutyrate. | 1972 | Biochem. J. | pmid:4655436 |
| Bergene R and Melo TB | Free radicals in malonic acid: a study of radical conformations at 77K and 295K by the ESR-technique. | 1972 | Biophysik | pmid:4346520 |
| Storey BT and Bahr JT | The Respiratory Chain of Plant Mitochondria: XIV. Ordering of Ubiquinone, Flavoproteins, and Cytochromes in the Respiratory Chain. | 1972 | Plant Physiol. | pmid:16658140 |