Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Catalepsy D002375 30 associated lipids
Brain Diseases D001927 27 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Bacterial Infections D001424 21 associated lipids
Hyperglycemia D006943 21 associated lipids
Brain Edema D001929 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Ischemia D007511 18 associated lipids
Neoplasms D009369 13 associated lipids
Abscess D000038 13 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Teratoma D013724 4 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Neoplasms, Muscle Tissue D009379 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Saint-Macary M and Foucher B Binding of malonate to the inner membrane of rat liver mitochondria. 1980 Biochem. Biophys. Res. Commun. pmid:7437047
Garg DN et al. The sero-fermentative-phage types of Salmonella weltevreden. 1980 Zentralbl Bakteriol A pmid:7434993
Koeppen AH et al. Lipid labeling after intracerebral injection of radioactive malonic acid. 1980 J. Neurochem. pmid:7411143
Aizawa M et al. Immobilized mitochondrial electron transport particle for NADH determination. 1980 Biotechnol. Bioeng. pmid:7407338
Kara TC and Patnaik BK Age-related changes in oxygen consumption and the SDH activity of liver homogenate of male garden lizards: effect of malonate and short-term cold stress. 1980 Gerontology pmid:7390165
Tihanyi K et al. Effect of succinate on aminopyrine N-demethylase activity. 1980 Biochim. Biophys. Acta pmid:7388048
Emery T Malonichrome, a new iron chelate from Fusarium roseum. 1980 Biochim. Biophys. Acta pmid:7388041
Konishi K et al. A Halophilic vibrio isolated from a case of chronic cholecystitis. 1981 Microbiol. Immunol. pmid:7334940
Lee KH et al. Antitumor agents. 44. Bis(helenalinyl) esters and related derivatives as novel potent antileukemic agents. 1981 J. Med. Chem. pmid:7328595
Ford WC and Harrison A The role of oxidative phosphorylation in the generation of ATP in human spermatozoa. 1981 J. Reprod. Fertil. pmid:7277330