Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Alzheimer Disease D000544 76 associated lipids
Teratoma D013724 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Nervous System Diseases D009422 37 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Zíková A et al. The F(0)F(1)-ATP synthase complex contains novel subunits and is essential for procyclic Trypanosoma brucei. 2009 PLoS Pathog. pmid:19436713
Cawthon D et al. Investigation of proton conductance in liver mitochondria of broilers with pulmonary hypertension syndrome. 2004 Poult. Sci. pmid:14979578
Dongmei H et al. Synthesis and analgesic activity of N,N'-dicarbonyltryptamines. 2000 Prep. Biochem. Biotechnol. pmid:10919562
Kagawa Y ATP synthase: from single molecule to human bioenergetics. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20689227
Wada H et al. Why do mitochondria synthesize fatty acids? Evidence for involvement in lipoic acid production. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9037098
Calkins MJ et al. Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15611470
Pain F et al. In vivo quantification of localized neuronal activation and inhibition in the rat brain using a dedicated high temporal-resolution beta +-sensitive microprobe. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12136134
LIFSON N and STOLEN JA Metabolism of C13-carboxyl-labeled malonate by the intact mouse. 1950 Proc. Soc. Exp. Biol. Med. pmid:15440851
Risquez A et al. Effects of malonate administration on renal ammoniagenesis in intact dogs. 1989 Proc. Soc. Exp. Biol. Med. pmid:2602392
POTTER VR and SIMONSON H Sequential blocking of metabolic pathways in vivo. 1951 Proc. Soc. Exp. Biol. Med. pmid:14816386