Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Nerve Degeneration D009410 53 associated lipids
Fever D005334 35 associated lipids
Catalepsy D002375 30 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Parkinson Disease D010300 53 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Insulin Resistance D007333 99 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Prorok M and Castellino FJ Thermodynamics of binding of calcium, magnesium, and zinc to the N-methyl-D-aspartate receptor ion channel peptidic inhibitors, conantokin-G and conantokin-T. 1998 J. Biol. Chem. pmid:9677382
Gregg AR et al. Combined malonic and methylmalonic aciduria with normal malonyl-coenzyme A decarboxylase activity: a case supporting multiple aetiologies. 1998 J. Inherit. Metab. Dis. pmid:9700595
Hariharan M and Allewell NM Effects of the T-->R transition on the electrostatic properties of E. coli aspartate transcarbamylase. 1998 Proteins pmid:9714159
Hofrichter M et al. Oxidative decomposition of malonic acid as basis for the action of manganese peroxidase in the absence of hydrogen peroxide. 1998 FEBS Lett. pmid:9742955
Bonkowsky HL and Pomeroy JS Assay of delta-aminolevulinic acid synthetase in homogenates of mouse, rat, and human liver: species differences in requirement for an exogenous succinyl-CoA-generating system. 1978 Anal. Biochem. pmid:9762086
Rutkoski A and Jaworski JG An improved synthesis of malonyl-coenzyme A. 1978 Anal. Biochem. pmid:9762122
Simonyan RA and Skulachev VP Thermoregulatory uncoupling in heart muscle mitochondria: involvement of the ATP/ADP antiporter and uncoupling protein. 1998 FEBS Lett. pmid:9771898
Zeevalk GD et al. Excitotoxicity and oxidative stress during inhibition of energy metabolism. 1998 Dev. Neurosci. pmid:9778583
An JH and Kim YS A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli. 1998 Eur. J. Biochem. pmid:9826185
Kolb S et al. The fermenting bacterium Malonomonas rubra is phylogenetically related to sulfur-reducing bacteria and contains a c-type cytochrome similar to those of sulfur and sulfate reducers. 1998 Syst. Appl. Microbiol. pmid:9841124