Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Fever D005334 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Nerve Degeneration D009410 53 associated lipids
Parkinson Disease D010300 53 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Alzheimer Disease D000544 76 associated lipids
Brain Ischemia D002545 89 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Salomons GS et al. Clinical, enzymatic and molecular characterization of nine new patients with malonyl-coenzyme A decarboxylase deficiency. 2007 J. Inherit. Metab. Dis. pmid:17186413
Gomez-Lazaro M et al. Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate. 2007 Mol. Pharmacol. pmid:17172466
Saito N et al. 7-Polyacylated delphinidin 3,7-diglucosides from the blue flowers of Leschenaultia cv. Violet Lena. 2007 Phytochemistry pmid:17174991
Zhang D et al. Synthesis of indenes by the transition metal-mediated carboannulation of alkynes. 2007 J. Org. Chem. pmid:17194107
Watts RJ et al. Enhanced stability of hydrogen peroxide in the presence of subsurface solids. 2007 J. Contam. Hydrol. pmid:17196706
Young KC et al. Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex. 2007 Neurobiol. Dis. pmid:17240155
Han C et al. Photo-induced cold vapor generation with low molecular weight alcohol, aldehyde, or carboxylic acid for atomic fluorescence spectrometric determination of mercury. 2007 Anal Bioanal Chem pmid:17216165
Pizzuto R et al. Is there a pyruvate kinase in pig liver mitochondria? 2007 Ital. J. Biochem. pmid:19192625
Turner P et al. Potential and utilization of thermophiles and thermostable enzymes in biorefining. 2007 Microb. Cell Fact. pmid:17359551
Ruangpornvisuti V and Wanno B Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study. 2007 J Mol Model pmid:16738872
Gary-Bobo M et al. Mannose 6-phosphate receptor targeting and its applications in human diseases. 2007 Curr. Med. Chem. pmid:18220730
Bakry R et al. Medicinal applications of fullerenes. 2007 Int J Nanomedicine pmid:18203430
Creaven BS et al. Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenanthroline). 2007 J. Inorg. Biochem. pmid:17555821
Sakurai T et al. Sequencing analysis of 20,000 full-length cDNA clones from cassava reveals lineage specific expansions in gene families related to stress response. 2007 BMC Plant Biol. pmid:18096061
Bruegger D et al. Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions. 2007 Crit Care pmid:18081930
Mailloux RJ et al. The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. 2007 PLoS ONE pmid:17668068
Zara V et al. Biogenesis of yeast dicarboxylate carrier: the carrier signature facilitates translocation across the mitochondrial outer membrane. 2007 J. Cell. Sci. pmid:18032784
Kovermann P et al. The Arabidopsis vacuolar malate channel is a member of the ALMT family. 2007 Plant J. pmid:18005230
Bergholz TM et al. Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium. 2007 BMC Microbiol. pmid:17967175
Storozhevykh TP et al. Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. 2007 BMC Neurosci pmid:17919343
Cao X et al. Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology. 2007 BMC Neurosci pmid:17868476
Lovell TM et al. Identification of a novel mammalian post-translational modification, phosphocholine, on placental secretory polypeptides. 2007 J. Mol. Endocrinol. pmid:17766644
Vindal V et al. GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. 2007 BMC Genomics pmid:17714599
Cerar J et al. Analysis of sample of highly water-soluble Th-symmetric fullerenehexamalonic acid C66(COOH)12 by ion-chromatography and capillary electrophoresis. 2007 J Chromatogr A pmid:17888933
Kim HI and Beauchamp JL Cluster phase chemistry: collisions of vibrationally excited cationic dicarboxylic acid clusters with water molecules initiate dissociation of cluster components. 2007 J Phys Chem A pmid:17569511
Nkuku CA and LeSuer RJ Electrochemistry in deep eutectic solvents. 2007 J Phys Chem B pmid:17973421
Polygalova OO et al. [Wheat root cells functioning under inhibition of I and II complexes of mitochondrial respiratory chain]. 2007 Tsitologiia pmid:17926562
Diener MD et al. (212)Pb@C(60) and its water-soluble derivatives: synthesis, stability, and suitability for radioimmunotherapy. 2007 J. Am. Chem. Soc. pmid:17394315
Mizuno Y et al. Crystal structure of Arabidopsis PII reveals novel structural elements unique to plants. 2007 Biochemistry pmid:17279613
Volonterio A and Zanda M Three-component, one-pot sequential synthesis of N-aryl, N'-alkyl barbiturates. 2007 Org. Lett. pmid:17284045
Neretti N et al. Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation. 2007 BMC Bioinformatics pmid:17430560
Puntel RL et al. Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates. 2007 Life Sci. pmid:17532009
Malvagia S et al. Fatal malonyl CoA decarboxylase deficiency due to maternal uniparental isodisomy of the telomeric end of chromosome 16. 2007 Ann. Hum. Genet. pmid:17535268
Tucker DL et al. Characterization of Escherichia coli MG1655 grown in a low-shear modeled microgravity environment. 2007 BMC Microbiol. pmid:17343762
Schurr A and Payne RS Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. 2007 Neuroscience pmid:17560727
Ravcheev DA et al. Comparative genomic analysis of regulation of anaerobic respiration in ten genomes from three families of gamma-proteobacteria (Enterobacteriaceae, Pasteurellaceae, Vibrionaceae). 2007 BMC Genomics pmid:17313674
Himeno S et al. Simultaneous determination of phosphonate, phosphate, and diphosphate by capillary electrophoresis using in-capillary complexation with Mo(VI). 2007 J Sep Sci pmid:17566343
Schneider S et al. Crystallization and X-ray diffraction analysis of the DNA-remodelling protein DnaD from Bacillus subtilis. 2007 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:17277452
Fan R et al. Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates. 2007 J. Org. Chem. pmid:17585824
Nilwarangkoon S et al. Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway. 2007 J. Pharmacol. Sci. pmid:17220594
Plush SE and Gunnlaugsson T Luminescent sensing of dicarboxylates in water by a bismacrocyclic dinuclear Eu(III) conjugate. 2007 Org. Lett. pmid:17447771
Lockyer AE et al. Biomphalaria glabrata transcriptome: identification of cell-signalling, transcriptional control and immune-related genes from open reading frame expressed sequence tags (ORESTES). 2007 Dev. Comp. Immunol. pmid:17208299
Xie D et al. catena-Poly[[aqua-dipyridine-copper(II)]-μ-fumarato]. 2007 Acta Crystallogr Sect E Struct Rep Online pmid:21200658
Chojnacki H Proton transfer in some periodic molecular systems. 2007 J Mol Model pmid:17479303
Zhang BY et al. Bis(pyrimidine-2-carboxyl-ato-κN,O)copper(II). 2007 Acta Crystallogr Sect E Struct Rep Online pmid:21200639
Karki S et al. Powder X-ray diffraction as an emerging method to structurally characterize organic solids. 2007 Org. Lett. pmid:17629292
Najafpour MM et al. Bis(guanidinium) trans-diaqua-bis(malonato-κO,O')cobaltate(II). 2007 Acta Crystallogr Sect E Struct Rep Online pmid:21200534
Lubkoll J and Wennemers H Mimicry of polyketide synthases--enantioselective 1,4-addition reactions of malonic acid half-thioesters to nitroolefins. 2007 Angew. Chem. Int. Ed. Engl. pmid:17680584
Panee J et al. The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. 2007 Int. J. Biol. Sci. pmid:17657281
Yip SF et al. Room-temperature copper-catalyzed alpha-arylation of malonates. 2007 Org. Lett. pmid:17637034
Koponen IK et al. Thermodynamic properties of malonic, succinic, and glutaric acids: evaporation rates and saturation vapor pressures. 2007 Environ. Sci. Technol. pmid:17612170
Zeevalk GD et al. Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease. 2007 Exp. Neurol. pmid:17049515
Kawatsura M et al. Retention of regiochemistry of monosubstituted allyl acetates in the ruthenium catalysed allylic alkylation with malonate anion. 2007 Chem. Commun. (Camb.) pmid:18217606
Li J et al. Role of Nrf2-dependent ARE-driven antioxidant pathway in neuroprotection. 2007 Methods Mol. Biol. pmid:18309926
Kripal R and Singh DK ESR and optical study of Cu2+ doped calcium malonate dihydrate. 2007 Spectrochim Acta A Mol Biomol Spectrosc pmid:17018262
Deegan C et al. In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)]x2H2O, [Cu(phen)2(mal)]x2H2O and [Mn(phen)2(mal)]x2H2O (malH2=malonic acid) using human cancer cells. 2007 Cancer Lett. pmid:16740357
Wang GW and Li FB Radical reactions of [60]fullerene mediated by manganese(III) acetate dihydrate. 2007 Apr-May J Nanosci Nanotechnol pmid:17450885
Zheng GH et al. Feasibility of 2,4,6-trichlorophenol and malonic acid as metabolic uncoupler for sludge reduction in the sequence batch reactor for treating organic wastewater. 2008 Appl. Biochem. Biotechnol. pmid:18456942
Vanag VK and Epstein IR Design and control of patterns in reaction-diffusion systems. 2008 Chaos pmid:18601509
Hara Y and Yoshida R Self-oscillating polymer fueled by organic acid. 2008 J Phys Chem B pmid:18588335
Jackson CJ et al. Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. 2008 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:18678932
Vanag VK et al. Cross-diffusion in a water-in-oil microemulsion loaded with malonic acid or ferroin. Taylor dispersion method for four-component systems. 2008 J Phys Chem B pmid:18610956
Mulholland NP et al. A concise and straightforward total synthesis of (+/-)-salinosporamide A, based on a biosynthesis model. 2008 Org. Biomol. Chem. pmid:18633536
Sonawane ND et al. Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides. 2008 Chem. Biol. pmid:18635008
Laus MN et al. Plant inner membrane anion channel (PIMAC) function in plant mitochondria. 2008 Plant Cell Physiol. pmid:18511459
Crea F et al. Sequestering ability of polycarboxylic ligands towards dioxouranium(VI). 2008 Talanta pmid:18585146
Tatsuzawa F et al. Triacylated cyanidin 3-(3X-glucosylsambubioside)-5-glucosides from the flowers of Malcolmia maritima. 2008 Phytochemistry pmid:17928016
Lockyer AE et al. Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni. 2008 BMC Genomics pmid:19114004
Li Y et al. Metabolic pathway alignment between species using a comprehensive and flexible similarity measure. 2008 BMC Syst Biol pmid:19108747
Calura E et al. Meta-analysis of expression signatures of muscle atrophy: gene interaction networks in early and late stages. 2008 BMC Genomics pmid:19108710
Naik PR et al. Assessment of genetic and functional diversity of phosphate solubilizing fluorescent pseudomonads isolated from rhizospheric soil. 2008 BMC Microbiol. pmid:19099598
Johnson JA et al. The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. 2008 Ann. N. Y. Acad. Sci. pmid:19076431
Buchman VL and Ninkina N Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze? 2008 Neurotox Res pmid:19073436
Gaur M et al. MFS transportome of the human pathogenic yeast Candida albicans. 2008 BMC Genomics pmid:19055746
Lopanik NB et al. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. 2008 Chem. Biol. pmid:19022178
Berenstein I and Muñuzuri AP Coexistence of Eckhaus instability in forced zigzag Turing patterns. 2008 J Chem Phys pmid:19044970
Chandra R et al. Isolation and characterization of bacterial strains Paenibacillus sp. and Bacillus sp. for kraft lignin decolorization from pulp paper mill waste. 2008 J. Gen. Appl. Microbiol. pmid:19164883
Saito N et al. Tetra-acylated cyanidin 3-sophoroside-5-glucosides from the flowers of Iberis umbellata L. (Cruciferae). 2008 Phytochemistry pmid:18514755
Brazier-Hicks M et al. Catabolism of glutathione conjugates in Arabidopsis thaliana. Role in metabolic reactivation of the herbicide safener fenclorim. 2008 J. Biol. Chem. pmid:18522943
Martin CL et al. Total synthesis of (+/-)-actinophyllic acid. 2008 J. Am. Chem. Soc. pmid:18491907
Jang YH et al. The rate of Salmonella spp. infection in zoo animals at Seoul Grand Park, Korea. 2008 J. Vet. Sci. pmid:18487939
Liu W et al. Preparation, characterization and in vitro anticancer activity of platinum(II) complexes with N-Cyclohexyl-1,3-propanediamine as the carrier. 2008 Chem. Pharm. Bull. pmid:18451553
Vasquez-Robinet C et al. Physiological and molecular adaptations to drought in Andean potato genotypes. 2008 J. Exp. Bot. pmid:18535297
Rudrappa T et al. Cyanogenic pseudomonads influence multitrophic interactions in the rhizosphere. 2008 PLoS ONE pmid:18446201
Qin JH et al. 1,3-Di-4-pyrid-ylpropane-2-hydroxy-benzene-1,4-dicarboxylic acid (1/2). 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581368
Liu Y et al. catena-Poly[[aqua-(2,2'-bipyridyl)cobalt(II)]-μ-5-nitro-isophthalato]. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581202
Farnum GA and Laduca RL Bis(dimethyl-malonato-κO,O')bis-[4-(4-pyridylamino-κN)pyridinium]nickel(II) hexa-hydrate. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581200
Hittle JL and Laduca RL Poly[di-μ(3)-chlorido-[μ(2)-(3-pyrid-yl)(4-pyrid-yl)methanone-κN:N']dicopper(I)]. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581196
Pavlová A et al. Bis(2,2'-bipyridine-κN,N')(maleato-κO,O)nickel(II) 7.34-hydrate. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581151
Hao L and Liu X catena-Poly[[aqua-(2,2'-bipyridine-κN,N')copper(II)]-μ-5-nitro-isophthalato-κO,O:O]. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581121
Hao L and Liu X Triaqua-(2,2'-bipyridine-κN,N')(5-nitro-isophthalato-κO)zinc(II) monohydrate. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581119
Xie HZ et al. μ-α-Methyl-glutarato-bis-{aqua-[bis-(2-pyridylcarbon-yl)aminato]copper(II)} trihydrate. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21580907
Farnum GA and Laduca RL Poly[[diaqua-bis(μ(3)-maleato-κO:O,O:O)dicopper(II)] trihydrate]. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21203054
Hao L et al. catena-Poly[[aqua-{4-[N'-(2,4-dioxo-3-pentyl-idene)-hydrazino]-benzoato}-copper(II)]-μ-acetato]. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21202784
Hao L et al. Tetra-aqua-bis[(1-carboxyl-atomethyl-1,3-benzimidazol-3-ium-3-yl)acetato-κO]palladium(II) dihydrate. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21202762
Chandrasekar S et al. Structure of the chloroplast signal recognition particle (SRP) receptor: domain arrangement modulates SRP-receptor interaction. 2008 J. Mol. Biol. pmid:18035371
Issabayeva G et al. Continuous adsorption of lead ions in a column packed with palm shell activated carbon. 2008 J. Hazard. Mater. pmid:18179867
Parker N et al. Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria. 2008 Biochem. J. pmid:18251717
Mirandola SR et al. Methylmalonate inhibits succinate-supported oxygen consumption by interfering with mitochondrial succinate uptake. 2008 J. Inherit. Metab. Dis. pmid:18213522
Takács M et al. Formate hydrogenlyase in the hyperthermophilic archaeon, Thermococcus litoralis. 2008 BMC Microbiol. pmid:18522724