Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Catalepsy D002375 30 associated lipids
Brain Diseases D001927 27 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Bacterial Infections D001424 21 associated lipids
Hyperglycemia D006943 21 associated lipids
Brain Edema D001929 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Ischemia D007511 18 associated lipids
Neoplasms D009369 13 associated lipids
Abscess D000038 13 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Teratoma D013724 4 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Neoplasms, Muscle Tissue D009379 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Ermayanti TM et al. Stimulation of synthesis and release of swainosonine from transformed roots of Swainsona galegifolia. 1994 Phytochemistry pmid:7764877
Klein BY et al. Analysis of cell-mediated mineralization in culture of bone-derived embryonic cells with neurofibromatosis. 1995 J. Cell. Biochem. pmid:7768987
Kirschner PB et al. Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats. 1995 J. Cereb. Blood Flow Metab. pmid:7790410
Nieva-Gomez D and Konisky J Membrane changes in Escherichia coli induced by colicin Ia and agents known to disrupt energy transduction. 1976 Biochemistry pmid:779829
Oldendorf WH et al. Transient blood-brain barrier passage of polar compounds at low pH. 1994 Am. J. Physiol. pmid:7810722
Brand MD et al. The sum of flux control coefficients in the electron-transport chain of mitochondria. 1994 Eur. J. Biochem. pmid:7813471
Kim YS and Kim EJ A plasmid responsible for malonate assimilation in Pseudomonas fluorescens. 1994 Plasmid pmid:7846146
Ray S et al. Inhibition of electron flow through complex I of the mitochondrial respiratory chain of Ehrlich ascites carcinoma cells by methylglyoxal. 1994 Biochem. J. pmid:7945267
Beal MF et al. Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. 1994 Ann. Neurol. pmid:7998775
Reiss U and Rothstein M Age-related changes in isocitrate lyase from the free living nematode, Turbatrix aceti. 1975 J. Biol. Chem. pmid:803500