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Met Based Drugs |
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Inorg Chem |
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Inorg Chem |
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A novel alpha-helix-liked metallohelicate series and their structural adjustments for the isomorphous substitution. |
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Inorg Chem |
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Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. membranaceus. |
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Exp Brain Res |
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Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. |
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Biochemistry |
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Proteus virulence: involvement of the pore forming alpha-hemolysin (a short review). |
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Role of malonate in chickpeas. |
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Phytochemistry |
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The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies. |
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Physicochemical and crystallographic evidence for polymorphism of the racemic ethyl (2-chloromethyl-2,3-dihydro-5H-oxazolo [3, 2-a]pyrimidin-5-one)-6-carboxylate. |
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J Pharm Sci |
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Identification of active-site residues in Bradyrhizobium japonicum malonyl-coenzyme A synthetase. |
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Synthesis and analgesic activity of N,N'-dicarbonyltryptamines. |
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Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. |
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J Control Release |
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Oxidative stress during energy impairment in mesencephalic cultures is not a downstream consequence of a secondary excitotoxicity. |
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Neuroscience |
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Central administration of methamphetamine synergizes with metabolic inhibition to deplete striatal monoamines. |
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Purification and characterization of Plasmodium falciparum succinate dehydrogenase. |
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Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis. |
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Neuroprotective effects of creatine administration against NMDA and malonate toxicity. |
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Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. |
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Synthesis of new derivatives of 3-benzyl-4-R-delta 2-1,2,4-triazolin-5-one and 3,3'-methylidyne bis(4-R-1,2,4-delta 2-triazolin-5-one). |
2000 May-Jun |
Acta Pol Pharm |
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Solid phase combinatorial synthesis of a library of macro-heterocycles and related acyclic compounds. |
2000 Nov-Dec |
J Comb Chem |
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The Pseudomonas aeruginosa acsA gene, encoding an acetyl-CoA synthetase, is essential for growth on ethanol. |
2001 |
Microbiology (Reading, Engl.) |
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Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. |
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Anal. Biochem. |
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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations. |
2001 |
Biochemistry |
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Anthocyanins from the scarlet flowers of Anemone coronaria. |
2001 |
Phytochemistry |
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Role of corticostriatal and nigrostriatal inputs in malonate-induced striatal toxicity. |
2001 |
Neuroreport |
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Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. |
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Biogenesis of the dicarboxylate carrier (DIC): translocation across the mitochondrial outer membrane and subsequent release from the TOM channel are membrane potential-independent. |
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Tsitologiia |
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Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length. |
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Pattern formation in a tunable medium: the Belousov-Zhabotinsky reaction in an aerosol OT microemulsion. |
2001 |
Phys. Rev. Lett. |
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Advanced solid-state NMR methods for the elucidation of structure and dynamics of molecular, macromolecular, and supramolecular systems. |
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Chem. Rev. |
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N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury. |
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The simplest supramolecular complexes containing pairs of Mo(2)(formamidinate)(3) units linked with various dicarboxylates: preparative methods, structures, and electrochemistry. |
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Inorg Chem |
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2001 |
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A comparison of salts for the crystallization of macromolecules. |
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Protein Sci. |
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Heterologous expression of athermostable manganese peroxidase from Dichomitus squalens in Phanerochaete chrysosporium. |
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Specific inhibition of type II inosine monophosphate dehydrogenase activity of Tmolt4 T cell human leukaemia cells by 3-methoxy and di-benzohydroxamic acids, maleic hydrazide and malonic acids. |
2001 |
J. Pharm. Pharmacol. |
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Remarkably broad substrate tolerance of malonyl-CoA synthetase, an enzyme capable of intracellular synthesis of polyketide precursors. |
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Novel mimics of sialyl Lewis X: design, synthesis and biological activity of a series of 2- and 3-malonate substituted galactoconjugates. |
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Bioorg. Med. Chem. |
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Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures. |
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Geminal dicarboxylates as carbonyl surrogates for asymmetric synthesis. Part I. Asymmetric addition of malonate nucleophiles. |
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Long term adaptation of a microbial population to a permanent metabolic constraint: overcoming thymineless death by experimental evolution of Escherichia coli. |
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Myocardial metabolism of exogenous FDP is consistent with transport by a dicarboxylate transporter. |
2001 |
Am. J. Physiol. Heart Circ. Physiol. |
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Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II. |
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J. Biol. Chem. |
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A third crystal form of Wolinella succinogenes quinol:fumarate reductase reveals domain closure at the site of fumarate reduction. |
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Contributions of the substrate-binding arginine residues to maleate-induced closure of the active site of Escherichia coli aspartate aminotransferase. |
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Inhibition and regulation of rat liver L-threonine dehydrogenase by different fatty acids and their derivatives. |
2001 |
Biochim. Biophys. Acta |
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