| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Neurofibromatosis 1 | D009456 | 4 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schlüter A et al. | Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy. | 2012 | Hum. Mol. Genet. | pmid:22095690 |
| Amaral AU et al. | Ethylmalonic acid impairs brain mitochondrial succinate and malate transport. | 2012 | Mol. Genet. Metab. | pmid:22133302 |
| Liu Q et al. | Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells. | 2012 | Small | pmid:22508680 |
| Mitra T et al. | Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions. | 2012 | J Mater Sci Mater Med | pmid:22367159 |
| Du X et al. | [Design, synthesis and evaluation of malonic acid-based PTP1B inhibitors]. | 2012 | Yao Xue Xue Bao | pmid:22645761 |
| Park SY et al. | An analysis of the concentration change of intermediate metabolites by gene manipulation in fatty acid biosynthesis. | 2012 | Enzyme Microb. Technol. | pmid:22664193 |
| Liu Z et al. | The effects of dynamic changes of malonyl ginsenosides on evaluation and quality control of Panax ginseng C.A. Meyer. | 2012 | J Pharm Biomed Anal | pmid:22387101 |
| Martin FP et al. | Metabolomic applications to decipher gut microbial metabolic influence in health and disease. | 2012 | Front Physiol | pmid:22557976 |
| Xue J et al. | Novel compound heterozygous mutation of MLYCD in a Chinese patient with malonic aciduria. | 2012 | Mol. Genet. Metab. | pmid:22104738 |
| Maune MW and Tanner RS | Description of Anaerobaculum hydrogeniformans sp. nov., an anaerobe that produces hydrogen from glucose, and emended description of the genus Anaerobaculum. | 2012 | Int. J. Syst. Evol. Microbiol. | pmid:21602364 |
| Liew CW et al. | Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis. | 2012 | J. Biol. Chem. | pmid:22589546 |
| Anand K et al. | Structural analyses of the Slm1-PH domain demonstrate ligand binding in the non-canonical site. | 2012 | PLoS ONE | pmid:22574179 |
| Moldes D et al. | Role of laccase and low molecular weight metabolites from Trametes versicolor in dye decolorization. | 2012 | ScientificWorldJournal | pmid:22566767 |
| Tao X et al. | Digital gene expression analysis based on integrated de novo transcriptome assembly of sweet potato [Ipomoea batatas (L.) Lam]. | 2012 | PLoS ONE | pmid:22558397 |
| Ashrafian H et al. | Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. | 2012 | Cell Metab. | pmid:22405071 |
| Trushina E et al. | Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. | 2012 | PLoS ONE | pmid:22393443 |
| Tran QM et al. | Out of plane distortions of the heme b of Escherichia coli succinate dehydrogenase. | 2012 | PLoS ONE | pmid:22393428 |
| Totir M et al. | Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization. | 2012 | PLoS ONE | pmid:22393408 |
| Hackett NR et al. | RNA-Seq quantification of the human small airway epithelium transcriptome. | 2012 | BMC Genomics | pmid:22375630 |
| Merewitz EB et al. | Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. | 2012 | J. Exp. Bot. | pmid:22131157 |