Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Mammary Neoplasms, Experimental D008325 67 associated lipids
Memory Disorders D008569 33 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Neoplasms D009369 13 associated lipids
Neoplasms, Muscle Tissue D009379 2 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Parkinson Disease D010300 53 associated lipids
Teratoma D013724 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Armson A et al. The effect of electron transport (ET) inhibitors and thiabendazole on the fumarate reductase (FR) and succinate dehydrogenase (SDH) of Strongyloides ratti infective (L3) larvae. 1995 Int. J. Parasitol. pmid:7622334
Raginskaia VP [Nomenclature of the S. coli (E. coli) No. 2624/36 and 5396/38 strains]. 1975 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:766529
O'Donnell M et al. Evidence from affinity precipitation that glutamate analogues are bound in a folded conformation to glutamate dehydrogenase. 1995 Biochem. Soc. Trans. pmid:7672393
Davolio C and Greenamyre JT Selective vulnerability of the CA1 region of hippocampus to the indirect excitotoxic effects of malonic acid. 1995 Neurosci. Lett. pmid:7675303
Klein BY et al. Selection of malonate-resistant stromal cell-derived osteoprogenitor cells in vitro. 1993 J. Cell. Biochem. pmid:7680046
Beal MF et al. Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate. 1993 J. Neurochem. pmid:7689641
Byun HS and Kim YS Assays for malonate decarboxylase. 1994 Anal. Biochem. pmid:7695096
Davydov VV et al. [Effect of malonate on various aspects of hepatic metabolism]. 1994 Oct-Dec Patol Fiziol Eksp Ter pmid:7700705
Schuster H et al. Substrate and product binding sites of yeast fatty acid synthase. Stoichiometry and binding kinetics of wild-type and in vitro mutated enzymes. 1995 Eur. J. Biochem. pmid:7705357
Dehning I and Schink B Anaerobic degradation of malonate via malonyl-CoA by Sporomusa malonica, Klebsiella oxytoca, and Rhodobacter capsulatus. 1994 Antonie Van Leeuwenhoek pmid:7710283