| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Neurofibromatosis 1 | D009456 | 4 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:15157076 | ||||
| pmid:15157075 | ||||
| Perez J and Jeffries TW | Roles of manganese and organic acid chelators in regulating lignin degradation and biosynthesis of peroxidases by Phanerochaete chrysosporium. | 1992 | Appl. Environ. Microbiol. | pmid:1514788 |
| pmid:15144199 | ||||
| Wu Q et al. | LC/UV/ESI-MS analysis of isoflavones in Edamame and Tofu soybeans. | 2004 | J. Agric. Food Chem. | pmid:15137811 |
| Fleming I and Ramarao C | Decarboxylative elimination of enol triflates as a general synthesis of acetylenes. | 2004 | Org. Biomol. Chem. | pmid:15136807 |
| pmid:15135911 | ||||
| pmid:15130601 | ||||
| pmid:15124099 | ||||
| pmid:15120856 | ||||
| pmid:15120273 | ||||
| Maragos WF et al. | Striatal damage and oxidative stress induced by the mitochondrial toxin malonate are reduced in clorgyline-treated rats and MAO-A deficient mice. | 2004 | Neurochem. Res. | pmid:15098936 |
| Baud S et al. | gurke and pasticcino3 mutants affected in embryo development are impaired in acetyl-CoA carboxylase. | 2004 | EMBO Rep. | pmid:15088065 |
| pmid:15074940 | ||||
| pmid:15069502 | ||||
| Zhang YQ and Keller NP | Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans. | 2004 | Mol. Microbiol. | pmid:15066039 |
| pmid:15063527 | ||||
| pmid:15051173 | ||||
| Asanuma T et al. | Protection against malonate-induced ischemic brain injury in rat by a cell-permeable peptidic c-Jun N-terminal kinase inhibitor, (L)-HIV-TAT48-57-PP-JBD20, observed by the apparent diffusion coefficient mapping magnetic resonance imaging method. | 2004 | Neurosci. Lett. | pmid:15050711 |
| Kucera LS et al. | Synthesis and evaluation of a novel synthetic phosphocholine lipid-AZT conjugate that double-targets wild-type and drug resistant variants of HIV. | 2004 | Nucleosides Nucleotides Nucleic Acids | pmid:15043162 |
| Ekaratanawong S et al. | Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. | 2004 | J. Pharmacol. Sci. | pmid:15037815 |
| pmid:15037207 | ||||
| pmid:15022215 | ||||
| Klivenyi P et al. | Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. | 2004 | J. Neurochem. | pmid:15009635 |
| pmid:15004362 | ||||
| Jeong J et al. | A nodule-specific dicarboxylate transporter from alder is a member of the peptide transporter family. | 2004 | Plant Physiol. | pmid:15001700 |
| Taniguchi Y et al. | Differentiation of dicarboxylate transporters in mesophyll and bundle sheath chloroplasts of maize. | 2004 | Plant Cell Physiol. | pmid:14988489 |
| Kiss C et al. | Cortical spreading depression augments kynurenate levels and reduces malonate toxicity in the rat cortex. | 2004 | Brain Res. | pmid:14988042 |
| pmid:14982455 | ||||
| Cawthon D et al. | Investigation of proton conductance in liver mitochondria of broilers with pulmonary hypertension syndrome. | 2004 | Poult. Sci. | pmid:14979578 |
| pmid:14973627 | ||||
| Murphy RC and Messer A | A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease. | 2004 | Brain Res. Mol. Brain Res. | pmid:14969746 |
| Hopwood DA | Cracking the polyketide code. | 2004 | PLoS Biol. | pmid:14966534 |
| pmid:14924659 | ||||
| LEE JS and LIFSON N | Studies on the conversion of acetate, lactate, and malonate to succinate in the intact rat. | 1951 | J. Biol. Chem. | pmid:14907712 |
| pmid:14904052 | ||||
| Davydov VV et al. | [The effect of malonate on lipid biosynthesis in the liver]. | 1992 Nov-Dec | Ukr. Biokhim. Zh. | pmid:1488816 |
| Chou HC et al. | Multiple hydrogen bonds tuning guest/host excited-state proton transfer reaction: its application in molecular recognition. | 2004 | J. Am. Chem. Soc. | pmid:14871093 |
| LINDSAY JG et al. | C13 isotope effect in the decarboxylation of normal malonic acid. | 1951 | Can J Chem | pmid:14821851 |
| POTTER VR and SIMONSON H | Sequential blocking of metabolic pathways in vivo. | 1951 | Proc. Soc. Exp. Biol. Med. | pmid:14816386 |
| RULON O | The modification of developmental pattern in the sand dollar by malonic acid. | 1951 | Physiol. Zool. | pmid:14807725 |
| pmid:14767925 | ||||
| Le Visage C et al. | Efficacy of paclitaxel released from bio-adhesive polymer microspheres on model superficial bladder cancer. | 2004 | J. Urol. | pmid:14767342 |
| Ohtsuki S et al. | Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14762099 |
| Chovancek M et al. | Development of a fully buffered molybdate electrolyte for capillary electrophoresis with indirect detection and its use for analysis of anions in Bayer liquor. | 2004 | Electrophoresis | pmid:14760635 |
| Nam NH et al. | Design of tetrapeptide ligands as inhibitors of the Src SH2 domain. | 2004 | Bioorg. Med. Chem. | pmid:14759738 |
| Scholte AA et al. | Synthesis and biological activity of isopentenyl diphosphate analogues. | 2004 | Bioorg. Med. Chem. | pmid:14759736 |
| Toulmond S et al. | Neuroprotective effects of M826, a reversible caspase-3 inhibitor, in the rat malonate model of Huntington's disease. | 2004 | Br. J. Pharmacol. | pmid:14744804 |
| Huber R et al. | Graded reoxygenation with chemical inhibition of oxidative phosphorylation improves posthypoxic recovery in murine hippocampal slices. | 2004 | J. Neurosci. Res. | pmid:14743458 |
| pmid:14737650 | ||||
| Paucard A et al. | Biphasic modulation by nitric oxide of caspase activation due to malonate injection in rat striatum. | 2004 | Eur. J. Pharmacol. | pmid:14729115 |
| Shiva S et al. | Mechanisms of the interaction of nitroxyl with mitochondria. | 2004 | Biochem. J. | pmid:14723605 |
| Kato F and Hiroi K | Stereochemistry of the asymmetric carbopalladation of allenes followed by nucleophilic substitution reactions with carbo- and aminonucleophiles. | 2004 | Chem. Pharm. Bull. | pmid:14709874 |
| Maklashina E et al. | Effect of oxygen on activation state of complex I and lack of oxaloacetate inhibition of complex II in Langendorff perfused rat heart. | 2004 | FEBS Lett. | pmid:14706827 |
| pmid:14706641 | ||||
| pmid:14704058 | ||||
| Besson VC et al. | Deleterious activation of poly(ADP-ribose)polymerase-1 in brain after in vivo oxidative stress. | 2003 | Free Radic. Res. | pmid:14703732 |
| Demianová Z et al. | Nonaqueous capillary electrophoretic separation of polyphenolic compounds in wine using coated capillaries at high pH in methanol. | 2003 | Electrophoresis | pmid:14679573 |
| pmid:14677975 | ||||
| Holyoak T et al. | Malonate: a versatile cryoprotectant and stabilizing solution for salt-grown macromolecular crystals. | 2003 | Acta Crystallogr. D Biol. Crystallogr. | pmid:14646118 |
| Alfinito PD et al. | Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively. | 2003 | J. Neurosci. | pmid:14645494 |
| Blank M and Soo L | Electromagnetic acceleration of the Belousov-Zhabotinski reaction. | 2003 | Bioelectrochemistry | pmid:14642914 |
| pmid:14640665 | ||||
| pmid:14630063 | ||||
| Lange G et al. | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. | 2003 | J. Med. Chem. | pmid:14613321 |
| pmid:14606847 | ||||
| pmid:14606824 | ||||
| Pan D et al. | PathMAPA: a tool for displaying gene expression and performing statistical tests on metabolic pathways at multiple levels for Arabidopsis. | 2003 | BMC Bioinformatics | pmid:14604444 |
| Fancellu R et al. | Neuroprotective effects mediated by dopamine receptor agonists against malonate-induced lesion in the rat striatum. | 2003 | Neurol. Sci. | pmid:14598076 |
| Dorovskikh VA et al. | [The antioxidizing activity of malonic acid derivatives]. | 1992 May-Jun | Eksp Klin Farmakol | pmid:1458159 |
| Sinha AK et al. | Microwave-assisted rapid synthesis of methyl 2,4,5-trimethoxyphenylpropionate, a metabolite of Cordia alliodora. | 2003 | Nat. Prod. Res. | pmid:14577691 |
| Kang J et al. | Electronic g-factor measurement from ENDOR-induced EPR patterns: malonic acid and guanine hydrochloride dihydrate. | 2003 | J. Magn. Reson. | pmid:14568523 |
| Haas R et al. | Conversion of adamsite (phenarsarzin chloride) by fungal manganese peroxidase. | 2004 | Appl. Microbiol. Biotechnol. | pmid:14564485 |
| pmid:14558847 | ||||
| pmid:14552617 | ||||
| Sun F and Darbre T | The Co(I) induced methylmalonyl-succinyl rearrangement in a model for the coenzyme B12 dependent methylmalonyl-CoA mutase. | 2003 | Org. Biomol. Chem. | pmid:14527146 |
| Brinkmann T et al. | Photoformation of low-molecular-weight organic acids from brown water dissolved organic matter. | 2003 | Environ. Sci. Technol. | pmid:14524452 |
| pmid:14510532 | ||||
| pmid:14501124 | ||||
| pmid:14453317 | ||||
| HAYAISHI O | Enzymatic decarboxylation of malonic acid. | 1955 | J. Biol. Chem. | pmid:14392148 |
| Neguţ M et al. | [Value of some enzyme tests used in practice for identification of enterobacteria]. | 1977 Apr-Jun | Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol | pmid:143713 |
| WOLFE JB et al. | Malonate oxidation by dry cells and cell-free extracts of Pseudomonas fluorescens. | 1955 | J. Bacteriol. | pmid:14367265 |
| GATENBECK S and BENTLEY R | NAPHTHAQUINONE BIOSYNTHESIS IN MOULDS: THE MECHANISM FOR FORMATION OF JAVANICIN. | 1965 | Biochem. J. | pmid:14348208 |
| QUAGLIARIELLO E et al. | THE OXIDATION OF GLUTAMATE BY RAT-LIVER MITOCHONDRIA. | 1965 | Biochem. J. | pmid:14342510 |
| BALAZS R and HASLAM J | EXCHANGE TRANSAMINATION AND THE METABOLISM OF GLUTAMATE IN BRAIN. | 1965 | Biochem. J. | pmid:14342220 |
| BALAZS R | CONTROL OF GLUTAMATE OXIDATION IN BRAIN AND LIVER MITOCHONDRIAL SYSTEMS. | 1965 | Biochem. J. | pmid:14340100 |
| SMITH RM and OSBORNE-WHITE WS | METABOLISM OF PROPIONATE BY SHEEP LIVER. OXIDATION OF PROPIONATE BY HOMOGENATES. | 1965 | Biochem. J. | pmid:14340092 |
| FRIEDMAN SM et al. | ANTIBIOTIC GLYCOSIDES. V. A COMPARISON OF 2-METHYLMALONATE AND PROPIONATE AS PERCURSORS OF THE C21 BRANCHED CHAIN LACTONE IN ERYTHROMYCIN. | 1964 | J. Biol. Chem. | pmid:14209973 |
| KOMINEK LA and HALVORSON HO | MODE OF INHIBITION OF SPORULATION OF BACILLUS CEREUS BY ETHYL MALONATE AND ETHYL SUCCINATE. | 1964 | J. Bacteriol. | pmid:14197898 |
| ROBBINS E et al. | DYNAMICS OF ACRIDINE ORANGE-CELL INTERACTION. II. DYE-INDUCED ULTRASTRUCTURAL CHANGES IN MULTIVESICULAR BODIES (ACRIDINE ORANGE PARTICLES). | 1964 | J. Cell Biol. | pmid:14154495 |
| SMITH JA and DELUCA HF | STRUCTURAL CHANGES IN ISOLATED LIVER MITOCHONDRIA OF RATS DURING ESSENTIAL FATTY ACID DEFICIENCY. | 1964 | J. Cell Biol. | pmid:14154491 |
| GOLLAKOTA KG and HALVORSON HO | BIOCHEMICAL CHANGES OCCURRING DURING SPORULATION OF BACILLUS CEREUS T. II. EFFECT OF ESTERS OF ORGANIC ACIDS ON SPORULATION. | 1963 | J. Bacteriol. | pmid:14047234 |
| CRAWFORD MA | The effects of fluoroacetate, malonate and acid-base balance on the renal disposal of citrate. | 1963 | Biochem. J. | pmid:14023730 |
| pmid:14016247 | ||||
| pmid:13999968 | ||||
| pmid:13980177 | ||||
| pmid:13969382 | ||||
| pmid:13969381 | ||||
| pmid:13952695 |