Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Nerve Degeneration D009410 53 associated lipids
Fever D005334 35 associated lipids
Catalepsy D002375 30 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Parkinson Disease D010300 53 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Insulin Resistance D007333 99 associated lipids
Memory Disorders D008569 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Neoplasms, Muscle Tissue D009379 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Kumar A et al. Synergistical neuroprotection of rofecoxib and statins against malonic acid induced Huntington's disease like symptoms and related cognitive dysfunction in rats. 2013 Eur. J. Pharmacol. pmid:23562615
MacCrehan WA and White CM Simplified ultrasonically- and microwave-assisted solvent extractions for the determination of ginsenosides in powdered Panax ginseng rhizomes using liquid chromatography with UV absorbance or electrospray mass spectrometric detection. 2013 Anal Bioanal Chem pmid:23564283
Darvas M et al. Molecular dynamics simulations of the water adsorption around malonic acid aerosol models. 2013 Phys Chem Chem Phys pmid:23702947
Zhou S et al. Production of 3-hydroxypropionic acid from glycerol by recombinant Pseudomonas denitrificans. 2013 Biotechnol. Bioeng. pmid:23775313
Salem AA et al. Application of quantitative nuclear magnetic resonance spectroscopy for the determination ofamantadine and acyclovir in plasma and pharmaceutical samples. 2012 Nov-Dec J AOAC Int pmid:23451380
Mahendradas P et al. Unilateral conjunctival ulcer due to Stenotrophomonas maltophilia infection. 2012 Mar-Apr Indian J Ophthalmol pmid:22446910
Jang YJ et al. Tandem three-component reactions of aldehyde, alkyl acrylate, and dialkylmalonate catalyzed by ethyl diphenylphosphine. 2012 Molecules pmid:22446986
Führs H et al. Functional associations between the metabolome and manganese tolerance in Vigna unguiculata. 2012 J. Exp. Bot. pmid:21934118
Yang J et al. One-step hydrothermal synthesis of carboxyl-functionalized upconversion phosphors for bioapplications. 2012 Chemistry pmid:22996059
Ghosh SK et al. Highly enantioselective and recyclable organocatalytic Michael addition of malonates to α,β-unsaturated aldehydes in aqueous media. 2012 Org. Biomol. Chem. pmid:22976596
Bonhomme C et al. 87Sr solid-state NMR as a structurally sensitive tool for the investigation of materials: antiosteoporotic pharmaceuticals and bioactive glasses. 2012 J. Am. Chem. Soc. pmid:22738329
Bauwens M et al. Radioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers. 2012 PLoS ONE pmid:22719886
Callahan DL et al. Elemental and metabolite profiling of nickel hyperaccumulators from New Caledonia. 2012 Phytochemistry pmid:22795763
Chojkier M et al. Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study. 2012 PLoS ONE pmid:22412837
Batur M et al. Correlative analysis of neoplasm patients with phlegm-stasis or abnormal Savda syndrome, based on metabonomics. 2012 J Tradit Chin Med pmid:22594115
Chanumolu SK et al. UniDrug-target: a computational tool to identify unique drug targets in pathogenic bacteria. 2012 PLoS ONE pmid:22431985
Haferkamp I and Schmitz-Esser S The plant mitochondrial carrier family: functional and evolutionary aspects. 2012 Front Plant Sci pmid:22639632
Tomita Y et al. Genome and transcriptome analysis of the food-yeast Candida utilis. 2012 PLoS ONE pmid:22629373
Thein M et al. DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates. 2012 PLoS ONE pmid:22590556
Lapanje K et al. Bis(acetato-κO)bis-[2-(pyridin-2-yl)ethanol-κ(2)N,O]copper(II). 2012 Acta Crystallogr Sect E Struct Rep Online pmid:22590106