| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rong T | 2,4,6-Trimethyl-anilinium 2-carb-oxy-ethano-ate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22090968 |
| Zeng WL | 5,5'-[(2,4-Dichloro-phen-yl)methyl-ene]bis-(2,2-dimethyl-1,3-dioxane-4,6-dione). | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22090945 |
| Feng LP and Zhao L | 2-Amino-anilinium 2-carb-oxy-acetate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22090933 |
| Chen H et al. | Malonyl-CoA synthetase, encoded by ACYL ACTIVATING ENZYME13, is essential for growth and development of Arabidopsis. | 2011 | Plant Cell | pmid:21642549 |
| Kotova EA et al. | Selective permeabilization of lipid membranes by photodynamic action via formation of hydrophobic defects or pre-pores. | 2011 | Biochim. Biophys. Acta | pmid:21663731 |
| Funakoshi T et al. | Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine. | 2011 | Toxicol In Vitro | pmid:21664962 |
| Jose DA et al. | Allosteric Pâ•O-based receptors for dicarboxylic acids. | 2011 | Org. Lett. | pmid:21667961 |
| Finley LW et al. | Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. | 2011 | PLoS ONE | pmid:21858060 |
| Lau SK et al. | Transport genes and chemotaxis in Laribacter hongkongensis: a genome-wide analysis. | 2011 | Cell Biosci | pmid:21849034 |
| Bian W et al. | The intermediate products in the degradation of 4-chlorophenol by pulsed high voltage discharge in water. | 2011 | J. Hazard. Mater. | pmid:21802204 |
| Milan M et al. | Transcriptome sequencing and microarray development for the Manila clam, Ruditapes philippinarum: genomic tools for environmental monitoring. | 2011 | BMC Genomics | pmid:21569398 |
| Kim SH et al. | Ameliorating effects of Mango (Mangifera indica L.) fruit on plasma ethanol level in a mouse model assessed with H-NMR based metabolic profiling. | 2011 | J Clin Biochem Nutr | pmid:21562641 |
| Lin H et al. | The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. | 2011 | PLoS ONE | pmid:21552483 |
| Thomas B et al. | Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. | 2011 | PLoS ONE | pmid:21304957 |
| Whitaker-Menezes D et al. | Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. | 2011 | Cell Cycle | pmid:22134189 |
| Alfares A et al. | Combined malonic and methylmalonic aciduria: exome sequencing reveals mutations in the ACSF3 gene in patients with a non-classic phenotype. | 2011 | J. Med. Genet. | pmid:21785126 |
| Witkowski A et al. | Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis. | 2011 | J. Biol. Chem. | pmid:21846720 |
| Araújo WL et al. | Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture. | 2011 | Plant Cell | pmid:21307286 |
| Kaufhold M et al. | Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3. | 2011 | Am. J. Physiol. Renal Physiol. | pmid:21865262 |
| Malik G et al. | Aziridines from intramolecular alkene aziridination of sulfamates: reactivity toward carbon nucleophiles. application to the synthesis of spisulosine and its fluoro analogue. | 2011 | J. Org. Chem. | pmid:21812488 |