Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Alzheimer Disease D000544 76 associated lipids
Teratoma D013724 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Nervous System Diseases D009422 37 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Buyukgebiz B et al. Fatal neonatal malonic aciduria. 1998 J. Inherit. Metab. Dis. pmid:9501274
Williams DM et al. Role of copper in mitochondrial iron metabolism. 1976 Blood pmid:947406
Zalups RK and Barfuss DW Small aliphatic dicarboxylic acids inhibit renal uptake of administered mercury. 1998 Toxicol. Appl. Pharmacol. pmid:9465278
Graf von Roedern E et al. Design and synthesis of malonic acid-based inhibitors of human neutrophil collagenase (MMP8). 1998 J. Med. Chem. pmid:9464365
Willis CL et al. Nutritional aspects of dissimilatory sulfate reduction in the human large intestine. 1997 Curr. Microbiol. pmid:9462959
Matthews RT et al. Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease. 1998 J. Neurosci. pmid:9412496
Sonsalla PK et al. Inhibition of striatal energy metabolism produces cell loss in the ipsilateral substantia nigra. 1997 Brain Res. pmid:9409726
van der Spoel D and Berendsen HJ Determination of proton transfer rate constants using Ab initio, molecular dynamics and density matrix evolution calculations. 1996 Pac Symp Biocomput pmid:9390263
Saris NE On the mechanism of rebounding of calcium in liver mitochondria. 1997 Biol. Chem. pmid:9372185
Korshunov SS et al. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. 1997 FEBS Lett. pmid:9369223