| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypothyroidism | D007037 | 32 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Hemorrhagic Fever with Renal Syndrome | D006480 | 3 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hemoglobinopathies | D006453 | 7 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gomez-Lazaro M et al. | Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate. | 2007 | Mol. Pharmacol. | pmid:17172466 |
| Saito N et al. | 7-Polyacylated delphinidin 3,7-diglucosides from the blue flowers of Leschenaultia cv. Violet Lena. | 2007 | Phytochemistry | pmid:17174991 |
| Zhang D et al. | Synthesis of indenes by the transition metal-mediated carboannulation of alkynes. | 2007 | J. Org. Chem. | pmid:17194107 |
| Watts RJ et al. | Enhanced stability of hydrogen peroxide in the presence of subsurface solids. | 2007 | J. Contam. Hydrol. | pmid:17196706 |
| Young KC et al. | Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex. | 2007 | Neurobiol. Dis. | pmid:17240155 |
| Aliverdieva DA et al. | Topography of the active site of the Saccharomyces cerevisiae plasmalemmal dicarboxylate transporter studied using lipophilic derivatives of its substrates. | 2007 | Biochemistry Mosc. | pmid:17447879 |
| Pizzuto R et al. | Is there a pyruvate kinase in pig liver mitochondria? | 2007 | Ital. J. Biochem. | pmid:19192625 |
| Slimestad R et al. | Onions: a source of unique dietary flavonoids. | 2007 | J. Agric. Food Chem. | pmid:17997520 |
| Turner P et al. | Potential and utilization of thermophiles and thermostable enzymes in biorefining. | 2007 | Microb. Cell Fact. | pmid:17359551 |
| Ruangpornvisuti V and Wanno B | Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study. | 2007 | J Mol Model | pmid:16738872 |
| Gary-Bobo M et al. | Mannose 6-phosphate receptor targeting and its applications in human diseases. | 2007 | Curr. Med. Chem. | pmid:18220730 |
| Bakry R et al. | Medicinal applications of fullerenes. | 2007 | Int J Nanomedicine | pmid:18203430 |
| Creaven BS et al. | Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenanthroline). | 2007 | J. Inorg. Biochem. | pmid:17555821 |
| Mailloux RJ et al. | The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. | 2007 | PLoS ONE | pmid:17668068 |
| Kovermann P et al. | The Arabidopsis vacuolar malate channel is a member of the ALMT family. | 2007 | Plant J. | pmid:18005230 |
| Bergholz TM et al. | Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium. | 2007 | BMC Microbiol. | pmid:17967175 |
| Storozhevykh TP et al. | Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. | 2007 | BMC Neurosci | pmid:17919343 |
| Cao X et al. | Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology. | 2007 | BMC Neurosci | pmid:17868476 |
| Lovell TM et al. | Identification of a novel mammalian post-translational modification, phosphocholine, on placental secretory polypeptides. | 2007 | J. Mol. Endocrinol. | pmid:17766644 |
| Vindal V et al. | GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. | 2007 | BMC Genomics | pmid:17714599 |
| Stockwell PB | Abstracts of papers presented at the 2007 pittsburgh conference. | 2007 | J Autom Methods Manag Chem | pmid:18528514 |
| Dutertre S et al. | AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. | 2007 | EMBO J. | pmid:17660751 |
| Mochel F et al. | Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. | 2007 | PLoS ONE | pmid:17653274 |
| Pohl T et al. | Effects of the deletion of the Escherichia coli frataxin homologue CyaY on the respiratory NADH:ubiquinone oxidoreductase. | 2007 | BMC Biochem. | pmid:17650323 |
| Cerar J et al. | Analysis of sample of highly water-soluble Th-symmetric fullerenehexamalonic acid C66(COOH)12 by ion-chromatography and capillary electrophoresis. | 2007 | J Chromatogr A | pmid:17888933 |
| Deguchi Y et al. | Transcriptome profiling of Lotus japonicus roots during arbuscular mycorrhiza development and comparison with that of nodulation. | 2007 | DNA Res. | pmid:17634281 |
| Carbone I et al. | Gene duplication, modularity and adaptation in the evolution of the aflatoxin gene cluster. | 2007 | BMC Evol. Biol. | pmid:17620135 |
| Kim HI and Beauchamp JL | Cluster phase chemistry: collisions of vibrationally excited cationic dicarboxylic acid clusters with water molecules initiate dissociation of cluster components. | 2007 | J Phys Chem A | pmid:17569511 |
| Schwartz JM et al. | Observing metabolic functions at the genome scale. | 2007 | Genome Biol. | pmid:17594483 |
| Chiu KP et al. | Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. | 2007 | BMC Cancer | pmid:17594473 |
| Ostrow JD and Mukerjee P | Revalidation and rationale for high pKa values of unconjugated bilirubin. | 2007 | BMC Biochem. | pmid:17475001 |
| Iversen C et al. | The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cronobacter dublinensis sp. nov. and Cronobacter genomospecies 1. | 2007 | BMC Evol. Biol. | pmid:17439656 |
| Neretti N et al. | Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation. | 2007 | BMC Bioinformatics | pmid:17430560 |
| Himeno S et al. | Simultaneous determination of phosphonate, phosphate, and diphosphate by capillary electrophoresis using in-capillary complexation with Mo(VI). | 2007 | J Sep Sci | pmid:17566343 |
| Fan R et al. | Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates. | 2007 | J. Org. Chem. | pmid:17585824 |
| Plush SE and Gunnlaugsson T | Luminescent sensing of dicarboxylates in water by a bismacrocyclic dinuclear Eu(III) conjugate. | 2007 | Org. Lett. | pmid:17447771 |
| Chojnacki H | Proton transfer in some periodic molecular systems. | 2007 | J Mol Model | pmid:17479303 |
| Karki S et al. | Powder X-ray diffraction as an emerging method to structurally characterize organic solids. | 2007 | Org. Lett. | pmid:17629292 |
| Najafpour MM et al. | Bis(guanidinium) trans-diaqua-bis(malonato-κO,O')cobaltate(II). | 2007 | Acta Crystallogr Sect E Struct Rep Online | pmid:21200534 |
| Lubkoll J and Wennemers H | Mimicry of polyketide synthases--enantioselective 1,4-addition reactions of malonic acid half-thioesters to nitroolefins. | 2007 | Angew. Chem. Int. Ed. Engl. | pmid:17680584 |
| Ghosh AK et al. | Syntheses, crystal structures, and magnetic properties of metal-organic hybrid materials of Cu(II): effect of a long chain dicarboxylate backbone, and counteranion in their structural diversity. | 2007 | Inorg Chem | pmid:17373784 |
| Panee J et al. | The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. | 2007 | Int. J. Biol. Sci. | pmid:17657281 |
| Yip SF et al. | Room-temperature copper-catalyzed alpha-arylation of malonates. | 2007 | Org. Lett. | pmid:17637034 |
| Koponen IK et al. | Thermodynamic properties of malonic, succinic, and glutaric acids: evaporation rates and saturation vapor pressures. | 2007 | Environ. Sci. Technol. | pmid:17612170 |
| Fortner KC and Shair MD | Stereoelectronic effects dictate mechanistic dichotomy between Cu(II)-catalyzed and enzyme-catalyzed reactions of malonic acid half thioesters. | 2007 | J. Am. Chem. Soc. | pmid:17263375 |
| Huber SG et al. | Carbon suboxide, a highly reactive intermediate from the abiotic degradation of aromatic compounds in soil. | 2007 | Environ. Sci. Technol. | pmid:18075091 |
| Shen J et al. | Ternary phase diagram for the Belousov-Zhabotinsky reaction-induced mechanical oscillation of intelligent PNIPAM colloids. | 2007 | J Phys Chem A | pmid:17994710 |
| Augustine JK et al. | gem-Dibromomethylarenes: a convenient substitute for noncommercial aldehydes in the knoevenagel-doebner reaction for the synthesis of alpha,beta-unsaturated carboxylic acids. | 2007 | J. Org. Chem. | pmid:17999533 |
| Zeevalk GD et al. | Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease. | 2007 | Exp. Neurol. | pmid:17049515 |
| Lombardi A et al. | Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria. | 2007 | FEBS Lett. | pmid:18054334 |
| Riipinen I et al. | Adipic and malonic acid aqueous solutions: surface tensions and saturation vapor pressures. | 2007 | J Phys Chem A | pmid:18044850 |
| Kawatsura M et al. | Retention of regiochemistry of monosubstituted allyl acetates in the ruthenium catalysed allylic alkylation with malonate anion. | 2007 | Chem. Commun. (Camb.) | pmid:18217606 |
| Kripal R and Singh DK | ESR and optical study of Cu2+ doped calcium malonate dihydrate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17018262 |
| Moy LY et al. | Mitochondrial stress-induced dopamine efflux and neuronal damage by malonate involves the dopamine transporter. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17090704 |
| Gao J et al. | Determination of 1-naphthylamine by using oscillating chemical reaction. | 2007 | J. Hazard. Mater. | pmid:17097225 |
| Deegan C et al. | In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)]x2H2O, [Cu(phen)2(mal)]x2H2O and [Mn(phen)2(mal)]x2H2O (malH2=malonic acid) using human cancer cells. | 2007 | Cancer Lett. | pmid:16740357 |
| Wang GW and Li FB | Radical reactions of [60]fullerene mediated by manganese(III) acetate dihydrate. | 2007 Apr-May | J Nanosci Nanotechnol | pmid:17450885 |
| Okano H et al. | The Influence of a gradient static magnetic field on an unstirred Belousov-Zhabotinsky reaction. | 2008 | Bioelectromagnetics | pmid:18512693 |
| Volonterio A and Zanda M | Multicomponent, one-pot sequential synthesis of 1,3,5- and 1,3,5,5-substituted barbiturates. | 2008 | J. Org. Chem. | pmid:18754580 |
| Kachlicki P et al. | Evaluation of glycosylation and malonylation patterns in flavonoid glycosides during LC/MS/MS metabolite profiling. | 2008 | J Mass Spectrom | pmid:18074333 |
| Yang L and Yu LE | Measurements of oxalic acid, oxalates, malonic acid, and malonates in atmospheric particulates. | 2008 | Environ. Sci. Technol. | pmid:19174903 |
| Blagojević SM et al. | Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions. | 2008 | Phys Chem Chem Phys | pmid:18989478 |
| Sechi M et al. | Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors. | 2008 | Molecules | pmid:18830166 |
| Chisholm MH | Mixed valence complexes involving MM quadruple bonds (M=Mo or W). | 2008 | Philos Trans A Math Phys Eng Sci | pmid:17846014 |
| Hayashimoto N et al. | Study of a Bordetella hinzii isolate from a laboratory mouse. | 2008 | Comp. Med. | pmid:19004369 |
| Egea PF et al. | Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. | 2008 | PLoS ONE | pmid:18953414 |
| Kuwabara M et al. | Regulation of cell survival and death signals induced by oxidative stress. | 2008 | J Clin Biochem Nutr | pmid:18818753 |
| Nemoto T | Transition metal-catalyzed asymmetric reactions using P-chirogenic diaminophosphine oxides: DIAPHOXs. | 2008 | Chem. Pharm. Bull. | pmid:18758091 |
| Jung KH et al. | Identification and functional analysis of light-responsive unique genes and gene family members in rice. | 2008 | PLoS Genet. | pmid:18725934 |
| Palaniappan N et al. | cis-Delta(2,3)-double bond of phoslactomycins is generated by a post-PKS tailoring enzyme. | 2008 | J. Am. Chem. Soc. | pmid:18714992 |
| Rosca MG et al. | Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. | 2008 | Cardiovasc. Res. | pmid:18710878 |
| Hu TC et al. | High-molecular-weight polymers for protein crystallization: poly-gamma-glutamic acid-based precipitants. | 2008 | Acta Crystallogr. D Biol. Crystallogr. | pmid:18703844 |
| Hashimoto T et al. | Evidence for the mitochondrial lactate oxidation complex in rat neurons: demonstration of an essential component of brain lactate shuttles. | 2008 | PLoS ONE | pmid:18698340 |
| De M and Rotello VM | Synthetic "chaperones": nanoparticle-mediated refolding of thermally denatured proteins. | 2008 | Chem. Commun. (Camb.) | pmid:18654694 |
| Buck M | Direct infection and replication of naturally occurring hepatitis C virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures. | 2008 | PLoS ONE | pmid:18628977 |
| Puntel GO et al. | Antioxidant properties of oxime 3-(phenylhydrazono) butan-2-one. | 2008 | Arch. Toxicol. | pmid:18504554 |
| Kuo CJ et al. | Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. | 2008 | J. Biomed. Biotechnol. | pmid:18382620 |
| Zhong Q et al. | Hepatic mitochondrial transport of glutathione: studies in isolated rat liver mitochondria and H4IIE rat hepatoma cells. | 2008 | Arch. Biochem. Biophys. | pmid:18374655 |
| Nagaraj SH et al. | In silico analysis of expressed sequence tags from Trichostrongylus vitrinus (Nematoda): comparison of the automated ESTExplorer workflow platform with conventional database searches. | 2008 | BMC Bioinformatics | pmid:18315841 |
| Kim J et al. | Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. | 2008 | PLoS ONE | pmid:18335064 |
| Boily G et al. | SirT1 regulates energy metabolism and response to caloric restriction in mice. | 2008 | PLoS ONE | pmid:18335035 |
| Dholwani KK et al. | A review on plant-derived natural products and their analogs with anti-tumor activity. | 2008 | Indian J Pharmacol | pmid:21279166 |
| Rakhimova E et al. | Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection. | 2008 | PLoS ONE | pmid:18301762 |
| Amo T et al. | Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. | 2008 | Gene | pmid:18280061 |
| Schrader M and Fahimi HD | The peroxisome: still a mysterious organelle. | 2008 | Histochem. Cell Biol. | pmid:18274771 |
| Iijima Y et al. | Metabolite annotations based on the integration of mass spectral information. | 2008 | Plant J. | pmid:18266924 |
| Orgel LE | The implausibility of metabolic cycles on the prebiotic Earth. | 2008 | PLoS Biol. | pmid:18215113 |
| Wang GW et al. | Dimethyl 2,2-bis-(2-cyano-ethyl)malonate. | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21202343 |
| Chakkaravarthi G et al. | 9-Meth-oxy-5-phenyl-sulfonyl-5H-benzo[b]carbazole. | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21201699 |
| Zobrist B et al. | Heterogeneous ice nucleation in aqueous solutions: the role of water activity. | 2008 | J Phys Chem A | pmid:18363389 |
| Chakkaravarthi G et al. | 7,9-Dimethyl-5-phenyl-sulfonyl-5H-benzo[b]carbazole. | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21201660 |
| Maah MJ et al. | Hexa-μ(2)-acetato-κO:O'-μ(3)-oxido-tris-[aqua-chromium(III)] nitrate acetic acid solvate. | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21201047 |
| Frunzke J et al. | Co-ordinated regulation of gluconate catabolism and glucose uptake in Corynebacterium glutamicum by two functionally equivalent transcriptional regulators, GntR1 and GntR2. | 2008 | Mol. Microbiol. | pmid:18047570 |
| Freilich S et al. | Metabolic innovations towards the human lineage. | 2008 | BMC Evol. Biol. | pmid:18782449 |
| Arizaga GG et al. | Chemical modification of zinc hydroxide nitrate and Zn-Al-layered double hydroxide with dicarboxylic acids. | 2008 | J Colloid Interface Sci | pmid:18243238 |
| Yi C et al. | An efficient and facile synthesis of highly substituted 2,6-dicyanoanilines. | 2008 | J. Org. Chem. | pmid:18341285 |
| Hynes PS et al. | Organocatalytic asymmetric total synthesis of (R)-rolipram and formal synthesis of (3S,4R)-paroxetine. | 2008 | Org. Lett. | pmid:18324820 |
| Rocha MA et al. | Na(+)/H(+) exchanger inhibition modifies dopamine neurotransmission during normal and metabolic stress conditions. | 2008 | J. Neurochem. | pmid:18363831 |
| Marobbio CM et al. | alpha-Isopropylmalate, a leucine biosynthesis intermediate in yeast, is transported by the mitochondrial oxalacetate carrier. | 2008 | J. Biol. Chem. | pmid:18682385 |
| Parker N et al. | Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential. | 2008 | Biosci. Rep. | pmid:18384278 |